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San Francisco to Key West bus

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San Francisco - Key West Bus Schedule

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Journey Information

There are 3 intercity buses per day from San Francisco to Key West. Traveling by bus from San Francisco to Key West usually takes around 85 hours and 35 minutes, but the fastest FlixBus US bus can make the trip in 81 hours and 20 minutes.

Distance2547 mi (4099 km)
Shortest duration81h 20m
Cheapest price$236.45
Most frequent serviceFlixBus US
Bus lines1

What bus companies travel from San Francisco to Key West?

There is one intercity bus company available to search and book on Wanderu that operates from San Francisco to Key West. FlixBus US connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US33d 13h 36m$349.49
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from San Francisco to Key West, and the average ticket for this route costs only .

Frequently Asked Questions

The bus takes an average of 85 hours and 35 minutes to cover the 2547 miles from San Francisco to Key West. However, the fastest bus only takes 81 hours and 20 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Sunday tends to be the busiest day for buses, as many passengers take the bus to Key West at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.

The first bus leaves at 8:00am and the last bus leaves at 11:00pm. To see the times for all buses from San Francisco to Key West, enter your specific travel dates in the search bar.

There are 3 scheduled buses that travel from San Francisco to Key West every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.

City Information

San Francisco

San Francisco, CA - SFO-0

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San Francisco, CA - SFO-1

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San Francisco, CA - SFO-2

Image credit: Unsplash

Located in the heart of Northern California's Bay Area, San Francisco is a geographically small but culturally huge city known for its historic cable cars, active waterfront, and the eclectic mix of hippies and techies who call it home. While it might be one of the most expensive U.S. cities to live in, San Fran can actually be very cheap to visit, and there is no shortage of unique sights to see.

If the city's omnipresent fog (nicknamed "Karl the Fog" by locals) takes a break, the best views and Instagram photo ops of the world-famous Golden Gate Bridge are found in Golden Gate Park. Stroll through the oldest Chinatown in North America to find the perfect dim sum, or if you and your boo prefer a little Full House moment, try a romantic picnic at Alamo Square Park in front of the Victorian "Painted Ladies." After all, San Francisco is one of the best vacation destinations for couples.

Since the city is condensed onto a small peninsula, exploring by bike is an efficient and scenic way to get around. When you’re ready to travel beyond city limits, San Francisco is a convenient hub for trips throughout Northern California. It's actually the first stop on Wanderu's West Coast Wine Tour, with the next stop, obviously, in Napa Valley. Whether traveling by bus, train, or through either of the two nearby airports, San Francisco is a can't-miss destination.

Key West

Key West, FL - KWT-0

Image credit: Unsplash

Key West, FL - KWT-1

Image credit: Unsplash

Key West, FL - KWT-2

Image credit: Unsplash

Key West is the southernmost city in the contiguous U.S. and a popular tourist destination in Florida. Known for its abundance of sea wildlife, Key West is a fantastic place for you to book a boat tour and enjoy the Gulf of Mexico's coral reefs. Tours also offer unique opportunities like dolphin watching, snorkeling, and much more. For the best beach around, head toward the Fort Zachary Taylor Historic State Park, where you can sunbathe and fish with ease. The Key West Butterfly & Nature Conservatory is a magical spot to learn more about different butterfly variations.

Seafood is still the staple of Key West's cuisine, but the distinct Caribbean and Cuban touch will set the city's food scene apart from others. For the best authentic Cuban specialties, try El Siboney. If you enjoy classic Floridan dishes, Blue Heaven will not disappoint you.

Although Key West is an island city on the Florida Keys archipelago, the Overseas Highway connects to the mainland. This means you can easily catch a bus directly to Key West. Domestic and international flights go through the centrally-located Key West International Airport.

Station Information

Where does the bus leave from in San Francisco?

Main departure station: Caltrain Station - 5th & Townsend St

Most buses depart from the main station in San Francisco.

All bus stations in San Francisco:

  • Caltrain Station - 5th & Townsend St

Where does the bus arrive in Key West?

Main arrival station: Ky West Bus Station

These are the two stations where buses may stop when they arrive in Key West.

All bus stations in Key West:

  • Ky West Bus Station

  • 908 Caroline St, between Grinnell and Margaret Sts

Get around town with Moovit

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Need a return trip from Key West to San Francisco?

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