Cheap bus tickets from Knoxville, TN to Cleveland, OH
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Bus from Knoxville, TN to Cleveland, OH: Journey Information
There is one daily bus from Knoxville, TN to Cleveland, OH. Travelling by bus from Knoxville, TN to Cleveland, OH usually takes around 12 hours and 25 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
- Distance
- 401 mi (645 km)
- Shortest duration
- 12h 25m
- Cheapest price
- $104.60
- Trips per day
- 1
- Most frequent service
- Greyhound
- Bus lines
- 1
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Knoxville, TN to Cleveland, OH Bus Schedule

There are several bus options that can take you from Knoxville, TN to Cleveland, OH:
See more detailsHow much is a bus ticket from Knoxville, TN to Cleveland, OH?
Bus tickets for a trip from Knoxville, TN to Cleveland, OH cost about $107 when you book at the cheapest time, 22 days ahead. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Knoxville, TN to Cleveland, OH by travel date
If you're planning to travel by bus from Knoxville, TN to Cleveland, OH in the next month, the average ticket price is expected to range from $116 to $148. The cheapest bus tickets available in the next few weeks are for trips departing on November 7, 2026. If you’re looking to travel to Cleveland, OH this week, bus tickets are available starting at $116.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 22 days in advance. This way, you can save up to $97.15 on your bus ticket compared to booking last-minute.
What bus companies travel from Knoxville, TN to Cleveland, OH?
There is one intercity bus company available to search and book on Wanderu that operates from Knoxville, TN to Cleveland, OH. Greyhound is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 1 | 12h 25m | $150.93 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trip from Knoxville, TN to Cleveland, OH every day, with the average journey taking around 12 hours and 25 minutes to complete. Bus tickets for Greyhound trips to Cleveland, OH usually start from $104.60.






Frequently asked questions about travelling by bus from Knoxville, TN to Cleveland, OH
There is usually only one bus per day from Knoxville, TN to Cleveland, OH. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.
Trips per day
1
Direct trips
0
The bus takes an average of 12 hours and 25 minutes to cover the 645 kilometres from Knoxville, TN to Cleveland, OH. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
401
Distance (km)
645
There is usually only one bus per day from Knoxville, TN to Cleveland, OH. It leaves the station in Knoxville, TN at 10:00 p.m. each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
Earliest bus
10:00pm
Latest bus
10:00pm
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
Most crowded
Thursday
Least crowded
Monday
City Information
Cleveland



An industrial powerhouse in the past eras, Cleveland offers to the world more than just LeBron James and Halle Berry. Unlike most other big cities, Cleveland still retains its quaint small-town feel, especially as you wander around the Cleveland Metroparks, a system of 21,000 acres of pure nature. For nature lovers, the Cleveland Botanical Garden provides a treasure trove of botanical knowledge and rare plant species. Another must-not-miss spot is the Rock & Roll Hall of Fame, which features exhibitions on the greatest legends such as Jimi Hendrix, The Beatles, etc.
For foodies, Cleveland truly is a mecca. The city boasts an array of top chefs and high-class establishments that can bring you an unforgettable experience. For authentic American classics, Slyman’s Deli has everything you need. If you are looking for a more diverse option, head to Momocho for some mouth-watering Mexican indulgences.
Cleveland’s main bus station is located just behind the Playhouse Square Parking Garage in the Theater District. The local Amtrak train station is also located downtown not too far from the bus station. The principal airport in the city is the Cleveland Hopkins International Airport, which sits 9 miles southwest of Downtown and is located next to the Glenn Research Center.
Station Information
Where does the bus leave from in Knoxville, TN?
Main departure station: Knoxville Bus Station
Most buses depart from the main station in Knoxville, TN.
All bus stations in Knoxville, TN:
- Knoxville Bus Station
Where does the bus arrive in Cleveland, OH?
Main arrival station: E. 12th between Rockwell and St. Clair
All buses from Knoxville, TN arrive at one main station in Cleveland, OH.
All bus stations in Cleveland, OH:
- E. 12th between Rockwell and St. Clair
Need a return trip from Cleveland, OH to Knoxville, TN?
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