Cheap bus tickets from Mississauga to Buffalo
Find and compare the best ground travel options in one place.
Bus from Mississauga to Buffalo: Journey Information
There are 6 intercity buses per day from Mississauga to Buffalo. Traveling by bus from Mississauga to Buffalo usually takes around 5 hours and 22 minutes, but the fastest Adirondack Trailways bus can make the trip in 2 hours and 45 minutes.
- Distance
- 62 mi (100 km)
- Shortest duration
- 2h 45m
- Cheapest price
- CZK 433.99
- Trips per day
- 2
- Most frequent service
- FlixBus US
- Bus lines
- 3
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Mississauga to Buffalo Bus Schedule

There are several bus options that can take you from Mississauga to Buffalo:
- Adirondack Trailways: 1 daily buses from CZK 434
- FlixBus US: 6 daily buses from CZK 443
- Greyhound: 2 daily buses from CZK 551
How much is a bus ticket from Mississauga to Buffalo?
Bus tickets for a trip from Mississauga to Buffalo cost CZK 656 on average. Opting to take a bus is a wallet-friendly way to make this trip. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Mississauga to Buffalo by travel date
If you're planning to travel by bus from Mississauga to Buffalo in the next month, the average ticket price is expected to range from CZK 584 to CZK 1,061. The cheapest bus tickets available in the next few weeks are for trips departing on October 20, 2026. If you’re looking to travel to Buffalo this week, bus tickets are available starting at CZK 584.
Average bus ticket prices from Mississauga to Buffalo by month
Taking the bus from Mississauga to Buffalo is usually cheapest in March, when the average ticket price is only CZK 541. If you're planning to take the bus from Mississauga to Buffalo during August, keep in mind that bus ticket prices may be higher than usual, with an average price of CZK 801. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 28 days in advance. This way, you can save up to CZK 193.51 on your bus ticket compared to booking last-minute.
What bus companies travel from Mississauga to Buffalo?
There are 3 bus lines from Mississauga to Buffalo available for you to search and compare on Wanderu. With 6 daily trips, FlixBus US usually has the most buses running on any given day. Here are some time and price comparisons for all the available options:
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Adirondack Trailways | 1 | 2h 45m | CZK 544.97 |
| FlixBus US | 6 | 5h 5m | CZK 752.03 |
| Greyhound | 2 | 5h 53m | CZK 760.88 |
Adirondack Trailways connects areas in New York such as the Adirondacks and Hudson Valley with New York City, serving a total of 94 cities. Some of its top routes include those going to Albany, Ithaca, and Syracuse. Onboard, Adirondack Trailways vehicles have Wi-Fi for internet connectivity on the move and additional amenities, including power outlets, restrooms, air conditioning, overhead lighting, and reclinable seats with footrests.
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 6 trips per day from Mississauga to Buffalo, and the average ticket for this route costs only CZK 752.03.






Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Mississauga to Buffalo every day, with the average journey taking around 5 hours and 53 minutes to complete. Bus tickets for Greyhound trips to Buffalo usually start from CZK 551.31.






Frequently asked questions about traveling by bus from Mississauga to Buffalo
There are 6 scheduled buses that travel from Mississauga to Buffalo every day, so you have a decent number of options to choose from. This includes 2 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.
Trips per day
6
Direct trips
2
The bus takes an average of 5 hours and 22 minutes to cover the 62 miles from Mississauga to Buffalo. However, the fastest bus only takes 2 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
62
Distance (km)
100
The first bus leaves at 12:10 AM and the last bus leaves at 4:55 PM. To see the times for all buses from Mississauga to Buffalo, enter your specific travel dates in the search bar.
Earliest bus
12:10am
Latest bus
4:55pm
Sunday tends to be the busiest day for buses, as many passengers take the bus to Buffalo at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
Most crowded
Sunday
Least crowded
Thursday
City Information
Buffalo



Buffalo is a great budget destination that will not burn through your pocket. Located just a few hours’ drive away from Niagara Falls, the city serves as a transportation hub for tourists who want to marvel at the sights of the famous landmark. Visitors can either enjoy the tour from a boat, or walk around the section behind the falls themselves. If you opt for a more idyllic and peaceful destination instead, Forest Lawn is a good choice. A beautiful cemetery that is far from the hustle and bustle of the big city, the destination is a perfect spot for a picnic. As the day winds down to an end, don’t hesitate to attend a performance at Shea’s Performing Arts Center, which features lavish interiors as well as amazing Broadway shows.
Buffalo’s chicken wings are the city’s trademark dish, and tourists who wish to grab a bite could do so at Duff’s Famous Wings or Anchor Bar. For a wider selection, The Left Bank is an even better option.
The principal bus station in Buffalo is the Metropolitan Transportation Center downtown. Travelers can catch buses by Greyhound, New York Trailways, Fullington Trailways and Barons Bus Lines from this station. The main Amtrak train station in Buffalo is located on Exchange St not too far from the bus station. Buffalo is served by Amtrak’s Empire Service and Maple Leaf lines. The city’s principal airport is the Buffalo Niagara International Airport, which is located in the suburb area of Cheektowaga. The city is also served by the nearby Niagara Falls International Airport.
Station Information
Where does the bus leave from in Mississauga?
Main departure station: Duke of York Blvd. Bus Stop
Buses to Buffalo leave from 4 stations in Mississauga.
All bus stations in Mississauga:
- Duke of York Blvd. Bus Stop
- Toronto Pearson Airport YYZ Bus Posts
- 4310 Winston Churchill Blvd
- Toronto Pearson Airport YYZ Terminal 1 Gate A
Where does the bus arrive in Buffalo?
Main arrival station: Downtown Terminal - 181 Ellicott St

The Downtown Terminal in Buffalo is the center of bus transportation in the city. The terminal currently serves many intercity bus lines such as Greyhound, FlixBus, Fullington Trailways, Barons Bus Lines, and New York Trailways. The station offers vending machines and even a Tim Horton’s for a taste of Canada’s favorite coffee and donuts. Situated in the heart of downtown Buffalo, travelers can easily access restaurants, hotels, or the Amtrak station on Exchange Street to continue their travels.
All bus stations in Buffalo:
- Downtown Terminal - 181 Ellicott St
- 181 Ellicott Street
Need a return trip from Buffalo to Mississauga?
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