Lowest Prices
We partner with the top bus & train carriers to bring you the best deals.
Best Travel Options
We help you find & compare the best buses & trains in one place.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
Journey Information
There are 3 intercity buses per day from St Louis to Charleston. Traveling by bus from St Louis to Charleston usually takes around 22 hours and 50 minutes, but the fastest Greyhound bus can make the trip in 20 hours and 20 minutes.
| Distance | 703 mi (1132 km) |
| Shortest duration | 20h 20m |
| Cheapest price | $122.85 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
What bus companies travel from St Louis to Charleston?
There is one intercity bus company available to search and book on Wanderu that operates from St Louis to Charleston. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 3 | 22h 50m | $146.47 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from St Louis to Charleston every day, with the average journey taking around 22 hours and 50 minutes to complete. Bus tickets for Greyhound trips to Charleston usually start from $121.
Frequently Asked Questions
The bus takes an average of 22 hours and 50 minutes to cover the 1132 kilometers from St Louis to Charleston. However, the fastest bus only takes 20 hours and 20 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
"Sunday tends to be the busiest day for buses, as many passengers take the bus to Charleston at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet."
The first bus leaves at 4:00am and the last bus leaves at 6:00pm. To see the times for all buses from St Louis to Charleston, enter your specific travel dates in the search bar.
City Information
St Louis
Image credit: Unsplash
Image credit: Unsplash
Image credit: Unsplash
St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.
Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.
Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.
The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.
Charleston
An idyllic city with quaint moss-covered and time-washed buildings, Charleston offers plenty of scenic sights and culturally significant destinations to explore. The highlights of this amazing city are its cobblestone streets and hauntingly beautiful mansions (some are even rumored to be actually haunted). The best way to enjoy these timeless relics is to take a walking tour around town, with or without a local guide. As you enjoy your walking tour, don’t miss out on the chance to explore The Battery, which features some of the most photogenic spots in the entire city. This quarter used to be the center of all maritime activities in the city, but it is now a famous tourist area. The nearby White Point Garden, which houses interesting Civil War-era relics, is also a great destination.
Charleston is a top foodie destination, being quite famous for its Southern staples. The best places to indulge in these Southern delicacies are Husk and Magnolias. If you crave some seafood, Hyman’s Seafood is a local favorite. Plus, Charleston's nightlife makes it a great destination for bachelorette parties.
The main bus station in the city is located on Rivers Ave. The city’s main airport is the Charleston International Airport, 12 miles northwest of downtown.
Station Information
Where does the bus leave from in St Louis?
Image credit: Chris Yunker
Link to image attributionMain departure station: Gateway Station - 430 S 15th St
Gateway Station opened in 2008 to consolidate St Louis’ transportation services into one central hub. The station’s award-winning design includes a pedestrian walkway with expansive colored glass windows overlooking the train tracks. Perfectly located in the heart of downtown St Louis, the station is surrounded by bars, restaurants, and hotels and is just a few blocks from Busch Stadium and the iconic Gateway Arch. Amenities inside the station include free Wifi, a food court, and a lounge for Amtrak’s First Class passengers. Gateway Station is a major stop for intercity bus service, several Amtrak train lines, and the city’s MetroLink which can connect you with the St Louis Lambert International Airport in just 30 minutes.
All bus stations in St Louis:
Gateway Station - 430 S 15th St
Where does the bus arrive in Charleston?
Main arrival station: Greyhound Station - 3610 Dorchester Rd
All buses from St Louis arrive at one main station in Charleston.
Bus stations in Charleston:
Greyhound Station - 3610 Dorchester Rd
Get around town with Moovit
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free and with no additional fees. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
Book buses and trains on the go with the Wanderu app.
Download our app and snag the best travel deals across North America & Europe.Learn more