Cheap bus tickets from Philadelphia to Knoxville
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Bus from Philadelphia to Knoxville: Journey Information
There is one daily bus from Philadelphia to Knoxville. Traveling by bus from Philadelphia to Knoxville usually takes around 19 hours and 56 minutes, but the fastest FlixBus US bus can make the trip in 15 hours and 40 minutes.
- Distance
- 551 mi (886 km)
- Shortest duration
- 15h 40m
- Cheapest price
- RON 395.21
- Trips per day
- 1
- Most frequent service
- FlixBus US
- Bus lines
- 1
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Philadelphia to Knoxville Bus Schedule

There are several bus options that can take you from Philadelphia to Knoxville:
See more detailsHow much is a bus ticket from Philadelphia to Knoxville?
Bus tickets for a trip from Philadelphia to Knoxville cost about RON 422 when you book at the cheapest time, 15 days ahead. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Philadelphia to Knoxville by travel date
If you're planning to travel by bus from Philadelphia to Knoxville in the next month, the average ticket price is expected to range from RON 393 to RON 580. The cheapest bus tickets available in the next few weeks are for trips departing on December 7, 2026. If you’re looking to travel to Knoxville this week, bus tickets are available starting at RON 484.
Average bus ticket prices from Philadelphia to Knoxville by month
Taking the bus from Philadelphia to Knoxville is usually cheapest in September, when the average ticket price is only RON 532. If you're planning to take the bus from Philadelphia to Knoxville during December, keep in mind that bus ticket prices may be higher than usual, with an average price of RON 757. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 15 days in advance. This way, you can save up to RON 306.60 on your bus ticket compared to booking last-minute.
What bus companies travel from Philadelphia to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Philadelphia to Knoxville. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 19h 56m | RON 561.68 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trip per day from Philadelphia to Knoxville, and the average ticket for this route costs only RON 561.68.






Frequently asked questions about traveling by bus from Philadelphia to Knoxville
There is usually only one bus per day from Philadelphia to Knoxville. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.
Trips per day
1
Direct trips
0
The bus takes an average of 19 hours and 56 minutes to cover the 551 miles from Philadelphia to Knoxville. However, the fastest bus only takes 15 hours and 40 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
551
Distance (km)
886
There is usually only one bus per day from Philadelphia to Knoxville. It leaves the station in Philadelphia at 11:55 PM each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
Earliest bus
2:05am
Latest bus
11:55pm
Sunday tends to be the busiest day for buses, as many passengers take the bus to Knoxville at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
Most crowded
Sunday
Least crowded
Thursday
City Information
Philadelphia



We may feel a little bit more than just brotherly love for Philadelphia, a city steeped in history and culture. Where else can you channel your inner Rocky Balboa on his epic run, and later enjoy an authentic Philly cheesesteak as a reward?
Philadelphia’s affordability (especially compared to other East Coast cities) is just one of many reasons it is among Wanderu’s best destinations for college students. Another reason is how much there is to do! Early American history takes precedence at Independence Hall and the Liberty Bell, while museums abound on Benjamin Franklin Parkway, sometimes called the most artistic mile in the city. Head to Reading Terminal Market to fuel up for a night hitting the bars, clubs, and live music joints that line South Street.
Philadelphia is a major hub for both Greyhound and Amtrak, and its 30th Street Station is one of the busiest stations in the country. The plentitude of ground travel and the nearby Philadelphia International Airport make this exciting city very easily accessible, even on a budget.
Station Information
Where does the bus leave from in Philadelphia?
Main departure station: Philadelphia (Bus Terminal)
Philadelphia has two bus stations with service to Knoxville.
All bus stations in Philadelphia:
- Philadelphia (Bus Terminal)
- Park and Ride off Matthews Rd
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Philadelphia arrive at one main station in Knoxville.
All bus stations in Knoxville:
- Knoxville Bus Station
Plan your next adventure
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