Cheap bus tickets from Philadelphia to Knoxville
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Philadelphia to Knoxville Bus Schedule
Bus from Philadelphia to Knoxville: Journey Information
There are 3 intercity buses per day from Philadelphia to Knoxville. Traveling by bus from Philadelphia to Knoxville usually takes around 21 hours and 38 minutes, but the fastest FlixBus US bus can make the trip in 16 hours and 10 minutes.
| Distance | 551 mi (886 km) |
| Shortest duration | 16h 10m |
| Cheapest price | RON 357.88 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

How much is a bus ticket from Philadelphia to Knoxville?
Bus tickets for a trip from Philadelphia to Knoxville cost RON 381.75 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Philadelphia to Knoxville by month
What bus companies travel from Philadelphia to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Philadelphia to Knoxville. FlixBus US connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 3 | 21h 38m | RON 687.72 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from Philadelphia to Knoxville, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Philadelphia to Knoxville
The bus takes an average of 21 hours and 38 minutes to cover the 551 miles from Philadelphia to Knoxville. However, the fastest bus only takes 16 hours and 10 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Because many passengers travel from Philadelphia to Knoxville at the beginning of the work week, Monday is usually the busiest day for buses. If you are planning to travel on a Monday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Friday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Friday ticket is the way to go.
The first bus leaves at 1:00am and the last bus leaves at 10:00pm. To see the times for all buses from Philadelphia to Knoxville, enter your specific travel dates in the search bar.
City Information
Philadelphia



We may feel a little bit more than just brotherly love for Philadelphia, a city steeped in history and culture. Where else can you channel your inner Rocky Balboa on his epic run, and later enjoy an authentic Philly cheesesteak as a reward?
Philadelphia’s affordability (especially compared to other East Coast cities) is just one of many reasons it is among Wanderu’s best destinations for college students. Another reason is how much there is to do! Early American history takes precedence at Independence Hall and the Liberty Bell, while museums abound on Benjamin Franklin Parkway, sometimes called the most artistic mile in the city. Head to Reading Terminal Market to fuel up for a night hitting the bars, clubs, and live music joints that line South Street.
Philadelphia is a major hub for both Greyhound and Amtrak, and its 30th Street Station is one of the busiest stations in the country. The plentitude of ground travel and the nearby Philadelphia International Airport make this exciting city very easily accessible, even on a budget.
Station Information
Where does the bus leave from in Philadelphia?
Main departure station: 199 Spring Garden St
Philadelphia has two bus stations with service to Knoxville.
All bus stations in Philadelphia:
199 Spring Garden St
Logan Square
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Philadelphia arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
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