|Shortest Duration||20h 5m|
|Trips per day||1|
FlixBus operates, on average, 1 bus schedule(s) from Mainz to Rome. The average FlixBus ticket to Rome costs $63.18. In Mainz, FlixBus departs from Central Station and no other station. In Rome, FlixBus arrives at Largo Guido Mazzoni and no other station.
An average trip on FlixBus from Mainz to Rome takes 21 hours and 15 minutes, while the fastest available FlixBus trip will get you to Rome in 20 hours and 5 minutes,