Cheap bus tickets from Palermo to Rome

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Bus from Palermo to Rome: Journey Information

There are 6 intercity buses per day from Palermo to Rome. Travelling by bus from Palermo to Rome usually takes around 16 hours and 50 minutes, but the fastest Autoservizi Salemi bus can make the trip in 12 hours and 15 minutes.

Distance: 266 mi (427 km)
Shortest duration: 12h 15m
Cheapest price: $30.53
Trips per day: 6
Most frequent service: FlixBus
Bus lines: 2

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Palermo to Rome Bus Schedule

There are several bus options that can take you from Palermo to Rome:

See more details

How much is a bus ticket from Palermo to Rome?

Bus tickets for a trip from Palermo to Rome cost about $96 when you book at the cheapest time, 4 days ahead. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.

Average bus ticket prices from Palermo to Rome by travel date

If you're planning to travel by bus from Palermo to Rome in the next month, the average ticket price is expected to range from $74 to $116. The cheapest bus tickets available in the next few weeks are for trips departing on November 7, 2026. If you’re looking to travel to Rome this week, bus tickets are available starting at $74.

Average bus ticket prices from Palermo to Rome by month

Taking the bus from Palermo to Rome is usually cheapest in October, when the average ticket price is only $106. If you're planning to take the bus from Palermo to Rome during August, keep in mind that bus ticket prices may be higher than usual, with an average price of $149. However, booking your trip in advance can help you score a ticket at a better price.

Prices as travel date approaches

Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. Booking in advance is the best way to find cheap bus tickets, even if it’s only by a few days.

What bus companies travel from Palermo to Rome?

There are two bus lines that have daily service from Palermo to Rome that you can compare and book on Wanderu. Of these two carriers, FlixBus usually offers more choice, with 5 scheduled trips per day.

Bus	Daily Trips	Avg. Time	Avg. Price
Autoservizi Salemi	1	12h 15m	$79.54
FlixBus	5	17h 49m	$109.25

Autoservizi Salemi is an Italian bus company that travels the length of the Italian peninsula daily. Some notable routes include stops in Milan, Florence, Bologna, Marsala, and Palermo. Their modern buses have excellent amenities including air conditioning, power outlets, washrooms, WiFi, and snacks and drinks for sale.
First launched in Germany in 2013, FlixBus has become one of the largest intercity bus companies in Europe. Its fleet travels through nearly every country in Europe, including the U.K. FlixBus operates an average of 5 trips from Palermo to Rome, and usually makes the trip in about 17 hours and 49 minutes. On your trip, you'll enjoy Wi-Fi and live GPS, as well as washrooms, air conditioning, and power outlets.

Frequently asked questions about travelling by bus from Palermo to Rome

There are 6 scheduled buses that travel from Palermo to Rome every day, so you have a decent number of options to choose from. This includes 2 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.

Trips per day

Direct trips

The bus takes an average of 16 hours and 50 minutes to cover the 427 kilometres from Palermo to Rome. However, the fastest bus only takes 12 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Distance (mi)

266

Distance (km)

427

The first bus leaves at 11:05 a.m. and the last bus leaves at 9:10 p.m. To see the times for all buses from Palermo to Rome, enter your specific travel dates in the search bar.

Earliest bus

11:05am

Latest bus

9:10pm

Tuesday is usually the day of the week when buses are busiest. If you are planning to travel on a Tuesday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.

Most crowded

Tuesday

Least crowded

Monday

City Information

Rome

Rome is a city rich in cultural heritage, as well as one of the most romantic destinations in Europe. To fully understand the city’s extraordinary history, visitors should take the time to visit the Capitoline Museums, where the collections include hundreds of sculptures as well as the Capitoline Wolf, the symbol of Rome itself. The famous Trevi’s Fountain is also on the must-see list of many travellers. Boasting an amazing baroque design with mythological motifs, the fountain is one of the most photogenic spots in the city, and it is located near the principal shopping area. If you wish to check out some of the city’s most iconic structures, head over to the Sistine Chapel, which houses the famous fresco by Michelangelo.

Rome is every foodie’s heaven. As you explore the city’s food scene, don’t hesitate to take the chance to try out a local specialty, artichokes. The best place to try these out is at Nonna Betta. For those who want to try the famous Roma coffee, Caffe Sant'Eustachio might be the right spot.

The principal train station in Rome is the Termini station. The main bus station is Roma Tiburtina. The city’s air services are fulfilled by three airports: Leonardo da Vinci International Airport, Rome Ciampino Airport, and Roma-Urbe, of which the Leonardo da Vinci International Airport is the largest.

Station Information

Where does the bus leave from in Palermo?

Main departure station: Via Tommaso Fazello - Autostazione

Most buses depart from the main station in Palermo.

All bus stations in Palermo:

Via Tommaso Fazello - Autostazione

Where does the bus arrive in Rome?

Main arrival station: Largo Guido Mazzoni

Rome's main long-distance bus station, known as Autostazione Tiburtina, is located on Largo Guido Mazzoni in the northeast of the city. The modern, state-of-the-art facility has several small food outlets, washrooms, and left luggage facilities. Bus companies like FlixBus and RegioJet operate routes from Tiburtina to destinations including Venice and Prague. It can be accessed via the city's metro line B and is just a short walk to Roma Tiburtina railway station. Several hotels, bars, and restaurants line the nearby Via Tiburtina for the perfect welcome to the Eternal City.

All bus stations in Rome:

Largo Guido Mazzoni
Largo Mazzoni Guido Bus Station
Ciampino Airport
Via Vincenzo Giudice

Need a return trip from Rome to Palermo?

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