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Louisville to Knoxville bus - cost & duration

Cheapest price$115.00
Shortest Duration6h 45m
Trips per day5
bus carriers1
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How to book cheap Louisville to Knoxville bus tickets?

The best way to find cheap deals on bus tickets from Louisville to Knoxville is by booking earlier as most bus companies increase the price as the departure date approaches. Based on the last 30 days, the cheapest average bus fares from Louisville to Knoxville were $117.00. By booking 10 days out, tickets are on average $80.00 cheaper than those that are booked last minute.

What is the busiest time to travel by bus from Louisville to Knoxville?

The busiest time of the week for travel from Louisville to Knoxville by bus is usually around 9:00 AM on Friday. When planning to travel around this time, tickets should be booked well in advance as they may sell out and you may find buses more full than usual. Around 4:00 PM on Tuesday tends to be when the fewest number of bus tickets are sold. If you’re looking for a little extra space, buses departing at this time are the least likely to be crowded.

Greyhound from Louisville to Knoxville has the most daily schedules

On average there are 5 scheduled bus trips per day. Greyhound has the most regularly scheduled departures from Louisville to Knoxville, with an average of 5 trips per day and 63 monthly trips. One bus carrier currently travels from Louisville to Knoxville. Of the 5 trips there all of the schedules require a connection as there are no direct trips. A connection will generally require disembarking from the bus and boarding another bus to complete your trip.

1 carriers offer Louisville to Knoxville bus trips


Book Greyhound from Louisville to Knoxville from $113.00. There are 5 trips per day offered by Greyhound from Louisville to Knoxville and you can expect on average to pay $130.59 for a Greyhound ticket to Knoxville. In Louisville, Greyhound departs to Knoxville from Bus Terminal - 720 W Muhammad Ali Blvd, In Knoxville, Greyhound arrives at Bus Terminal - 100 E Magnolia Ave,

An average trip on Greyhound from Louisville to Knoxville takes 8 hours and 10 minutes, while the fastest available Greyhound trip will get you to Knoxville in 6 hours and 45 minutes,

On weekends, Greyhound offers 5 trips per day. A one way ticket costs $148.59 for a weekend trip to Knoxville.

Extra legroom
Power outlet
Air conditioning
Avg. Time
8h 10m
Avg. Price

Plan your next adventure:

Depending on the bus line you travel with, your options include one station that has bus departures from Louisville. Most bus trips to Knoxville will depart from Bus Terminal - 720 W Muhammad Ali Blvd.
  • Bus Terminal - 720 W Muhammad Ali Blvd
Bus trips arrive in Knoxville at 1 stations, depending on which bus line you are traveling with. Bus Terminal - 100 E Magnolia Ave are the main bus stations in Knoxville for trips arriving from Louisville.
  • Bus Terminal - 100 E Magnolia Ave