Cheap bus tickets from Sisseton to Sioux City
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Sisseton to Sioux City Bus Schedule
Bus from Sisseton to Sioux City: Journey Information
There is one daily bus from Sisseton to Sioux City. Traveling by bus from Sisseton to Sioux City usually takes around 5 hours and 20 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 221 mi (356 km) |
| Shortest duration | 5h 20m |
| Cheapest price | $103.00 |
| Most frequent service | Jefferson Lines |
| Bus lines | 1 |

What bus companies travel from Sisseton to Sioux City?
There is one intercity bus company available to search and book on Wanderu that operates from Sisseton to Sioux City. Jefferson Lines is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Jefferson Lines | 1 | 5h 20m | $103.00 |
Book Jefferson Lines from Sisseton to Sioux City from $103. Typically there is one Jefferson Lines schedule per day from Sisseton to Sioux City and you can expect on average to pay for a Jefferson Lines ticket to Sioux City. In Sisseton, Jefferson Lines departs to Sioux City from Dakota Connection Center . In Sioux City, Jefferson Lines arrives at 501 Nebraska St .
An average trip on Jefferson Lines from Sisseton to Sioux City takes 5 hours and 20 minutes .
Frequently asked questions about traveling by bus from Sisseton to Sioux City
The bus takes an average of 5 hours and 20 minutes to cover the 221 miles from Sisseton to Sioux City. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from Sisseton to Sioux City. It leaves the station in Sisseton at 3:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Station Information
Where does the bus leave from in Sisseton?
Main departure station: Dakota Connection Center
Most buses depart from the main station in Sisseton.
All bus stations in Sisseton:
Dakota Connection Center
Where does the bus arrive in Sioux City?
Main arrival station: 501 Nebraska St
All buses from Sisseton arrive at one main station in Sioux City.
All bus stations in Sioux City:
501 Nebraska St
Get around town with Moovit
Need a return trip from Sioux City to Sisseton?
Search Bus Tickets
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
- Bus Tickets
- United States
- Iowa
- Sioux City
- Sisseton to Sioux City






