Cheap train tickets from San Diego to St Louis
Find and compare the best ground travel options in one place.
Trip Summary
There are usually 3 daily train trips available from San Diego to St Louis. Traveling by train from San Diego to St Louis usually takes 52 hours and 50 minutes, but the fastest Amtrak train can make the trip in 46 hours and 10 minutes.
- Distance
- 1561 mi (2512 km)
- Fastest train
- 46h 10m
- Lowest price
- RON 1,103.49
- Trains per day
- 0
- Most frequent service
- Amtrak
- Train lines
- 1
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San Diego to St Louis Train Schedule
Is it better to travel by bus or train from San Diego to St Louis?
There are usually 12 daily bus trips available from San Diego to St Louis.
Train | Bus | |
|---|---|---|
Avg. Price | Avg. PriceRON 1,337.25 | Avg. PriceRON 1,100.25Cheaper |
Daily Trips | Daily Trips3 | Daily Trips12 |
Duration | Duration52h 50mFaster | Duration57h 6m |

There are several train options that can take you from San Diego to St Louis:
See more detailsWhat is the price of a train ticket from San Diego to St Louis?
In the last month, the average price of a train ticket from San Diego to St Louis was RON 1,118.12. Considering the distance between San Diego and St Louis, tickets on this route are relatively expensive. Good news! You can find the cheapest tickets if you book your trip at least 26 days prior to the travel date. You’ll likely pay around RON 672.57 more if you wait to book until the last minute.
Average train ticket prices from San Diego to St Louis by travel date
Over the next 30 days, a one-way train trip from San Diego to St Louis will cost between RON 965 and RON 1,856. Book in advance to secure the best price in the next few weeks.
Average train ticket prices from San Diego to St Louis by month
Ticket prices for the train from San Diego to St Louis often fluctuate based on the time of year. For the best prices on this route, book in September when the average ticket price is only RON 1,173. If you're thinking of traveling from San Diego to St Louis during March, keep in mind that train ticket prices may be higher than usual, with an average price of RON 1,501 during this time of year. The best way to score a cheap deal, even in March, is to book your trip well in advance.
Prices as travel date approaches
By booking your train trip from San Diego to St Louis on Wanderu at least 26 days ahead of time, you can save about RON 672.57 on your ticket. Waiting until the last minute means missing out on these savings!
Which train should you take from San Diego to St Louis?
Amtrak is the one and only train line which connects San Diego to St Louis. However, there are 3 trains per day to choose from.
| Train | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Amtrak | 3 | 52h 50m | RON 1,337.24 |
Amtrak is the largest passenger railroad service in America, offering daily intercity trains to hundreds of destinations across the contiguous United States, as well as several cities in Canada. Every Amtrak train comes equipped with comfortable seats with extra legroom, as well as several four-seat areas with tables in the middle. In addition, each car has a freshly cleaned restroom, free WiFi and power outlets at every seat. There are also snack bars where you can purchase drinks or food during your journey. On average, there are 3 Amtrak trains from San Diego to St Louis every day, as well as 5 trips on the weekends, with prices starting from RON 1,103.49.










Frequently asked questions about traveling by train from San Diego to St Louis
There are 3 scheduled trains on most days. Unfortunately, none of them are direct connections, so you will need to disembark from your original train and board a connecting train during your journey. Don't forget to bring your carry-on luggage when you switch trains. In some instances, you may also be responsible for transferring your own checked baggage. You can also take a train for your return trip from St Louis to San Diego. If you're not set on traveling by train, you could always take the bus from San Diego to St Louis for RON 584.
Trains per day
3
Direct trains
0
The distance between San Diego and St Louis is approximately 1561 miles, or 2512 kilometers. The average train journey between these two cities takes 52 hours and 50 minutes, although the absolute fastest you could get there is 46 hours and 10 minutes. Looking for ways to pass the time? Most trains are equipped with Wi-Fi, which means you can stream music, browse social media or get some work done during your ride. That said, in case your train has a spotty signal, or is among the few without Wi-Fi, we also recommend downloading TV shows and movies to your mobile device in advance of your trip. That way the ride will fly by whatever the Wi-Fi situation.
Distance (mi)
1561
Distance (km)
2512
The earliest train departs San Diego at 2:01pm while the last train of the day leaves at 4:10pm. To see all scheduled departure times, use the search function on this page to get the full schedule for your specific travel dates.
First train
2:01pm
Last train
4:10pm
Trains from San Diego to St Louis are the most crowded on Sunday. Tickets also tend to be more expensive then. If you are looking for a great deal on your train tickets or just want extra room to stretch out, consider traveling on Wednesday instead, as it tends to be the least crowded day of the week.
Busiest
Sunday
Least crowded
Wednesday
City Information
San Diego



San Diego is known as "America's Finest City" for its sunny weather, white-sand beaches, and dazzling attractions from Belmont Park to SeaWorld. San Diego's 70 miles of pristine beaches include such gems as Mission Beach, Pacific Beach, La Jolla Cove, and Coronado Beach. The city's strong surfing culture may even inspire you to rent a surfboard and catch the epic waves, bro.
Visitors can spend days getting lost in Balboa Park, a 1,200-acre cultural hub which features 16 museums, immaculate gardens, and the world-famous San Diego Zoo. The historic heart of the city, Old Town, showcases San Diego's heritage and ties to Mexican culture, while other sights like the USS Midway pay tribute to the city's military and maritime history. Leave time for some evening exploring, too! San Diego is rated the #1 best city for craft beer in America, so don't miss out on the bars in the Gaslamp Quarter: 16 walkable blocks packed with nightlife and young crowds.
Two airports, as well as many bus and train options, mean it is easy to get to San Diego from afar or from nearby cities like Tijuana, Los Angeles, Phoenix, and Las Vegas.
St Louis



St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.
Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.
Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.
The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.
Station Information
Where is the train station in San Diego?
Main departure station: Santa Fe Depot

The Santa Fe Depot is the main train station in San Diego and one of the end points of the Pacific Surfliner, the only Amtrak train line that serves the city. The station is also used by the Green Line of the San Diego Trolley light rail transit service and the COASTER commuter rail service that connects the city with the central and northern coastal regions of San Diego County. Opened in 1915, the Santa Fe Depot is famous for its Spanish Colonial Revival Style architecture and grand interior space that features natural redwood beam ceilings and ceramic details. The train station is located in the heart of Downtown San Diego, making it easy to reach from all parts of the city.
All train stations in San Diego:
- Santa Fe Depot - 1050 Kettner Blvd
- 4005 Taylor St
Where is the train station in St Louis?
Main arrival station: Gateway Station - 430 S 15th St

Gateway Station opened in 2008 to consolidate St Louis’ transportation services into one central hub. The station’s award-winning design includes a pedestrian walkway with expansive colored glass windows overlooking the train tracks. Perfectly located in the heart of downtown St Louis, the station is surrounded by bars, restaurants, and hotels and is just a few blocks from Busch Stadium and the iconic Gateway Arch. Amenities inside the station include free Wifi, a food court, and a lounge for Amtrak’s First Class passengers. Gateway Station is a major stop for intercity bus service, several Amtrak train lines, and the city’s MetroLink which can connect you with the St Louis Lambert International Airport in just 30 minutes.
All train stations in St Louis:
- Gateway Station - 430 S 15th St
Need a return trip from St Louis to San Diego?
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