Cheap bus tickets from New Orleans, LA to Greenville, SC
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Bus from New Orleans, LA to Greenville, SC: Journey Information
There is one daily bus from New Orleans, LA to Greenville, SC. Travelling by bus from New Orleans, LA to Greenville, SC usually takes around 16 hours and 50 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
- Distance
- 561 mi (903 km)
- Shortest duration
- 16h 50m
- Cheapest price
- $241.32
- Trips per day
- 1
- Most frequent service
- Greyhound
- Bus lines
- 1
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New Orleans, LA to Greenville, SC Bus Schedule
Is it better to travel by bus or train from New Orleans, LA to Greenville, SC?
There is usually 1 daily train trip available from New Orleans, LA to Greenville, SC.
Bus | Train | |
|---|---|---|
Avg. Price | Avg. Price$241.32Cheaper | Avg. Price$243.12 |
Daily Trips | Daily Trips1 | Daily Trips1 |
Duration | Duration16h 50m | Duration16h 8mFaster |

There are several bus options that can take you from New Orleans, LA to Greenville, SC:
See more detailsPrice trends for buses from New Orleans, LA to Greenville, SC
Average bus ticket prices from New Orleans, LA to Greenville, SC by travel date
Average bus ticket prices from New Orleans, LA to Greenville, SC by month
Prices as travel date approaches
What bus companies travel from New Orleans, LA to Greenville, SC?
There is one intercity bus company available to search and book on Wanderu that operates from New Orleans, LA to Greenville, SC. Greyhound is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 1 | 16h 50m | $241.32 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trip from New Orleans, LA to Greenville, SC every day, with the average journey taking around 16 hours and 50 minutes to complete. Bus tickets for Greyhound trips to Greenville, SC usually start from $241.32.






Frequently asked questions about travelling by bus from New Orleans, LA to Greenville, SC
There is usually only one bus per day from New Orleans, LA to Greenville, SC. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip. Need more travel options? Consider taking the train from New Orleans, LA to Greenville, SC; ticket prices start at $230.
Trips per day
1
Direct trips
0
The bus takes an average of 16 hours and 50 minutes to cover the 903 kilometres from New Orleans, LA to Greenville, SC. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
561
Distance (km)
903
There is usually only one bus per day from New Orleans, LA to Greenville, SC. It leaves the station in New Orleans, LA at 8:50 p.m. each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
Earliest bus
8:50pm
Latest bus
8:50pm
The busiest and least busy days to travel on this route tend to change frequently from week to week. Weather, holidays, local events, and other factors can affect how crowded the bus is on any given day.
Most crowded
Tuesday
Least crowded
Tuesday
City Information
New Orleans



New Orleans is the most populous city in the southern state of Louisiana and one of the most popular party destinations in the whole world. Known as The Big Easy, New Orleans is famous for its distinct French-Spanish architecture, Creole cuisine, and unique music. Around the globe, New Orleans is best known as the host city of Mardi Gras, a late-winter carnival known for flashy costumes and never-ending street parties. Because of that, NOLA is consistently among the preferred vacation destinations among spring breakers and post-grad travellers.
There’s a lot more to New Orleans than just partying, though. While you’re in town, connect with the artistic side of your personality with a visit to the famed New Orleans Museum of Art where you will find the South’s most impressive collection of French and American art. A visit to the Big Easy will not be complete without stopping by some of the city’s iconic cemeteries. Whether you take a guided tour or you explore on your own, you will learn a lot about the area’s history and urban legends.
New Orleans is one of the main economic and commercial centres of the U.S. Gulf Coast region, and as such it is easily accessible by all kinds of transportation. The airport is located not too far from the city centre, while the city’s main bus and train station, the Union Passenger Terminal, is placed right in the heart of downtown New Orleans.
Greenville



As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
Station Information
Where does the bus leave from in New Orleans, LA?
Main departure station: Union Term - 1001 Loyola Ave

Opened in 1954 to replace the five depots spread throughout the city, the Union Passenger Terminal connects all of New Orleans’ passenger rail into one iconic building. To this day, it remains the largest transportation hub in New Orleans and is a key link for travel throughout the Southern United States. Three of Amtrak’s long distance train lines end their service at Union Passenger Terminal: the City of New Orleans line from Chicago, the Crescent line from New York City, and the Sunset Limited line from Los Angeles to New Orleans. Buses operated by Greyhound and Jefferson Lines also serve this station, as well as public transit which connects to New Orleans’ famous streetcars. At the station, there are shops, a game room, and food for purchase, and the city’s must-visit French Quarter is just a mile away.
All bus stations in New Orleans, LA:
- Union Term - 1001 Loyola Ave
Where does the bus arrive in Greenville, SC?
Main arrival station: 1116 Woodruff Rd
All buses from New Orleans, LA arrive at one main station in Greenville, SC.
All bus stations in Greenville, SC:
- 1116 Woodruff Rd
Need a return trip from Greenville, SC to New Orleans, LA?
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