Cheap bus tickets from Port Saint Lucie to Key West
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Port Saint Lucie to Key West Bus Schedule
Bus from Port Saint Lucie to Key West: Journey Information
There is one daily bus from Port Saint Lucie to Key West. Traveling by bus from Port Saint Lucie to Key West usually takes around 12 hours and 10 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 208 mi (334 km) |
| Shortest duration | 12h 10m |
| Cheapest price | $40.97 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Port Saint Lucie to Key West?
There is one intercity bus company available to search and book on Wanderu that operates from Port Saint Lucie to Key West. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 12h 10m | $60.55 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Port Saint Lucie to Key West, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Port Saint Lucie to Key West
The bus takes an average of 12 hours and 10 minutes to cover the 208 miles from Port Saint Lucie to Key West. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Friday is the busiest travel day for buses as people head from Port Saint Lucie to Key West for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
There is usually only one bus per day from Port Saint Lucie to Key West. It leaves the station in Port Saint Lucie at 3:00am each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Port Saint Lucie

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Map out a Florida vacation and it will most probably lead you to Port Saint Lucie. Situated on the Atlantic Ocean coastline of southern Florida, the city includes long ribbons of pristine sand beaches that are an ideal escape from it all.
Head inland, and you'll find a heart ringed by stunning waterways and roughly 20,000 acres of a nature reserve that are just waiting to be discovered. There are various opportunities to try your luck on a fishing adventure, strike out with a rucksack on a day's hike, or ride horses at full gallop in the shallows. Should you prefer, there's also ample opportunity to take to the saddle of a mountain bike to raise the heart rate or enjoy a sedate round of golf at PGA-level facilities.
Neatly positioned between Miami to the south and Orlando to the north, Port Saint Lucie makes for a great way to break up a journey. Buses make frequent arrivals at Port Saint Lucie Service Plaza at Florida Turnpike Mile 144, just two miles from the city center, as well as at 2031 SW Gatlin Blvd and La Bonita.
The ride to Orlando or Miami will take around 3.5 hours, while if you choose, it's possible to head as far afield as Philadelphia, too.
Key West

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Key West is the southernmost city in the contiguous U.S. and a popular tourist destination in Florida. Known for its abundance of sea wildlife, Key West is a fantastic place for you to book a boat tour and enjoy the Gulf of Mexico's coral reefs. Tours also offer unique opportunities like dolphin watching, snorkeling, and much more. For the best beach around, head toward the Fort Zachary Taylor Historic State Park, where you can sunbathe and fish with ease. The Key West Butterfly & Nature Conservatory is a magical spot to learn more about different butterfly variations.
Seafood is still the staple of Key West's cuisine, but the distinct Caribbean and Cuban touch will set the city's food scene apart from others. For the best authentic Cuban specialties, try El Siboney. If you enjoy classic Floridan dishes, Blue Heaven will not disappoint you.
Although Key West is an island city on the Florida Keys archipelago, the Overseas Highway connects to the mainland. This means you can easily catch a bus directly to Key West. Domestic and international flights go through the centrally-located Key West International Airport.
Station Information
Where does the bus leave from in Port Saint Lucie?
Main departure station: Prt St Lucie (Park & Ride)
Most buses depart from the main station in Port Saint Lucie.
All bus stations in Port Saint Lucie:
Prt St Lucie (Park & Ride)
Where does the bus arrive in Key West?
Main arrival station: Ky West Bus Station
All buses from Port Saint Lucie arrive at one main station in Key West.
All bus stations in Key West:
Ky West Bus Station
Get around town with Moovit
Need a return trip from Key West to Port Saint Lucie?
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