Cheap bus tickets from Mainz to Florence
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Mainz to Florence Bus Schedule
Bus from Mainz to Florence: Journey Information
There are 2 intercity buses per day from Mainz to Florence. Traveling by bus from Mainz to Florence usually takes around 18 hours and 13 minutes, but the fastest FlixBus bus can make the trip in 17 hours and 5 minutes.
| Distance | 453 mi (729 km) |
| Shortest duration | 17h 5m |
| Cheapest price | €87.13 |
| Most frequent service | FlixBus |
| Bus lines | 1 |

What bus companies travel from Mainz to Florence?
There is one intercity bus company available to search and book on Wanderu that operates from Mainz to Florence. FlixBus is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus | 2 | 18h 13m | €93.93 |
First launched in Germany in 2013, FlixBus has become one of the largest intercity bus companies in Europe. Its fleet travels through nearly every country in Europe, including the U.K. FlixBus operates an average of 2 trips from Mainz to Florence, and usually makes the trip in about 18 hours and 13 minutes. On your trip, you'll enjoy Wi-Fi and live GPS, as well as restrooms, air conditioning, and power outlets.
Frequently asked questions about traveling by bus from Mainz to Florence
The bus takes an average of 18 hours and 13 minutes to cover the 453 miles from Mainz to Florence. However, the fastest bus only takes 17 hours and 5 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 4:00pm and the last bus leaves at 10:00pm. To see the times for all buses from Mainz to Florence, enter your specific travel dates in the search bar.
There are usually only 2 buses per day from Mainz to Florence. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.
Need more travel options? Consider taking the train from Mainz to Florence; ticket prices start at €51.23.
City Information
Mainz

Image credit: Pixabay

Image credit: Pixabay

Image credit: Unsplash
Mainz is the state of Rhineland-Palatinate’s capital city and is located along the Rhine River, close to Frankfurt. The city is a cultural center and a transportation hub in the region, known for its delightful wine and historic buildings. The most iconic building in the city is the Mainz Cathedral, a grand Romanesque cathedral over 1,000 years old. The cathedral dominates the historic market square, surrounded by other charming buildings like the iconic half-timbered houses of the area.
Also off the historic market square, you'll find the Gutenberg Museum, dedicated to the history of printing and home to two of Johannes Gutenberg's Bibles. Mainz includes several other noteworthy museums to round out your visit: the Museum of Ancient Seafaring with a focus on Roman ships, Kunsthalle de Mayence, a museum of art, and Landesmuseum Mainz, which focuses on local history.
The Frankfurt Airport is the airport closest to Mainz, and it's easy to take a train to Frankfurt before catching a flight. Of course, trains also connect to other German cities like Stuttgart, Munich, and Hamburg. Mainz is also accessible via intercity bus routes that cover most of Europe.
Florence

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Florence is located in Central-Northern Italy, in the lush Tuscany region. Regarded as the birthplace of the Renaissance, this city is an art lover's idea of heaven. The city’s plethora of museums, palaces, churches, and artistic treasures landed Florence the #1 spot in our ranking of the most cultured cities in Europe.
Visit the Uffizi Gallery to see many of the world's greatest Renaissance masterpieces, including work by Raphael, da Vinci, Botticelli, and Michelangelo. Michelangelo's famous sculpture of David in his birthday suit is on view at the Accademia Galleria. The Institute and Museum of the History of Science is another must-see attraction to learn about the scientific instruments vital to some of the 13th century's world-changing discoveries.
After you have finished exploring Florence's many museums and galleries, head outside to enjoy a relaxing stroll through the Boboli Gardens and appreciate this stunning example of "green architecture."
The city is also home to almost every high-end designer label you can bring to mind, as well as museums dedicated to Gucci and Ferragamo. For a less expensive shopping experience, visit one of the many affordable boutiques and local clothing stores for a more authentic taste of the city.
Florence is a top-rated destination, meaning it has well-established international and national travel connections. Florence's Amerigo Vespucci International Airport makes air travel simple. Fast and modern trains also connect the city to numerous European cities, and many bus carriers offer frequent services to Florence.
Station Information
Where does the bus leave from in Mainz?
Main departure station: Mainz Central Train Station - Exit West
Most buses depart from the main station in Mainz.
All bus stations in Mainz:
Mainz Central Train Station - Exit West
Where does the bus arrive in Florence?
Main arrival station: Viale Filippo Strozzi
Florence Piazzale Montelungo is Florence's central bus terminal located directly next to the main railway station, Firenze SMN. FlixBus, MarinoBus, and Itabus buses depart regularly for cities across Italy, including Pisa, Milan, and Rome. The bus terminal area does not have any amenities, as it relies on those in the main railway station for shops, restaurants and cafes, ticket offices, and waiting areas. The bus terminal is located in the city center and is within walking distance from Florence's main attractions.
All bus stations in Florence:
Viale Filippo Strozzi
Get around town with Moovit
Need a return trip from Florence to Mainz?
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