Cheap bus tickets from Myrtle Beach to Lake City
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Myrtle Beach to Lake City Bus Schedule
Bus from Myrtle Beach to Lake City: Journey Information
There is one daily bus from Myrtle Beach to Lake City. Traveling by bus from Myrtle Beach to Lake City usually takes around 21 hours and 35 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 327 mi (526 km) |
| Shortest duration | 21h 35m |
| Cheapest price | $189.56 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Myrtle Beach to Lake City?
There is one intercity bus company available to search and book on Wanderu that operates from Myrtle Beach to Lake City. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 21h 35m | $189.56 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Myrtle Beach to Lake City, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Myrtle Beach to Lake City
The bus takes an average of 21 hours and 35 minutes to cover the 327 miles from Myrtle Beach to Lake City. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from Myrtle Beach to Lake City. It leaves the station in Myrtle Beach at 11:00am each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Station Information
Where does the bus leave from in Myrtle Beach?
Main departure station: J&D Travel - 511 7th Ave N
Most buses depart from the main station in Myrtle Beach.
All bus stations in Myrtle Beach:
J&D Travel - 511 7th Ave N
Where does the bus arrive in Lake City?
Main arrival station: 251 S Marion Ave
All buses from Myrtle Beach arrive at one main station in Lake City.
All bus stations in Lake City:
251 S Marion Ave
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