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Journey Information
There are 2 intercity buses per day from Santa Ana to Mesa. Traveling by bus from Santa Ana to Mesa usually takes around 10 hours and 10 minutes, but the fastest Greyhound bus can make the trip in 10 hours,
| Distance | 348 mi (560 km) |
| Shortest duration | 10h 0m |
| Cheapest price | €76.31 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
What bus companies travel from Santa Ana to Mesa?
There is one intercity bus company available to search and book on Wanderu that operates from Santa Ana to Mesa. Greyhound is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 2 | 10h 10m | €80.96 |
Greyhound is the largest nationwide coach carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Santa Ana to Mesa every day, with the average journey taking around 10 hours and 10 minutes to complete. Bus tickets for Greyhound trips to Mesa usually start from €76.
Frequently Asked Questions
The bus takes an average of 10 hours and 10 minutes to cover the 560 kilometers from Santa Ana to Mesa. However, the fastest bus only takes 10 hours. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 16:00 and the last bus leaves at 21:00. To see the times for all buses from Santa Ana to Mesa, enter your specific travel dates in the search bar.
City Information
Santa Ana
Image credit: Unsplash
Santa Ana is a sunny city in Orange County located between Anaheim and Irvine in the greater Los Angeles area. Downtown Santa Ana bustles with independent breweries, diverse restaurants, unique retail shops, weekly pop-up markets, and art centers. This lively downtown area, in addition to Santa Ana's live-work housing and creative working spaces, make it attractive to young professionals.
One of the most popular spots for visitors is the Santa Ana Zoo, where little ones can enjoy a carousel and mini-train ride along with the animal exhibits. Architecture enthusiasts will love seeing the Bowers Museum, built in a Mission Revival style, and the Heritage Museum, which has restored homes from the 1890s.
The Orange County Transportation Authority and several shuttle services provide transit within Santa Ana. Santa Ana is easily accessible from over 20 other cities by Amtrak Thruway bus or on the Amtrak Pacific Surfliner train. The primary airport for Orange County, John Wayne Airport, is located in Santa Ana and also makes it easy to travel to this vibrant SoCal spot.
Station Information
Where does the bus leave from in Santa Ana?
Main departure station: Reg Transp Ctr - 1000 E Santa Ana Blvd
Most buses depart from the main station in Santa Ana.
All bus stations in Santa Ana:
Reg Transp Ctr - 1000 E Santa Ana Blvd
Where does the bus arrive in Mesa?
Main arrival station: Bus Station
All buses from Santa Ana arrive at one main station in Mesa.
Bus stations in Mesa:
Bus Station
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Need a return trip from Mesa to Santa Ana?
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