Cheap bus tickets from Baltimore to Knoxville
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Bus from Baltimore to Knoxville: Journey Information
There is one daily bus from Baltimore to Knoxville. Traveling by bus from Baltimore to Knoxville usually takes around 16 hours and 38 minutes, but the fastest Greyhound bus can make the trip in 16 hours and 30 minutes.
| Distance | 461 mi (742 km) |
| Shortest duration | 16h 30m |
| Cheapest price | $54.47 |
| Most frequent service | Greyhound |
| Bus lines | 2 |
Bus Trip Reviews from Wanderu Customers
Average score for buses from Baltimore to Knoxville
(Based on 1 ratings and reviews)
5.0
How much is a bus ticket from Baltimore to Knoxville?
Bus tickets for a trip from Baltimore to Knoxville cost $63.75 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Baltimore to Knoxville by travel date
If you're planning to travel by bus from Baltimore to Knoxville in the next month, the average ticket price is expected to range from $58 to $89. The cheapest bus tickets available in the next few weeks are for trips departing on May 13, 2025.
If you’re looking to travel to Knoxville this week, bus tickets are available starting at $67.
Average bus ticket prices from Baltimore to Knoxville by month
Bus tickets from Baltimore to Knoxville are at their cheapest average price in May. This time of year usually offers the best deals on bus tickets for this route, with ticket prices around $52. On the other hand, traveling on this route during November might cost you a bit more than usual. Bus tickets for November trips cost $76, on average. But no need to stress — booking your bus ticket in advance can help you snag cheaper tickets.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 28 days in advance. This way, you can save up to $66.18 on your bus ticket compared to booking last-minute.
What bus companies travel from Baltimore to Knoxville?
There are two bus lines that have daily service from Baltimore to Knoxville that you can compare and book on Wanderu. However, each company only runs one bus per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 19h 20m | $102.31 |
| Greyhound | 1 | 16h 36m | $78.49 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Baltimore to Knoxville, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from Baltimore to Knoxville every day, with the average journey taking around 16 hours and 36 minutes to complete. Bus tickets for Greyhound trips to Knoxville usually start from $54.
Frequently asked questions about traveling by bus from Baltimore to Knoxville
The bus takes an average of 16 hours and 38 minutes to cover the 461 miles from Baltimore to Knoxville. However, the fastest bus only takes 16 hours and 30 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
There is usually only one bus per day from Baltimore to Knoxville. It leaves the station in Baltimore at 11:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
There is usually only one bus per day from Baltimore to Knoxville. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.
City Information
Baltimore
Baltimore is a seaport in Maryland best known for its crab cakes and baseball legend, Babe Ruth. As there is plenty to see in Charm City, you'll be singing "Good Morning, Baltimore'' as soon as you experience all of the sights and activities this quirky town has to offer.
Some of Baltimore's most impressive attractions are centered in and around Inner Harbor. This scenic waterfront is filled with historic ships, dating as far back as the Civil War in the case of the USS Constellation. Alongside shops and restaurants, Inner Harbor also hosts the National Aquarium, the Maryland Science Center, and several entertainment venues where you can catch live music. Enjoy a bird's-eye view of the harbor from atop Federal Hill Park, or if you prefer the view that inspired "The Star Spangled Banner," head out to Fort McHenry, known for its role in the War of 1812.
Baltimore is one of the stops on Wanderu's recommended East Coast wine tour, but don't worry about racking up a hefty tab; luckily, Baltimore is also one of the cheapest drinking cities in the U.S., with the cheapest bottle of beer going for just $1.42. Enjoy your wine or beer along the Avenue in Hampden, a neighborhood known for its hipster bars, restaurants, and boutiques.
Ready to plan your Baltimore adventure? Numerous bus and train options make Baltimore affordably accessible by ground transportation, and Baltimore-Washington International Airport not only offers hundreds of daily flights, it also is one of the best airports for food in the U.S.
Station Information
Where does the bus leave from in Baltimore?
Image credit: STV Incorporated
Main departure station: Bus Terminal - 2110 Haines St
The bus terminal located at 2110 Haines St is the main bus station in Baltimore. Opened in 2016, the station serves as the main stop near Downtown Baltimore for the two largest bus carriers that conduct trips in and out of the city – Greyhound and Peter Pan Bus Lines. The station is served by only one line of Baltimore’s transit bus network. However, a connection is also available to the University of Maryland, Baltimore County bus system. As there aren’t many food options near the Baltimore Bus Terminal, we suggest bringing your own sandwich if you think you’ll get hungry during your trip.
All bus stations in Baltimore:
Bus Terminal - 2110 Haines St
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Baltimore arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
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