Cheap bus tickets from Greenville, SC to New Orleans, LA
Find and compare the best ground travel options in one place.
Bus from Greenville, SC to New Orleans, LA: Journey Information
There are 2 intercity buses per day from Greenville, SC to New Orleans, LA. Travelling by bus from Greenville, SC to New Orleans, LA usually takes around 15 hours and 4 minutes, but the fastest Greyhound bus can make the trip in 13 hours and 15 minutes.
- Distance
- 561 mi (903 km)
- Shortest duration
- 13h 15m
- Cheapest price
- $151.34
- Trips per day
- 2
- Most frequent service
- Greyhound
- Bus lines
- 1
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Greenville, SC to New Orleans, LA Bus Schedule

There are several bus options that can take you from Greenville, SC to New Orleans, LA:
See more detailsHow much is a bus ticket from Greenville, SC to New Orleans, LA?
Bus tickets for a trip from Greenville, SC to New Orleans, LA cost about $187 when you book at the cheapest time, 1 day ahead. Bus tickets on this route can be a bit expensive due to the length of the trip. But even with a higher price tag, taking the bus is often more affordable than flying to New Orleans, LA. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Greenville, SC to New Orleans, LA by travel date
If you're planning to travel by bus from Greenville, SC to New Orleans, LA in the next month, the average ticket price is expected to range from $112 to $128. The cheapest bus tickets available in the next few weeks are for trips departing on November 17, 2026. If you’re looking to travel to New Orleans, LA this week, bus tickets are available starting at $113.
Average bus ticket prices from Greenville, SC to New Orleans, LA by month
Taking the bus from Greenville, SC to New Orleans, LA is usually cheapest in October, when the average ticket price is only $130. If you're planning to take the bus from Greenville, SC to New Orleans, LA during February, keep in mind that bus ticket prices may be higher than usual, with an average price of $213. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To save money on bus tickets and ensure availability, it's always best to book in advance.
What bus companies travel from Greenville, SC to New Orleans, LA?
There is one intercity bus company available to search and book on Wanderu that operates from Greenville, SC to New Orleans, LA. Greyhound is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 2 | 15h 4m | $195.29 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Greenville, SC to New Orleans, LA every day, with the average journey taking around 15 hours and 4 minutes to complete. Bus tickets for Greyhound trips to New Orleans, LA usually start from $151.34.






Frequently asked questions about travelling by bus from Greenville, SC to New Orleans, LA
There are usually only 2 buses per day from Greenville, SC to New Orleans, LA. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip. Need more travel options? Consider taking the train from Greenville, SC to New Orleans, LA; ticket prices start at $230.
Trips per day
2
Direct trips
0
The bus takes an average of 15 hours and 4 minutes to cover the 903 kilometres from Greenville, SC to New Orleans, LA. However, the fastest bus only takes 13 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
561
Distance (km)
903
The first bus leaves at 2:50 p.m. and the last bus leaves at 8:20 p.m. To see the times for all buses from Greenville, SC to New Orleans, LA, enter your specific travel dates in the search bar.
Earliest bus
2:50pm
Latest bus
8:20pm
Tuesday is usually the day of the week when buses are busiest. If you are planning to travel on a Tuesday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, travelling mid-week is your best bet.
Most crowded
Tuesday
Least crowded
Wednesday
City Information
Greenville



As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
New Orleans



New Orleans is the most populous city in the southern state of Louisiana and one of the most popular party destinations in the whole world. Known as The Big Easy, New Orleans is famous for its distinct French-Spanish architecture, Creole cuisine, and unique music. Around the globe, New Orleans is best known as the host city of Mardi Gras, a late-winter carnival known for flashy costumes and never-ending street parties. Because of that, NOLA is consistently among the preferred vacation destinations among spring breakers and post-grad travellers.
There’s a lot more to New Orleans than just partying, though. While you’re in town, connect with the artistic side of your personality with a visit to the famed New Orleans Museum of Art where you will find the South’s most impressive collection of French and American art. A visit to the Big Easy will not be complete without stopping by some of the city’s iconic cemeteries. Whether you take a guided tour or you explore on your own, you will learn a lot about the area’s history and urban legends.
New Orleans is one of the main economic and commercial centres of the U.S. Gulf Coast region, and as such it is easily accessible by all kinds of transportation. The airport is located not too far from the city centre, while the city’s main bus and train station, the Union Passenger Terminal, is placed right in the heart of downtown New Orleans.
Station Information
Where does the bus leave from in Greenville, SC?
Main departure station: 1116 Woodruff Rd
Most buses depart from the main station in Greenville, SC.
All bus stations in Greenville, SC:
- 1116 Woodruff Rd
Where does the bus arrive in New Orleans, LA?
Main arrival station: Union Term - 1001 Loyola Ave

Opened in 1954 to replace the five depots spread throughout the city, the Union Passenger Terminal connects all of New Orleans’ passenger rail into one iconic building. To this day, it remains the largest transportation hub in New Orleans and is a key link for travel throughout the Southern United States. Three of Amtrak’s long distance train lines end their service at Union Passenger Terminal: the City of New Orleans line from Chicago, the Crescent line from New York City, and the Sunset Limited line from Los Angeles to New Orleans. Buses operated by Greyhound and Jefferson Lines also serve this station, as well as public transit which connects to New Orleans’ famous streetcars. At the station, there are shops, a game room, and food for purchase, and the city’s must-visit French Quarter is just a mile away.
All bus stations in New Orleans, LA:
- Union Term - 1001 Loyola Ave
Need a return trip from New Orleans, LA to Greenville, SC?
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