Cheap bus tickets from Orlando to Knoxville
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Bus from Orlando to Knoxville: Journey Information
There are 4 intercity buses per day from Orlando to Knoxville. Traveling by bus from Orlando to Knoxville usually takes around 26 hours and 1 minute, but the fastest FlixBus US bus can make the trip in 15 hours and 50 minutes.
| Distance | 534 mi (859 km) |
| Shortest duration | 15h 50m |
| Cheapest price | $100.47 |
| Trips per day | 0 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |
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Orlando to Knoxville Bus Schedule
There are several bus options that can take you from Orlando to Knoxville:
See more detailsHow much is a bus ticket from Orlando to Knoxville?
Bus tickets for a trip from Orlando to Knoxville cost $106.96 on average. Bus tickets on this route can be a bit expensive due to the length of the trip. But even with a higher price tag, taking the bus is often more affordable than flying to Knoxville. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Orlando to Knoxville by travel date
If you're planning to travel by bus from Orlando to Knoxville in the next month, the average ticket price is expected to range from $85 to $188. The cheapest bus tickets available in the next few weeks are for trips departing on September 18, 2026. If you’re looking to travel to Knoxville this week, bus tickets are available starting at $113.
Average bus ticket prices from Orlando to Knoxville by month
Taking the bus from Orlando to Knoxville is usually cheapest in October, when the average ticket price is only $148. If you're planning to take the bus from Orlando to Knoxville during June, keep in mind that bus ticket prices may be higher than usual, with an average price of $216. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 22 days in advance. This way, you can save up to $142.13 on your bus ticket compared to booking last-minute.
What bus companies travel from Orlando to Knoxville?
There are multiple buses that travel from Orlando to Knoxville, including FlixBus US. Here is what you should know about the 1 most popular bus lines:
| BUS | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 4 | 26h 1m | $219.65 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 4 trips per day from Orlando to Knoxville, and the average ticket for this route costs only $219.65.
Frequently asked questions about traveling by bus from Orlando to Knoxville
There are 4 scheduled buses that travel from Orlando to Knoxville every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.
TRIPS PER DAY
4
DIRECT TRIPS
0
The bus takes an average of 26 hours to cover the 534 miles from Orlando to Knoxville. However, the fastest bus only takes 15 hours and 50 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
DISTANCE (MI)
534
DISTANCE (KM)
859
The first bus leaves at 6:00am and the last bus leaves at 10:55pm. To see the times for all buses from Orlando to Knoxville, enter your specific travel dates in the search bar.
EARLIEST BUS
6:00am
LATEST BUS
10:55pm
Friday is the busiest travel day for buses as people head from Orlando to Knoxville for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
MOST CROWDED
Friday
LEAST CROWDED
Tuesday
City Information
Orlando
Orlando is the Theme Park Capital of the World, thanks to the high density of thrilling parks like Walt Disney World, Universal Studios, SeaWorld, LEGOLAND, Gatorland and more. It's no wonder we rated Orlando the #1 travel destination for families. Family vacation or not, if the highlight of your trip is picking out a wand at Ollivanders in the Wizarding World of Harry Potter or finally meeting Elsa in the Magic Kingdom, you know we won't judge.
Winter Park and Thornton Park – not more theme parks, we promise – are trendy neighborhoods where you can experience some of Orlando's world-class shopping, dining, and craft beer. You can also immerse yourself in some of Florida's unique wildlife at Orlando Wetlands Park, or the more central Lake Eola Park downtown. Orlando enjoys an average of 233 days of sunshine a year, so even though it's one of the cheapest cities to visit over Spring Break, you'll soak up that sweet, sweet sun almost any time of year.
Craving the ocean? Head a few hours outside Orlando for some of Florida's gorgeous beaches like New Smyrna Beach, Cocoa Beach, and the Canaveral National Seashore. Two large airports, as well as many bus and train companies with service in the area, mean that traveling from Orlando to other sunny Florida destinations and beyond is a breeze.
Station Information
Where does the bus leave from in Orlando?
Main departure station: Bus Terminal - 555 N John Young Pkwy
The Bus Terminal at 555 N John Young Pkwy is the primary Greyhound bus station in Orlando, where travelers can catch a bus to other destinations throughout Florida and beyond. The station is located under 3 miles from downtown Orlando and the nearest SunRail station. There is also a Lynx public bus stop which conveniently drops people off right at the Greyhound Bus Terminal. Open 24 hours a day, the bus station provides vending machines if you need a quick bite, and there are also several fast food options within a short walk to fuel up before your trip.
All bus stations in Orlando:
- Bus Terminal - 555 N John Young Pkwy
- The Florida Mall
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Orlando arrive at one main station in Knoxville.
All bus stations in Knoxville:
- Knoxville Bus Station
Need a return trip from Knoxville to Orlando?
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