Cheap bus tickets from Baltimore to Knoxville
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Bus from Baltimore to Knoxville: Journey Information
There are 2 intercity buses per day from Baltimore to Knoxville. Traveling by bus from Baltimore to Knoxville usually takes around 16 hours and 2 minutes, but the fastest Greyhound bus can make the trip in 13 hours and 10 minutes.
- Distance
- 461 mi (742 km)
- Shortest duration
- 13h 10m
- Cheapest price
- RON 292.23
- Trips per day
- 2
- Most frequent service
- Greyhound
- Bus lines
- 2
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There are several bus options that can take you from Baltimore to Knoxville:
See more detailsHow much is a bus ticket from Baltimore to Knoxville?
Bus tickets for a trip from Baltimore to Knoxville cost about RON 292 when you book at the cheapest time, 26 days ahead. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Baltimore to Knoxville by travel date
If you're planning to travel by bus from Baltimore to Knoxville in the next month, the average ticket price is expected to range from RON 398 to RON 647. The cheapest bus tickets available in the next few weeks are for trips departing on November 13, 2026. If you’re looking to travel to Knoxville this week, bus tickets are available starting at RON 398.
Average bus ticket prices from Baltimore to Knoxville by month
Taking the bus from Baltimore to Knoxville is usually cheapest in September, when the average ticket price is only RON 350. If you're planning to take the bus from Baltimore to Knoxville during January, keep in mind that bus ticket prices may be higher than usual, with an average price of RON 446. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 26 days in advance. This way, you can save up to RON 228.64 on your bus ticket compared to booking last-minute.
What bus companies travel from Baltimore to Knoxville?
There are two bus lines that have daily service from Baltimore to Knoxville that you can compare and book on Wanderu. However, each company only runs one bus per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 18h 29m | RON 472.47 |
| Greyhound | 1 | 13h 49m | RON 394.96 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trip per day from Baltimore to Knoxville, and the average ticket for this route costs only RON 472.47.






Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trip from Baltimore to Knoxville every day, with the average journey taking around 13 hours and 49 minutes to complete. Bus tickets for Greyhound trips to Knoxville usually start from RON 292.23.






Frequently asked questions about traveling by bus from Baltimore to Knoxville
There are usually only 2 buses per day from Baltimore to Knoxville. One bus is a direct connection, meaning that you can stay on the same vehicle for the entire trip, without having to transfer onto a connecting bus at any point.
Trips per day
2
Direct trips
1
The bus takes an average of 16 hours and 2 minutes to cover the 461 miles from Baltimore to Knoxville. However, the fastest bus only takes 13 hours and 10 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
461
Distance (km)
742
The first bus leaves at 4:35 AM and the last bus leaves at 11:25 PM. To see the times for all buses from Baltimore to Knoxville, enter your specific travel dates in the search bar.
Earliest bus
4:35am
Latest bus
11:25pm
Saturday is usually the day when buses are busiest, as many travelers take the bus to enjoy the weekend in Knoxville. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
Most crowded
Saturday
Least crowded
Monday
City Information
Baltimore



Baltimore is a seaport in Maryland best known for its crab cakes and baseball legend, Babe Ruth. As there is plenty to see in Charm City, you'll be singing “Good Morning, Baltimore” as soon as you experience all of the sights and activities this quirky town has to offer.
Some of Baltimore's most impressive attractions are centered in and around Inner Harbor. This scenic waterfront is filled with historic ships, dating as far back as the Civil War in the case of the USS Constellation. Alongside shops and restaurants, Inner Harbor also hosts the National Aquarium, the Maryland Science Center, and several entertainment venues where you can catch live music. Enjoy a bird's-eye view of the harbor from atop Federal Hill Park, or if you prefer the view that inspired “The Star Spangled Banner,” head out to Fort McHenry, known for its role in the War of 1812.
Baltimore is one of the stops on Wanderu's recommended East Coast wine tour, but don't worry about racking up a hefty tab; luckily, Baltimore is also one of the cheapest drinking cities in the U.S., with the cheapest bottle of beer going for just $1.42. Enjoy your wine or beer along the Avenue in Hampden, a neighborhood known for its hipster bars, restaurants, and boutiques.
Ready to plan your Baltimore adventure? Numerous bus and train options make Baltimore affordably accessible by ground transportation, and Baltimore-Washington International Airport not only offers hundreds of daily flights, it also is one of the best airports for food in the U.S.
Station Information
Where does the bus leave from in Baltimore?
Main departure station: Baltimore Bus Terminal

The bus terminal located at 2110 Haines St is the main bus station in Baltimore. Opened in 2016, the station serves as the main stop near Downtown Baltimore for the two largest bus carriers that conduct trips in and out of the city – Greyhound and Peter Pan Bus Lines. The station is served by only one line of Baltimore’s transit bus network. However, a connection is also available to the University of Maryland, Baltimore County bus system. As there aren’t many food options near the Baltimore Bus Terminal, we suggest bringing your own sandwich if you think you’ll get hungry during your trip.
All bus stations in Baltimore:
- Bus Terminal - 2110 Haines St
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Baltimore arrive at one main station in Knoxville.
All bus stations in Knoxville:
- Knoxville Bus Station
Need a return trip from Knoxville to Baltimore?
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