|Fastest time||16h 15m|
|Trips per day||5|
Book Greyhound from St Louis to Buffalo from $92.47. There are 5 Greyhound schedules from St Louis to Buffalo and you can expect on average to pay $141.34 for a Greyhound ticket to Buffalo. In St Louis, Greyhound departs to Buffalo from Gateway Station - 430 S 15th St and 1 other station. In Buffalo, Greyhound arrives at Downtown Term - 181 Ellicott St and 1 other station.
An average trip on Greyhound from St Louis to Buffalo takes 17 hours and 38 minutes, while the fastest available Greyhound trip will get you to Buffalo in 16 hours and 15 minutes,
On weekends, Greyhound offers 5 trips per day and you could expect to pay $143.55 for a weekend getaway trip to Buffalo.