Cheap bus tickets from Florence, SC to Tampa, FL

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Bus from Florence, SC to Tampa, FL: Journey Information

There are 2 intercity buses per day from Florence, SC to Tampa, FL. Travelling by bus from Florence, SC to Tampa, FL usually takes around 1 day and 13 minutes, but the fastest FlixBus US bus can make the trip in 12 hours and 10 minutes.

Distance
460 mi (740 km)
Shortest duration
12h 10m
Cheapest price
$116.59
Trips per day
2
Most frequent service
FlixBus US
Bus lines
1

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Florence, SC to Tampa, FL Bus Schedule

Is it better to travel by bus or train from Florence, SC to Tampa, FL?

There are usually 2 daily train trips available from Florence, SC to Tampa, FL.

Bus
Train
Avg. Price$165.92CheaperAvg. Price$182.08
Daily Trips2Daily Trips2
Duration24h 13mDuration14h 16mFaster
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How much is a bus ticket from Florence, SC to Tampa, FL?

Bus tickets for a trip from Florence, SC to Tampa, FL cost about $145 when you book at the cheapest time, 8 days ahead. Bus tickets on this route can be a bit expensive due to the length of the trip. But even with a higher price tag, taking the bus is often more affordable than flying to Tampa, FL. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.

Average bus ticket prices from Florence, SC to Tampa, FL by travel date

$210$140$70NovNov

If you're planning to travel by bus from Florence, SC to Tampa, FL in the next month, the average ticket price is expected to range from $123 to $207. The cheapest bus tickets available in the next few weeks are for trips departing on November 14, 2026. If you’re looking to travel to Tampa, FL this week, bus tickets are available starting at $145.

Average bus ticket prices from Florence, SC to Tampa, FL by month

$250$200$150$100$50JFMAMJJASOND

Taking the bus from Florence, SC to Tampa, FL is usually cheapest in September, when the average ticket price is only $147. If you're planning to take the bus from Florence, SC to Tampa, FL during February, keep in mind that bus ticket prices may be higher than usual, with an average price of $229. However, booking your trip in advance can help you score a ticket at a better price.

Prices as travel date approaches

$225$180$135$90$450

Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 8 days in advance. This way, you can save up to $65.57 on your bus ticket compared to booking last-minute.

What bus companies travel from Florence, SC to Tampa, FL?

There is one intercity bus company available to search and book on Wanderu that operates from Florence, SC to Tampa, FL. FlixBus US is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US224h 13m$165.92
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Florence, SC to Tampa, FL, and the average ticket for this route costs only $165.92.

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Frequently asked questions about travelling by bus from Florence, SC to Tampa, FL

There are usually only 2 buses per day from Florence, SC to Tampa, FL. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip. Need more travel options? Consider taking the train from Florence, SC to Tampa, FL; ticket prices start at $138.

Trips per day

2

Direct trips

0

The bus takes an average of 1 day and 13 minutes to cover the 740 kilometres from Florence, SC to Tampa, FL. However, the fastest bus only takes 12 hours and 10 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Distance (mi)

460

Distance (km)

740

The first bus leaves at 12:05 a.m. and the last bus leaves at 5:45 a.m. To see the times for all buses from Florence, SC to Tampa, FL, enter your specific travel dates in the search bar.

Earliest bus

12:05am

Latest bus

5:45am

Because many passengers travel from Florence, SC to Tampa, FL at the beginning of the work week, Monday is usually the busiest day for buses. If you are planning to travel on a Monday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.

Most crowded

Monday

Least crowded

Tuesday

City Information

Florence

Florence is a hidden gem in the northeast of South Carolina. Though best known for its history as a significant railway hub, Florence is a modern city with activities and sights to fill a weekend getaway or a longer vacation.

Every November, Florence goes nuts during the SC Pecan Music and Food Festival, an event hosted downtown to celebrate the beloved pecan. If you're in town during the festival, check out the car show, live music, half marathon, and other associated events to get to know Florence locals and culture.

Florence is a year-round destination for outdoor recreation. Golf is a favourite among Florence residents, so upgrade from mini-golf and try the real thing. Traces Golf Club welcomes golfers of all skill levels, don't worry. Don't leave Florence without spending a day at Lynches River County Park, the starting point of the 66-mile South Carolina Revolutionary Rivers Trail. You can kayak or canoe throughout the county, following the swampy path that allowed American patriots to evade British troops in the American Revolution.

Florence Regional Airport operates limited flights to connect to Charlotte, but most paths to Florence involve some kind of ground travel. Amtrak's Palmetto and Silver Service trains stop in Florence, with connections to New York and Washington to the north and Orlando and Miami to the south. Greyhound and Southeastern Stages offer intercity bus service to Florence that connects the city to other destinations throughout the South.

Tampa

TPA-0TPA-1TPA-2

Sitting at the heart of the Gulf Coast, Tampa offers a perfect blend of cultural attractions and relaxing indulgences. Infused with a colourful mix of Cuban and Spanish cultural elements, the city of Tampa houses some of the most impressive historic buildings in the state, including the Henry B. Plant Museum, which boasts a permanent exhibition of Victorian-era artifacts. Animal lovers can also rejoice, as the city’s many aquariums and zoos will certainly melt your heart. Head down to the Tampa Electric’s Manatee Viewing Center for some heart-melting cuteness. And for animal lovers with a penchant for streaming docu-series, the Big Cat Rescue (yes, THAT one!) will be a great choice.

Most of the finest restaurants in town are concentrated around the Riverwalk area, which offers unrivaled views of the waterfront. Oystercatchers is reputed as one of the best establishments in town, so you should not miss out on it. Tampa’s cuisine features a very clear Cuban influence, and the best spot to try out these unique fusion dishes is at Ybor City.

The principal train station in the city is the Tampa Union Station, which is also a historic building. It is currently served by Amtrak. At the station, travellers can also take an Amtrak Thruway motorcoach to get to Orlando, Lakeland, Bradenton, etc. The main airport is Tampa International Airport, which is located just six miles west of downtown Tampa.

Station Information

Where does the bus leave from in Florence, SC?

Main departure station: 2301 W Lucas St (TA Gas Station)

Most buses depart from the main station in Florence, SC.

All bus stations in Florence, SC:

  • 2301 W Lucas St (TA Gas Station)

Where does the bus arrive in Tampa, FL?

Main arrival station: Tampa Bus Station

Located on Polk Street, the Greyhound Bus Terminal is Tampa’s main terminal for intercity bus service to cities such as Orlando, Miami, and Atlanta. Travellers on Greyhound will find ample parking in the surrounding area and a comfortable waiting room with washrooms and a small café inside. Conveniently located in the North Franklin St Historic District in downtown Tampa, the bus terminal is within a short walk of several dining options and connections to local public transit to travel within Tampa.

All bus stations in Tampa, FL:

  • Tampa Bus Station
  • Tampa 3801 USF

Need a return trip from Tampa, FL to Florence, SC?

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