Typically there are 7 schedules to compare for your trip to Brno. One train carrier operates regular service on the Český Krumlov to Brno route. RegioJet offers the most scheduled departures between Český Krumlov to Brno, usually offering 7 trips per day. On this route there are no direct schedules. This means that along your journey from Český Krumlov to Brno, you will need to disembark from the first train and board a connecting train. Depending on the carrier's policy, you may be responsible for transferring your own checked luggage, but you will definitely need to bring your hand luggage.
Are you not set on traveling by train? Take a look at Bus tickets from Český Krumlov to Brno, which start at $21.75.
RegioJet train tickets from Český Krumlov to Brno start from $19.75, and on average cost $22.23. Daily there are 7 RegioJet schedules to Brno. RegioJet in Český Krumlov leaves from Bus Station and one other station. And in Brno trains arrive at Židenice and 2 other train stations.
From Český Krumlov to Brno train travel on RegioJet takes 10 hours and 59 minutes. If you are looking to get to Brno faster, RegioJet offers more express schedule options with a travel time of 9 hours and 30 minutes.