Cheap bus tickets from Harrisburg to San Antonio
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Harrisburg to San Antonio Bus Schedule
Bus from Harrisburg to San Antonio: Journey Information
There is one daily bus from Harrisburg to San Antonio. Traveling by bus from Harrisburg to San Antonio usually takes around 57 hours and 45 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 1430 mi (2302 km) |
| Shortest duration | 57h 45m |
| Cheapest price | $411.43 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Harrisburg to San Antonio?
There is one intercity bus company available to search and book on Wanderu that operates from Harrisburg to San Antonio. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 2d 9h 45m | $411.43 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Harrisburg to San Antonio, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Harrisburg to San Antonio
The bus takes an average of 57 hours and 45 minutes to cover the 1430 miles from Harrisburg to San Antonio. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from Harrisburg to San Antonio. It leaves the station in Harrisburg at 2:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
There is usually only one bus per day from Harrisburg to San Antonio. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.
Need more travel options? Consider taking the train from Harrisburg to San Antonio; ticket prices start at $437.00.
City Information
Harrisburg



As the capital city of Pennsylvania, Harrisburg offers numerous historic buildings with impressive architecture that will leave you in awe. Among the most impressive ones is the state’s Capitol Complex itself. With a dome that reminisces St. Peter’s Basilica in Rome, the building features as many as 475 rooms filled with exquisite artworks and statues. History fans should also consider visiting the State Museum of Pennsylvania, which follows the history of the state from the beginning of time to this day. Another must-see destination is the National Civil War Museum, which is one of the largest museums dedicated to the Civil War. If too many history lessons stress you out, a cruise along the Susquehanna River on the Pride of the Susquehanna Riverboat will definitely help you unwind.
Harrisburg’s grilled dishes are some of the most famous staples in the city, and among the best establishments is Progress Grill, which has been serving customers since the late 1940s. For some really creative pizzas, The Pizza Grille will be a good choice.
The Harrisburg Transportation Center is the central hub for intercity travel. At the lower level, you can catch a bus by Greyhound, Jefferson Lines or Fullington Trailways to other Pennsylvanian cities such as Allentown and Philadelphia. Travelers can also take Amtrak trains to popular destinations like New York and Philadelphia on a daily basis. The city’s principal airport is Harrisburg International Airport, which is located in Middletown, southeast of the city.
San Antonio

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
San Antonio is a fast-growing city located in the southwest corner of the Texas Triangle. In addition to the alluring year-round warm weather, San Antonio offers a blend of rich history with contemporary attractions and cuisine.
If there's one thing to remember from your trip to San Antonio, it’s the Alamo! This 18th century fortress is one of five Spanish missions in the San Antonio Missions National Historical Park, all of which are connected by a scenic hiking and biking trail. If history isn't your thing, the River Walk along the San Antonio River is a much livelier spot. This shaded path is lined with shops and restaurants, and you could spend an entire day strolling, shopping, and eating along the river. Don't sleep on the riverside bars, either – San Antonio is one of the cheapest drinking cities in the U.S. so you can bar-hop to your heart’s (and your wallet’s) delight.
Traveling with little ones? San Antonio is home to the San Antonio Zoo, SeaWorld, and Six Flags Fiesta Texas, any one of which will provide a thrilling adventure with no screen time required. Visitors of all ages will find treasures at Historic Market Square, the largest Mexican market in the U.S., where handcrafted art from local artisans is available alongside authentic Mexican food.
San Antonio is one of the biggest cities in the Lone Star State, so it is very easy to travel to other Texas destinations like Austin, Houston, and Dallas by bus or by train, or to destinations farther afield through the San Antonio International Airport.
Station Information
Where does the bus leave from in Harrisburg?
Main departure station: Harrisburg Transportation Center
Most buses depart from the main station in Harrisburg.
All bus stations in Harrisburg:
Harrisburg Transportation Center
Where does the bus arrive in San Antonio?
Main arrival station: Pearl District - 612 Avenue A
All buses from Harrisburg arrive at one main station in San Antonio.
All bus stations in San Antonio:
Pearl District - 612 Avenue A
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