Cheap bus tickets from Knoxville to Indianapolis
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Knoxville to Indianapolis Bus Schedule
Bus from Knoxville to Indianapolis: Journey Information
There are 3 intercity buses per day from Knoxville to Indianapolis. Traveling by bus from Knoxville to Indianapolis usually takes around 13 hours and 54 minutes, but the fastest Greyhound bus can make the trip in 10 hours and 35 minutes.
| Distance | 290 mi (467 km) |
| Shortest duration | 10h 35m |
| Cheapest price | TRY 1,893.55 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
How much is a bus ticket from Knoxville to Indianapolis?
Bus tickets for a trip from Knoxville to Indianapolis cost TRY 2,654.43 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Knoxville to Indianapolis by travel date
Over the next four weeks, the average price of bus tickets from Knoxville to Indianapolis is expected to be between TRY 2,316 and TRY 4,884. The cheapest day to travel in the next month is November 18, 2025, when tickets are available for November 18, 2025. The cheapest bus tickets available in the next week start at just TRY 2,358.
Monthly avg. prices
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 14 days in advance. This way, you can save up to TRY 3,613.20 on your bus ticket compared to booking last-minute.
What bus companies travel from Knoxville to Indianapolis?
There is one intercity bus company available to search and book on Wanderu that operates from Knoxville to Indianapolis. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 3 | 13h 54m | TRY 3,242.24 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Knoxville to Indianapolis every day, with the average journey taking around 13 hours and 54 minutes to complete. Bus tickets for Greyhound trips to Indianapolis usually start from TRY 1,894.
Frequently asked questions about traveling by bus from Knoxville to Indianapolis
The bus takes an average of 13 hours and 54 minutes to cover the 290 miles from Knoxville to Indianapolis. However, the fastest bus only takes 10 hours and 35 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to Indianapolis, book your ticket for the last day of the week.
The first bus leaves at 6:00pm and the last bus leaves at 7:00pm. To see the times for all buses from Knoxville to Indianapolis, enter your specific travel dates in the search bar.
City Information
Indianapolis
Indianapolis, or often referred to as just Indy, is the capital and largest city in the state of Indiana. While the city attracts thousands of visitors from the area every month, it is during Memorial Day weekend that Indianapolis becomes the place to be for over 300,000 race car fans from all over the globe. The reason for that is the Indianapolis 500, an annual automobile race and the world’s largest single day sporting event, taking place at the iconic Indianapolis Motor Speedway.
If you’re not in Indianapolis for Memorial Day weekend, you can learn about the race and see a rare collection of 500 Indy race vehicles and memorabilia at the Indianapolis Motor Speedway Museum. And while you’re on a history streak, stop by at one of the many war memorials found throughout the city, like the Soldiers and Sailors monument, the World War II memorial, and the Indiana War Memorial where you must check out the Shrine Room for a stunning one-of-a-kind experience.
Over the past few years, Indianapolis has also been cultivating a vibrant restaurant scene, offering classic American dishes made with ingredients from local farmers, and a growing selection of international cuisine. If you’re a beer fan, you will be happy to know that Indianapolis has some of the highest quality breweries in the U.S.
Located in the heart of America’s Midwest, Indianapolis offers easy connections by bus and train to other Midwestern hubs like Chicago, Louisville, and Cincinnati, while the conveniently located airport connects Indy with the rest of the world.
Station Information
Where does the bus leave from in Knoxville?
Main departure station: Knoxville Bus Station
Most buses depart from the main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
Where does the bus arrive in Indianapolis?
Image credit: Panoramio upload bot
Link to image attributionMain arrival station: 350 S Illinois St
Union Station at 350 S Illinois St in Indianapolis is a major train and bus station which serves the Amtrak Cardinal, and bus carriers including Greyhound, Jefferson Lines, Miller Transportation, and Burlington Trailways. The modern station is located directly south of the historic 1888 Union Station, which now houses a hotel, several restaurants, and a wedding venue. Union Station is in the Wholesale District of downtown Indianapolis, within walking distance to eateries and hotels. There is even an underground, climate-controlled walkway from the station to the nearby Indiana Convention Center and Lucas Oil Stadium, home to the Indianapolis Colts.
All bus stations in Indianapolis:
350 S Illinois St
E Washington St
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