Cheap bus tickets from La Crosse to Minneapolis
Find and compare the best ground travel options in one place.
Bus from La Crosse to Minneapolis: Journey Information
There are 7 intercity buses per day from La Crosse to Minneapolis. Traveling by bus from La Crosse to Minneapolis usually takes around 4 hours and 25 minutes, but the fastest Jefferson Lines bus can make the trip in 3 hours and 45 minutes.
- Distance
- 129 mi (207 km)
- Shortest duration
- 3h 45m
- Cheapest price
- NOK 275.50
- Trips per day
- 6
- Most frequent service
- Jefferson Lines
- Bus lines
- 1
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
La Crosse to Minneapolis Bus Schedule

Bus Trip Reviews from Wanderu Customers
Average score for buses from La Crosse to Minneapolis (Based on 4 ratings and reviews)
5.0
5.0
5.0
There are several bus options that can take you from La Crosse to Minneapolis:
See more detailsPrice trends for buses from La Crosse to Minneapolis
Average bus ticket prices from La Crosse to Minneapolis by travel date
Average bus ticket prices from La Crosse to Minneapolis by month
Prices as travel date approaches
What bus companies travel from La Crosse to Minneapolis?
There is one intercity bus company available to search and book on Wanderu that operates from La Crosse to Minneapolis. Jefferson Lines connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Jefferson Lines | 7 | 4h 25m | NOK 275.50 |
Book Jefferson Lines from La Crosse to Minneapolis from NOK 275.50. There are 7 trips per day offered by Jefferson Lines from La Crosse to Minneapolis and you can expect on average to pay NOK 275.50 for a Jefferson Lines ticket to Minneapolis. In La Crosse, Jefferson Lines departs to Minneapolis from 314 Jay St and one other station. In Minneapolis, Jefferson Lines arrives at 516 2nd Ave North and 2 other stations.
An average trip on Jefferson Lines from La Crosse to Minneapolis takes 4 hours and 25 minutes, while the fastest available Jefferson Lines trip will get you to Minneapolis in 3 hours and 45 minutes.
On weekends, Jefferson Lines offers 5 trips per day. A one way ticket costs NOK 275.50 for a weekend trip to Minneapolis.
Frequently asked questions about traveling by bus from La Crosse to Minneapolis
There are 7 scheduled buses that travel from La Crosse to Minneapolis every day, so you have a decent number of options to choose from. This includes 6 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.
Trips per day
7
Direct trips
6
The bus takes an average of 4 hours and 25 minutes to cover the 129 miles from La Crosse to Minneapolis. However, the fastest bus only takes 3 hours and 45 minutes. In other words, you'll have plenty of time to rest and relax on the road. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
129
Distance (km)
207
The first bus leaves at 1:10pm and the last bus leaves at 4:30pm. To see the times for all buses from La Crosse to Minneapolis, enter your specific travel dates in the search bar.
Earliest bus
1:10pm
Latest bus
4:30pm
Friday is the busiest travel day for buses as people head from La Crosse to Minneapolis for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
Most crowded
Friday
Least crowded
Wednesday
City Information
La Crosse



A busy college town blessed with lush and beautiful green zones, La Crosse is one of the best places to just chill out and unwind. The city's star attraction is the Grandad Bluff, which offers a panoramic view of the entire city and the Mississippi River. Hiking up the hill will certainly be a challenge, but the view from the top makes it all worthwhile. While staying in the city, don't miss out on the chance to go on a cruise aboard the La Crosse Queen, a replica paddle steamer, and unwind while enjoying the sunset. For some family fun, head over to the Children's Museum of La Crosse.
La Crosse does have a pretty reputable food scene, with a strong focus on beers and cheese curds. For an upscale dining experience with the best local dishes, The Waterfront Restaurant & Tavern is a local favorite that has a stellar reputation. Or head to the Dublin Square Irish Pub & Eatery for a combination of good foods and drinks.
La Crosse is easily accessible by bus or train, and regional flights operate out of the La Crosse Municipal Airport.
Minneapolis



Situated along the bank of the Mississippi River in Minnesota, Minneapolis is one of the biggest and most exciting cities to visit in the Midwest. It is home to the Chain of Lakes, where you can swim, fish, boat and even bike or walk along the lakeside trails. It’s no wonder Minneapolis is among the top 10 cities in the U.S. for outdoor activities!
Although it's known as the City of Lakes, Minneapolis has a lot more to offer than gorgeous lakes, wetlands, and waterfalls. Shopaholics can spend days getting lost in the Mall of America, which boasts over 500 stores and an indoor theme park. If you're visiting Minneapolis on a romantic vacation, Minneapolis' bustling theater district offers excellent date nights from dozens of theater companies. Or, for a less musical and more brews-ical date option, head to one of 62 top-rated breweries in the #2 best city in America for craft beer.
Minneapolis can be visited in any season, but keep in mind that it becomes a frigid, snowy destination in the winter. January hovers around 0° Fahrenheit, but it's worth bundling up to enjoy the St. Paul Winter Carnival, or hockey and ice skating on any of the 13 lakes in the city. Have we mentioned how great the lakes are?
If you're visiting both of the Twin Cities, you can take public transport from downtown Minneapolis to Saint Paul in about 30 minutes. Public transit also connects downtown to the Minneapolis–Saint Paul International Airport. Thanks to bus stations throughout Minneapolis, traveling by bus is the easiest way to arrive directly in the middle of the action and begin your adventure.
Station Information
Where does the bus leave from in La Crosse?
Main departure station: 314 Jay St
Buses to La Crosse stop at Jay Street in front of the Grand River Station. The aptly-named grand building features arching ceilings, marble decoration, and amenities like seating and vending machines inside. The station is conveniently located in downtown La Crosse with easy access to surrounding hotels, restaurants, and a rental car agency across the street. Bus lines, including Greyhound and Jefferson Lines, connect La Crosse to Minneapolis, Milwaukee, Chicago, and beyond.
All bus stations in La Crosse:
- 314 Jay St
- University of WI
Where does the bus arrive in Minneapolis?
Main arrival station: 516 2nd Ave North

Located in Central Minneapolis at 950 Hawthorne Ave, the Minneapolis Bus Station is a gateway to nearby cities throughout Minnesota and the Midwest. Greyhound and Jefferson Lines buses operate routes from this station to major cities such as Milwaukee or Chicago and beyond. From the Minneapolis Bus Station, it is a short 12-minute walk to Target Field Station where you can connect to light rail service throughout the city. Vending machines offer snacks or drinks within the station, or head one block south to Hennepin Ave for a variety of restaurant options for hungry travelers.
All bus stations in Minneapolis:
- 516 2nd Ave North
- U of MN - Huron Blvd
- University of Minnesota (Huron Blvd at 2428 Delaware St SE)
Need a return trip from Minneapolis to La Crosse?
Search Bus TicketsPlan your next adventure
More buses from La Crosse
- Green Bay to Chicago BusNOK 323+
- Oshkosh to Milwaukee BusNOK 162+
- Appleton to Milwaukee BusNOK 219+
- La Crosse to Madison BusNOK 238+
- Green Bay to Madison BusNOK 333+
- Green Bay to Minneapolis Bus
- Hudson to Madison BusNOK 380+
- Green Bay to Milwaukee BusNOK 247+
- Milwaukee to Green Bay BusNOK 209+
- Janesville to Milwaukee BusNOK 219+
- Green Bay to Sheboygan BusNOK 152+
- Madison to Milwaukee BusNOK 209+
- Kenosha to Chicago BusNOK 998+
- Fond du Lac to Milwaukee Bus
- Milwaukee to Madison BusNOK 209+
- Sheboygan to Milwaukee BusNOK 133+
- Milwaukee to Chicago BusNOK 314+
Continue by bus from Minneapolis
- Minneapolis to Milwaukee BusNOK 466+
- Minneapolis to Sioux Falls BusNOK 646+
- Minneapolis to Fargo BusNOK 399+
- Minneapolis to Fergus Falls BusNOK 789+
- Minneapolis to Rochester BusNOK 276+
- Minneapolis to Eau Claire BusNOK 190+
- Minneapolis to Indianapolis BusNOK 779+
- Minneapolis to Madison BusNOK 352+
- Minneapolis to Dallas BusNOK 1,216+
- Minneapolis to Bismarck BusNOK 1,017+
- Minneapolis to Des Moines BusNOK 466+
- Minneapolis to Grand Forks BusNOK 618+
- Minneapolis to Duluth BusNOK 380+
- Minneapolis to Kansas City BusNOK 523+
- Minneapolis to Chicago BusNOK 884+
- Minneapolis to Columbus BusNOK 941+
- Minneapolis to La Crosse BusNOK 276+
- Minneapolis to St Paul BusNOK 76+
Check out these popular routes
- New York to Philadelphia BusNOK 276+
- New York to Providence BusNOK 304+
- New York to Ithaca BusNOK 447+
- Toronto to Ottawa BusNOK 323+
- Portland, ME to Boston, MA BusNOK 276+
- Ithaca to New York BusNOK 513+
- Philadelphia to Brooklyn Bus
- Providence to New York BusNOK 323+
- New York to Atlanta BusNOK 931+
- New York, NY to Washington DC BusNOK 333+
- Boston to Portland BusNOK 285+
- Boston to New York BusNOK 352+
- New York to Boston BusNOK 380+
- Edmonton to Calgary BusNOK 257+
- Washington DC to New York, NY BusNOK 314+
- Philadelphia to New York BusNOK 266+
- New York to Montreal BusNOK 798+
- Montreal to New York BusNOK 836+

Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.




