|Shortest Duration||6h 45m|
|Trips per day||5|
Book Greyhound from Louisville to Knoxville from $113.00. There are 5 trips per day offered by Greyhound from Louisville to Knoxville and you can expect on average to pay $130.59 for a Greyhound ticket to Knoxville. In Louisville, Greyhound departs to Knoxville from Bus Terminal - 720 W Muhammad Ali Blvd, In Knoxville, Greyhound arrives at Bus Terminal - 100 E Magnolia Ave,
An average trip on Greyhound from Louisville to Knoxville takes 8 hours and 10 minutes, while the fastest available Greyhound trip will get you to Knoxville in 6 hours and 45 minutes,
On weekends, Greyhound offers 5 trips per day. A one way ticket costs $148.59 for a weekend trip to Knoxville.