Cheap bus tickets from Louisville to Knoxville
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Louisville to Knoxville Bus Schedule
Bus from Louisville to Knoxville: Journey Information
There are 4 intercity buses per day from Louisville to Knoxville. Traveling by bus from Louisville to Knoxville usually takes around 13 hours and 12 minutes, but the fastest Greyhound bus can make the trip in 8 hours and 45 minutes.
| Distance | 188 mi (302 km) |
| Shortest duration | 8h 45m |
| Cheapest price | RON 285.94 |
| Most frequent service | Greyhound |
| Bus lines | 1 |

How much is a bus ticket from Louisville to Knoxville?
Bus tickets for a trip from Louisville to Knoxville cost RON 377.58 on average. Consider it a bargain when you can snag tickets for less than RON 377.58. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Monthly avg. prices
What bus companies travel from Louisville to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Louisville to Knoxville. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 4 | 13h 12m | RON 461.65 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 4 bus trips from Louisville to Knoxville every day, with the average journey taking around 13 hours and 12 minutes to complete. Bus tickets for Greyhound trips to Knoxville usually start from RON 286.
Frequently asked questions about traveling by bus from Louisville to Knoxville
The bus takes an average of 13 hours and 12 minutes to cover the 188 miles from Louisville to Knoxville. However, the fastest bus only takes 8 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
The first bus leaves at 2:00am and the last bus leaves at 1:00pm. To see the times for all buses from Louisville to Knoxville, enter your specific travel dates in the search bar.
City Information
Louisville



A mecca for fans of sports, Louisville holds the honor of being the birthplace of many sports legends. Even non-sports fans should not miss out on the Muhammad Ali Center, where tourists can learn more about the life and legacy of the legendary boxer. Aside from permanent galleries dedicated to the boxer himself, the museum also features temporary exhibitions on topics such as race and gender equality. Another top highlight from the city is Churchill Downs, where the famous Kentucky Derby is hosted. Contrary to what people might imagine, the racing track is actually quite idyllic, and if there is one place you must visit in Louisville, this is probably the one. If you are looking for a unique experience, head towards the Louisville Mega Cavern. This cavern system was created out of a 19th-century limestone quarry and it features the world’s only underground zip line course.
Three things dominate the food scene in Louisville: barbecue, bourbon, and mint juleps. Some local favorites are Mark’s Feed Store and Feast BBQ. If you are looking for the finest bourbon, the Evan Williams Bourbon Experience is certainly a good call.
The central bus station in Louisville is the Bus Terminal on W Muhammad Ali Blvd, connecting the city with near and far destinations such as Cincinnati, Chicago and Nashville. There are no train tracks that run through the city. However, the city is still a part of Amtrak’s network via the carrier’s Thruway bus line. The Louisville International Airport fulfills air services for the city.
Station Information
Where does the bus leave from in Louisville?
Main departure station: Louisville Bus Station
The Louisville Bus Terminal, located at 720 W Muhammad Ali Blvd, serves interstate Greyhound bus services. The station is equipped with restrooms, vending machines, and indoor seating. The station also has an adjoining cafeteria in case vending machine snacks aren't enough to satisfy your hunger. In addition, there is also a customer service and ticket kiosk where station staff can answer any questions you may have. The station is located in Downtown Louisville, only a short walk from the city's most exciting amenities and several nearby restaurants and convenience stores.
All bus stations in Louisville:
Louisville Bus Station
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Louisville arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
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