Cheap bus tickets from Philadelphia, PA to Florence, SC

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Bus from Philadelphia, PA to Florence, SC: Journey Information

There are 4 intercity buses per day from Philadelphia, PA to Florence, SC. Travelling by bus from Philadelphia, PA to Florence, SC usually takes around 12 hours and 59 minutes, but the fastest FlixBus US bus can make the trip in 11 hours and 15 minutes.

Distance: 471 mi (759 km)
Shortest duration: 11h 15m
Cheapest price: $104.03
Trips per day: 4
Most frequent service: Greyhound
Bus lines: 2

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Philadelphia, PA to Florence, SC Bus Schedule

Is it better to travel by bus or train from Philadelphia, PA to Florence, SC?

There are usually 4 daily train trips available from Philadelphia, PA to Florence, SC.

	Bus	Train
Avg. Price	Avg. Price$178.56Cheaper	Avg. Price$265.45
Daily Trips	Daily Trips4	Daily Trips4
Duration	Duration12h 59m	Duration11h 58mFaster

There are several bus options that can take you from Philadelphia, PA to Florence, SC:

See more details

How much is a bus ticket from Philadelphia, PA to Florence, SC?

Bus tickets for a trip from Philadelphia, PA to Florence, SC cost about $115 when you book at the cheapest time, 25 days ahead. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.

Average bus ticket prices from Philadelphia, PA to Florence, SC by travel date

If you're planning to travel by bus from Philadelphia, PA to Florence, SC in the next month, the average ticket price is expected to range from $109 to $184. The cheapest bus tickets available in the next few weeks are for trips departing on November 17, 2026. If you’re looking to travel to Florence, SC this week, bus tickets are available starting at $137.

Average bus ticket prices from Philadelphia, PA to Florence, SC by month

Taking the bus from Philadelphia, PA to Florence, SC is usually cheapest in September, when the average ticket price is only $124. If you're planning to take the bus from Philadelphia, PA to Florence, SC during June, keep in mind that bus ticket prices may be higher than usual, with an average price of $205. However, booking your trip in advance can help you score a ticket at a better price.

Prices as travel date approaches

Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 25 days in advance. This way, you can save up to $139.04 on your bus ticket compared to booking last-minute.

What bus companies travel from Philadelphia, PA to Florence, SC?

There are two bus lines that have daily service from Philadelphia, PA to Florence, SC that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 2 scheduled trips per day.

Bus	Daily Trips	Avg. Time	Avg. Price
FlixBus US	2	11h 35m	$188.36
Greyhound	2	14h	$171.47

FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Philadelphia, PA to Florence, SC, and the average ticket for this route costs only $188.36.
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Philadelphia, PA to Florence, SC every day, with the average journey taking around 14 hours to complete. Bus tickets for Greyhound trips to Florence, SC usually start from $104.03.

Frequently asked questions about travelling by bus from Philadelphia, PA to Florence, SC

There are 4 scheduled buses that travel from Philadelphia, PA to Florence, SC every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey. Need more travel options? Consider taking the train from Philadelphia, PA to Florence, SC; ticket prices start at $116.

Trips per day

Direct trips

The bus takes an average of 12 hours and 59 minutes to cover the 759 kilometres from Philadelphia, PA to Florence, SC. However, the fastest bus only takes 11 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Distance (mi)

471

Distance (km)

759

The first bus leaves at 12:05 a.m. and the last bus leaves at 10:00 p.m. To see the times for all buses from Philadelphia, PA to Florence, SC, enter your specific travel dates in the search bar.

Earliest bus

12:05am

Latest bus

10:00pm

With many people travelling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.

Most crowded

Wednesday

Least crowded

Monday

City Information

Philadelphia

We may feel a little bit more than just brotherly love for Philadelphia, a city steeped in history and culture. Where else can you channel your inner Rocky Balboa on his epic run, and later enjoy an authentic Philly cheesesteak as a reward?

Philadelphia’s affordability (especially compared to other East Coast cities) is just one of many reasons it is among Wanderu’s best destinations for college students. Another reason is how much there is to do! Early American history takes precedence at Independence Hall and the Liberty Bell, while museums abound on Benjamin Franklin Parkway, sometimes called the most artistic mile in the city. Head to Reading Terminal Market to fuel up for a night hitting the bars, clubs, and live music joints that line South Street.

Philadelphia is a major hub for both Greyhound and Amtrak, and its 30th Street Station is one of the busiest stations in the country. The plentitude of ground travel and the nearby Philadelphia International Airport make this exciting city very easily accessible, even on a budget.

Florence

Florence is a hidden gem in the northeast of South Carolina. Though best known for its history as a significant railway hub, Florence is a modern city with activities and sights to fill a weekend getaway or a longer vacation.

Every November, Florence goes nuts during the SC Pecan Music and Food Festival, an event hosted downtown to celebrate the beloved pecan. If you're in town during the festival, check out the car show, live music, half marathon, and other associated events to get to know Florence locals and culture.

Florence is a year-round destination for outdoor recreation. Golf is a favourite among Florence residents, so upgrade from mini-golf and try the real thing. Traces Golf Club welcomes golfers of all skill levels, don't worry. Don't leave Florence without spending a day at Lynches River County Park, the starting point of the 66-mile South Carolina Revolutionary Rivers Trail. You can kayak or canoe throughout the county, following the swampy path that allowed American patriots to evade British troops in the American Revolution.

Florence Regional Airport operates limited flights to connect to Charlotte, but most paths to Florence involve some kind of ground travel. Amtrak's Palmetto and Silver Service trains stop in Florence, with connections to New York and Washington to the north and Orlando and Miami to the south. Greyhound and Southeastern Stages offer intercity bus service to Florence that connects the city to other destinations throughout the South.

Station Information

Where does the bus leave from in Philadelphia, PA?

Main departure station: Philadelphia Bus Terminal

Buses to Florence, SC leave from 3 stations in Philadelphia, PA.

All bus stations in Philadelphia, PA:

Philadelphia Bus Terminal
Philadelphia (Bus Terminal)
Park and Ride off Matthews Rd

Where does the bus arrive in Florence, SC?

Main arrival station: Florence

Buses arrive in Florence, SC at 3 stations, depending on which bus line you are travelling with.

All bus stations in Florence, SC:

Florence
611 S Irby St
2301 W Lucas St (TA Gas Station)

Need a return trip from Florence, SC to Philadelphia, PA?

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