Cheap bus tickets from Lafayette to St Louis
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Lafayette to St Louis Bus Schedule
Bus from Lafayette to St Louis: Journey Information
There are 3 intercity buses per day from Lafayette to St Louis. Traveling by bus from Lafayette to St Louis usually takes around 8 hours and 41 minutes, but the fastest Greyhound bus can make the trip in 6 hours and 45 minutes.
Distance | 216 mi (348 km) |
Shortest duration | 6h 45m |
Cheapest price | €26.79 |
Most frequent service | Greyhound |
Bus lines | 2 |

How much is a bus ticket from Lafayette to St Louis?
Bus tickets for a trip from Lafayette to St Louis cost €40.85 on average. Tickets cheaper than €40.85 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Lafayette to St Louis by travel date
Over the next four weeks, the average price of bus tickets from Lafayette to St Louis is expected to be between €35 and €60. The cheapest day to travel in the next month is July 9, 2025, when tickets are available for July 9, 2025. The cheapest bus tickets available in the next week start at just €36.
Monthly avg. prices
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 28 days in advance. This way, you can save up to €35.24 on your bus ticket compared to booking last-minute.
What bus companies travel from Lafayette to St Louis?
There are two bus lines that have daily service from Lafayette to St Louis that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 3 scheduled trips per day.
Bus | Daily Trips | Avg. Time | Avg. Price |
---|---|---|---|
FlixBus US | 1 | 10h 24m | €52.95 |
Greyhound | 3 | 8h 41m | €47.86 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Lafayette to St Louis, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Lafayette to St Louis every day, with the average journey taking around 8 hours and 41 minutes to complete. Bus tickets for Greyhound trips to St Louis usually start from €27.
Frequently asked questions about traveling by bus from Lafayette to St Louis
The bus takes an average of 8 hours and 41 minutes to cover the 216 miles from Lafayette to St Louis. However, the fastest bus only takes 6 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Saturday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Saturday ticket is the way to go.
The first bus leaves at 6:00am and the last bus leaves at 6:00pm. To see the times for all buses from Lafayette to St Louis, enter your specific travel dates in the search bar.
There are 3 scheduled buses that travel from Lafayette to St Louis every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.
Need more travel options? Consider taking the train from Lafayette, IN to St Louis, MO; ticket prices start at €104.65.
City Information
Lafayette

Image credit: Unsplash

Image credit: Pixabay

Image credit: Unsplash
Lafayette, a quaint college town with a vibrant history, is a superb destination for fans of history and old buildings. The city's historic old quarter is a beautiful sight to behold, with some buildings dating back to the 19th century. A walk around this quarter will bring you back to the early days of the American Industrial Revolution. Don't miss out on the chance to visit Fort Ouiatenon, the first European fortified settlement in the area now called Indiana. If you are looking for a spot to enjoy a picnic with your friends and your family, head to historic Prophetstown State Park for plenty of activities; we're talking a water park, unique wildlife observation, camping, and a working farm dating back to the 1920s.
Lafayette's food scene offers a good mix of traditional dishes and modern ones. If you wish to enjoy genuine local specialties, South Street Smokehouse offers amazing homestyle dishes. For those who just can't have enough local pizzas, stop by Arni's, a pizzeria that has been around for more than 40 years.
Travel to Lafayette is easy thanks to multiple bus lines and the Amtrak Cardinal line, which runs through the city. The nearest major airport is about 60 miles away in Indianapolis, so ground travel is definitely your friend for this destination.
St Louis

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.
Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.
Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.
The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.
Station Information
Where does the bus leave from in Lafayette?
Main departure station: Parking Lot next to CityBus Center
Most buses depart from the main station in Lafayette.
All bus stations in Lafayette:
Parking Lot next to CityBus Center
Where does the bus arrive in St Louis?
Main arrival station: Gateway Station - 430 S 15th St
All buses from Lafayette arrive at one main station in St Louis.
All bus stations in St Louis:
Gateway Station - 430 S 15th St
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