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Sioux City to La Crosse bus

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Sioux City - La Crosse Bus Schedule

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Journey Information

There are 2 intercity buses per day from Sioux City to La Crosse. Traveling by bus from Sioux City to La Crosse usually takes around 19 hours and 40 minutes, but the fastest Jefferson Lines bus can make the trip in 19 hours and 35 minutes.

Distance275 mi (443 km)
Shortest duration19h 35m
Cheapest price$190.03
Most frequent serviceJefferson Lines
Bus lines1

What bus companies travel from Sioux City to La Crosse?

There is one intercity bus company available to search and book on Wanderu that operates from Sioux City to La Crosse. Jefferson Lines is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.

BusDaily TripsAvg. TimeAvg. Price
Jefferson Lines219h 40m$198.69
  • Jefferson Lines is a well-established intercity bus company with service to some of the Midwest’s top travel destinations. As one of the United States’ largest bus service providers, Jefferson Lines is beloved by students, commuters, and vacationers in America’s heartland. Travel with Jefferson Lines is comfortable thanks to reclining seats, individual climate controls, restrooms, and free WiFi. You can even check the status of your trip with their bus tracker tool. The carrier provides safe, affordable, and reliable service from Sioux City to La Crosse with ticket prices as low as $190.

Frequently Asked Questions

The bus takes an average of 19 hours and 40 minutes to cover the 443 kilometers from Sioux City to La Crosse. However, the fastest bus only takes 19 hours and 35 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Tuesday is usually the day of the week when buses are busiest. If you are planning to travel on a Tuesday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Friday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Friday ticket is the way to go.

The first bus leaves at 6:00pm and the last bus leaves at 6:00pm. To see the times for all buses from Sioux City to La Crosse, enter your specific travel dates in the search bar.

There are usually only 2 buses per day from Sioux City to La Crosse. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.

City Information

La Crosse

La Crosse, WI - LSE-0

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La Crosse, WI - LSE-1

Image credit: Carl Wycoff

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La Crosse, WI - LSE-2

Image credit: Unsplash

A busy college town blessed with lush and beautiful green zones, La Crosse is one of the best places to just chill out and unwind. The city's star attraction is the Grandad Bluff, which offers a panoramic view of the entire city and the Mississippi River. Hiking up the hill will certainly be a challenge, but the view from the top makes it all worthwhile. While staying in the city, don't miss out on the chance to go on a cruise aboard the La Crosse Queen, a replica paddle steamer, and unwind while enjoying the sunset. For some family fun, head over to the Children's Museum of La Crosse.

La Crosse does have a pretty reputable food scene, with a strong focus on beers and cheese curds. For an upscale dining experience with the best local dishes, The Waterfront Restaurant & Tavern is a local favorite that has a stellar reputation. Or head to the Dublin Square Irish Pub & Eatery for a combination of good foods and drinks.

La Crosse is easily accessible by bus or train, and regional flights operate out of the La Crosse Municipal Airport.

Station Information

Where does the bus leave from in Sioux City?

Main departure station: 501 Nebraska St

Most buses depart from the main station in Sioux City.

All bus stations in Sioux City:

  • 501 Nebraska St

Where does the bus arrive in La Crosse?

Main arrival station: University of Wisconsin

These are the two stations where buses may stop when they arrive in La Crosse.

Bus stations in La Crosse:

  • University of Wisconsin

  • 314 Jay St

Get around town with Moovit

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Need a return trip from La Crosse to Sioux City?

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