Cheap train tickets from Portland, ME to Greenville, SC
Find and compare the best ground travel options in one place.
Trip Summary
There are usually 2 daily train trips available from Portland, ME to Greenville, SC. Travelling by train from Portland, ME to Greenville, SC usually takes 1 day, 16 hours and 49 minutes, but the fastest Amtrak train can make the trip in 1 day, 1 hour and 9 minutes.
- Distance
- 888 mi (1430 km)
- Fastest train
- 25h 9m
- Lowest price
- $549.06
- Trains per day
- 2
- Most frequent service
- Amtrak
- Train lines
- 1
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Portland, ME to Greenville, SC Train Schedule
Is it better to travel by bus or train from Portland, ME to Greenville, SC?
There is usually 1 daily bus trip available from Portland, ME to Greenville, SC.
Train | Bus | |
|---|---|---|
Avg. Price | Avg. Price$789.82 | Avg. Price$180.87Cheaper |
Daily Trips | Daily Trips2 | Daily Trips1 |
Duration | Duration40h 49m | Duration34h 51mFaster |

There are several train options that can take you from Portland, ME to Greenville, SC:
See more detailsWhat is the price of a train ticket from Portland, ME to Greenville, SC?
In the last month, train tickets from Portland, ME to Greenville, SC cost about $757 when booked at the cheapest time. Considering the distance between Portland, ME and Greenville, SC, tickets on this route are relatively expensive. Good news! You can find the cheapest tickets if you book your trip at least 1 day prior to the travel date. You’ll likely pay around $97.80 more if you wait to book until the last minute.
Average train ticket prices from Portland, ME to Greenville, SC by travel date
Over the next 30 days, a one-way train trip from Portland, ME to Greenville, SC will cost between $275 and $855. Book in advance to secure the best price in the next few weeks.
Average train ticket prices from Portland, ME to Greenville, SC by month
Ticket prices for the train from Portland, ME to Greenville, SC often fluctuate based on the time of year. For the best prices on this route, book in March when the average ticket price is only $327. If you're thinking of travelling from Portland, ME to Greenville, SC during June, keep in mind that train ticket prices may be higher than usual, with an average price of $550 during this time of year. The best way to score a cheap deal, even in June, is to book your trip well in advance.
Prices as travel date approaches
By booking your train trip from Portland, ME to Greenville, SC on Wanderu at least 1 day ahead of time, you can save about $97.80 on your ticket. Waiting until the last minute means missing out on these savings!
Which train should you take from Portland, ME to Greenville, SC?
Amtrak is the one and only train line which connects Portland, ME to Greenville, SC. The schedule is relatively limited as the train only runs twice a day.
| Train | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Amtrak | 2 | 40h 49m | $789.83 |
Frequently asked questions about travelling by train from Portland, ME to Greenville, SC
While the train is the main method of transportation from Portland, ME to Greenville, SC, it will only take you part of the way there. Please note that part of your trip will be on a different vehicle, most commonly a bus or express shuttle.
Trains leave the station in Portland, ME twice a day, so there are a couple of options depending on your preferred travel time. However, there are no direct trains. This means that you will need to disembark from your original train and board a connecting train at some point during your journey. You will need to remember to bring your carry-on luggage with you when you change trains. Depending on the carrier's policy, you may also be responsible for transferring your own checked baggage. If you're not set on travelling by train, you could always take the bus from Portland, ME to Greenville, SC for $180.
Trains per day
2
Direct trains
0
The distance between Portland, ME and Greenville, SC is approximately 1,430 kilometres. The average train journey between these two cities takes 1 day, 16 hours and 49 minutes, although the absolute fastest you could get there is 1 day, 1 hour and 9 minutes. Looking for ways to pass the time? Most trains are equipped with Wi-Fi, which means you can stream music, browse social media or get some work done during your ride. That said, in case your train has a spotty signal, or is among the few without Wi-Fi, we also recommend downloading TV shows and movies to your mobile device in advance of your trip. That way the ride will fly by whatever the Wi-Fi situation.
Distance (mi)
888
Distance (km)
1430
The earliest train departs Portland, ME at 4:15 a.m. while the last train of the day leaves at 6:00 p.m. To see all scheduled departure times, use the search function on this page to get the full schedule for your specific travel dates.
First train
4:15am
Last train
6:00pm
Trains from Portland, ME to Greenville, SC are the most crowded on Wednesday. Tickets also tend to be more expensive then. If you are looking for a great deal on your train tickets or just want extra room to stretch out, consider travelling on Wednesday instead, as it tends to be the least crowded day of the week.
Busiest
Wednesday
Least crowded
Wednesday
City Information
Portland



Portland is Maine's largest city and, because of that, the main transportation hub in the state. From Portland, travellers can easily reach destinations such as Boston, Albany, and even Gainesville, Texas, by a combination of buses, trains, and ferries. And there’s plenty to do in the city, even if you’re travelling solo.
Since its foundation in 1786, Portland has recovered from no less than four major fires, creating a fascinating blend of old and new. The dedicated Arts District around upper Congress Street has a smattering of important museum collections, including the Portland Museum of Art, the state's oldest public art institution.
The West End hosts the majority of Portland's historic buildings, creating an olde worlde feel. However, the presence of several well-regarded schools and colleges ensures Portland remains one of the most vibrant small cities in the U.S.
After several years of hardship, the Old Port district has once again become the centre of the action. Its attractive cobblestone streets and 19th-century red-brick warehouses now contain a selection of on-trend cafes, bars, and boutique stores. At the same time, it's still possible to watch the time-honored tradition of fishermen unloading their lobster pots onto the foreshore.
East of the downtown area, you'll find Munjoy Hill. It's a district with strong Irish and Italian roots, making it one of the best places in Portland to enjoy the authentic cuisine of Italy. It’s no wonder we named Portland one of our top vacation destinations in Maine.
Greenville



As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
Station Information
Where is the train station in Portland, ME?
Main departure station: 100 Thompsons Pt Rd

The Portland Transportation Center is located at 100 Thompsons Pt Rd, about two miles from Portland's Old Port area. Concord Coach Lines buses and Amtrak's Downeaster trains en route to Boston or Brunswick stop at this station. Inside the station, you'll find plenty of seating, washrooms, vending machines, and information desks for each travel company. In addition, there is plenty of paid parking in front of the station available to passengers.
All train stations in Portland, ME:
- 100 Thompsons Pt Rd
Where is the train station in Greenville, SC?
Main arrival station: 1120 W Washington St
Greenville, SC has one train station.
All train stations in Greenville, SC:
- 1120 W Washington St

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