Cheap coach tickets from Knoxville to Chicago
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Knoxville to Chicago Coach Timetable
Coach from Knoxville to Chicago: Journey Information
There are 7 intercity coaches per day from Knoxville to Chicago. Traveling by coach from Knoxville to Chicago usually takes around 17 hours and 17 minutes, but the fastest Greyhound coach can make the trip in 14 hours and 40 minutes.
| Distance | 455 mi (732 km) |
| Shortest duration | 14h 40m |
| Cheapest price | US$59.96 |
| Most frequent service | Greyhound |
| Coach lines | 1 |

How much is a coach ticket from Knoxville to Chicago?
Bus tickets for a trip from Knoxville to Chicago cost US$116.62 on average. Bus tickets on this route can be a bit expensive due to the length of the trip. But even with a higher price tag, taking the bus is often more affordable than flying to Chicago. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average coach ticket prices from Knoxville to Chicago by travel date
Over the next four weeks, the average price of bus tickets from Knoxville to Chicago is expected to be between US$106 and US$161. The cheapest day to travel in the next month is 11 November 2025, when tickets are available for 11 November 2025. The cheapest bus tickets available in the next week start at just US$106.
Monthly average prices
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 18 days in advance. This way, you can save up to US$80.45 on your bus ticket compared to booking last-minute.
What coach companies travel from Knoxville to Chicago?
There is one intercity bus company available to search and book on Wanderu that operates from Knoxville to Chicago. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Coach | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 7 | 17h 17m | US$126.23 |
Greyhound is the largest nationwide coach carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 7 bus trips from Knoxville to Chicago every day, with the average journey taking around 17 hours and 17 minutes to complete. Bus tickets for Greyhound trips to Chicago usually start from US$60.
Frequently asked questions about traveling by coach from Knoxville to Chicago
The coach takes an average of 17 hours and 17 minutes to cover the 455 miles from Knoxville to Chicago. However, the fastest coach only takes 14 hours and 40 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual coach may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Thursday is usually the day of the week when coaches are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Tuesday is typically the least busy day for coach travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
The first coach leaves at 18:00 and the last coach leaves at 22:00. To see the times for all coaches from Knoxville to Chicago, enter your specific travel dates in the search bar.
City Information
Chicago



Known for its innovative architecture, cultural contributions to jazz and house music, and of course that irresistible deep-dish pizza, the many sights and experiences in Chicago make it one of the best urban vacation destinations for millennials and a top destination in Illinois.
You can't beat the views of the city and Lake Michigan from the SkyDeck in the Willis Tower; at over 1,300 feet, this is the highest observation deck in the U.S. Snap that classic selfie with the Bean in Millennium Park, then wander the many museums in nearby Grant Park. Navy Pier is a popular tourist hotspot for its parks, restaurants, and attractions right on Lake Michigan, and baseball fans will find paradise in Wrigleyville, home to the Chicago Cubs' Wrigley Field and sports bars galore.
Chicago's enormous parks offer plentiful opportunities for outdoor activities in gorgeous urban settings. Many companies offer kayak rentals or boat tours on the Chicago River, with special tours running on Saint Patrick's Day, when the entire river is dyed green. When you’re ready to buy some souvenirs from your epic trip, hit the big brand stores on the Magnificent Mile, or shop local in neighborhoods like Andersonville and Wicker Park. And don't miss the chance to laugh until you cry at The Second City comedy theater, famous for launching the careers of comedians like Tina Fey and Stephen Colbert.
Chicago is one of the biggest transportation hubs in the Midwest, and provides easy access to nearby destinations ideal for day trips, as well as international travel from two airports. Thanks to plenty of bus and train stations throughout the city, getting to the Windy City is a breeze.
Station Information
Where does the coach leave from in Knoxville?
Main departure station: Knoxville Bus Station
Most coaches depart from the main station in Knoxville.
All coach stations in Knoxville:
Knoxville Bus Station
Where does the coach arrive in Chicago?

Image credit: Jeramey Jannene
Link to image attributionMain arrival station: Bus Station - 630 W Harrison St
Coaches arrive in Chicago at 3 stations, depending on which coach line you are traveling with.
Coach stations in Chicago:
Bus Station - 630 W Harrison St
Dan Ryan Bus Station
Chicago Train Station Bus Stop
Get around town with Moovit
Need a return trip from Chicago to Knoxville?
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