Cheap bus tickets from Greenville to Columbus
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Greenville to Columbus Bus Schedule
Bus from Greenville to Columbus: Journey Information
There are 2 intercity buses per day from Greenville to Columbus. Traveling by bus from Greenville to Columbus usually takes around 19 hours and 40 minutes, but the fastest FlixBus US bus can make the trip in 14 hours and 55 minutes.
| Distance | 355 mi (571 km) |
| Shortest duration | 14h 55m |
| Cheapest price | TRY 2,356.31 |
| Most frequent service | Greyhound |
| Bus lines | 2 |

How much is a bus ticket from Greenville to Columbus?
Bus tickets for a trip from Greenville to Columbus cost TRY 3,244.77 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Greenville to Columbus by travel date
Over the next four weeks, the average price of bus tickets from Greenville to Columbus is expected to be between TRY 2,653 and TRY 6,653. The cheapest day to travel in the next month is November 17, 2025, when tickets are available for November 17, 2025. The cheapest bus tickets available in the next week start at just TRY 2,905.
Monthly avg. prices
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 18 days in advance. This way, you can save up to TRY 4,487.35 on your bus ticket compared to booking last-minute.
What bus companies travel from Greenville to Columbus?
There are two bus lines that have daily service from Greenville to Columbus that you can compare and book on Wanderu. However, each company only runs one bus per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 2 | 20h 51m | TRY 6,428.48 |
| Greyhound | 1 | 19h 35m | TRY 3,810.27 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Greenville to Columbus, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from Greenville to Columbus every day, with the average journey taking around 19 hours and 35 minutes to complete. Bus tickets for Greyhound trips to Columbus usually start from TRY 2,356.
Frequently asked questions about traveling by bus from Greenville to Columbus
The bus takes an average of 19 hours and 40 minutes to cover the 355 miles from Greenville to Columbus. However, the fastest bus only takes 14 hours and 55 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Friday is the busiest travel day for buses as people head from Greenville to Columbus for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
The first bus leaves at 11:00am and the last bus leaves at 10:00pm. To see the times for all buses from Greenville to Columbus, enter your specific travel dates in the search bar.
There are usually only 2 buses per day from Greenville to Columbus. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.
Need more travel options? Consider taking the train from Greenville, SC to Columbus, OH; ticket prices start at TRY 9,474.08.
City Information
Greenville

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
Columbus



Brimming with life and cultural events, Columbus is the affordable destination of your dreams! Featuring a budding art scene, Columbus attracts art lovers through the exhibitions at the Columbus Museum of Arts where children and adults alike can indulge in thought-provoking artworks. Fans of sports should not miss out on a baseball game at Huntington Park, which offers reasonably-priced tickets; it is also rarely crowded. For those who simply want to stroll about, the German Village offers a quaint and scenic view rarely seen elsewhere.
As the sun goes down, dig deeper into the German heritage of Columbus by enjoying a traditional schnitzel dish at the Schmidt's Restaurant and Sausage Haus. When you are looking for a quick snack, Bodega serves some of the best sandwiches in town, and there are up to 47 varieties of craft beers for you to choose from.
Columbus’ busiest bus station is located on E Town St., and it offers intercity bus trips to Cleveland, Chicago, New York and many other cities. The Columbus Union Station was the first union station ever built, and it’s served by Amtrak’s Lake Shore Limited and Capitol Limited train lines. The local airport, the John Glenn Columbus International Airport, is located on the east side of the city, 6 miles east of Downtown. It provides access to 31 other airports.
Station Information
Where does the bus leave from in Greenville?
Main departure station: 1116 Woodruff Rd
Most buses depart from the main station in Greenville.
All bus stations in Greenville:
1116 Woodruff Rd
Where does the bus arrive in Columbus?
Main arrival station: Columbus (E Mound St)
These are the two stations where buses may stop when they arrive in Columbus.
All bus stations in Columbus:
Columbus (E Mound St)
100 E Rich St
Get around town with Moovit
Need a return trip from Columbus to Greenville?
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