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Isilines is a popular bus company offering very affordable ticket options to top travel destinations. You will always find the cheapest Isilines tickets by searching Wanderu.com. Overall, Isilines serves 1,025 bus routes, connecting 66 cities in 1 countries. To cover all these routes Isilines runs an average of 638 trips per day and 19,398 trips per month. These bus trips range in price from $5.91 to $201.97 based on a variety of factors.