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Find bus tickets from St Louis to Chicago

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Journey Information

St Louis to Chicago bus - cost & duration

Cheapest price$34.24
Fastest time6h 15m
Trips per day13
Bus lines2

St Louis to Chicago Route Map

St Louis Chicago

Frequently Asked Questions

Is it safe to travel by bus from St Louis to Chicago during the COVID-19 pandemic?

Our bus partners have implemented several different policies to keep you safe during the COVID-19 pandemic. From limiting vehicle capacity to enhancing cleaning protocols and upgrading air filters, bus carriers are committed to maintaining a safe environment. For details on what each company is doing to ensure their fleet remains safe for travel, click here.

In addition, federal law requires all bus passengers to wear a face covering for the entire duration of the trip. Please make sure you are wearing a face mask or you may not be allowed to board the bus.

Please visit our COVID-19 Travel Guide for more information on all carrier policies and the latest travel advisories issued by every U.S. state, Canadian province, and European country.

How much is a bus ticket from St Louis to Chicago?

Based on daily average prices in last 30 days, $38.15 was the low point for bus fares from St Louis to Chicago. Buses from Chicago to St Louis are similarly priced. Any tickets cheaper than $38.15 could be considered a great deal.

The best way to find cheap deals on bus tickets is by booking as early as possible, since most bus companies increase the price as the travel date approaches. You should book at least 11 days in advance. By doing so, you could save $29.55 on your ticket compared to booking at the last minute.

How long is the bus ride?

The bus usually takes around 10 hours and 1 minute to cover the 262 miles (422 kilometers) from St Louis, MO to Chicago, IL. However, the fastest bus only takes 6 hours and 15 minutes. The trip is definitely on the longer side, so plan to get comfortable on the bus. It's a good idea to bring water and snacks.

What is the busiest day of the week to travel by bus?

Friday is the busiest travel day for buses as people head from St Louis to Chicago for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Saturday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Saturday ticket is the way to go.

When do the earliest and latest buses leave St Louis?

The first bus leaves at 7:00am and the last bus leaves at 11:00pm. To see the times for all buses from St Louis to Chicago, enter your specific travel dates in the search bar.

How many buses are there each day?

There are 13 scheduled buses that travel from St Louis to Chicago every day, so you have a decent number of options to choose from. This includes 2 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.

Need more travel options? Consider taking the train from St Louis to Chicago; ticket prices start at $31.70.

What bus companies travel from St Louis to Chicago?

There are a couple of bus lines that have daily service from St Louis, Missouri to Chicago, Illinois. Of these two services, Greyhound usually offers more choice, with 12 bus trips per day.

BusDaily TripsAvg. TimeAvg. Price
Burlington Trailways113h 11m$102.40
Greyhound129h 33m$46.74

Book Burlington Trailways from St Louis to Chicago from $102. There are 1 Burlington Trailways schedules from St Louis to Chicago and you can expect on average to pay $102 for a Burlington Trailways ticket to Chicago. In St Louis, Burlington Trailways departs to Chicago from Lambert Intl Apt Busport and no other station. In Chicago, Burlington Trailways arrives at Bus Station - 630 W Harrison St and no other station. An average trip on Burlington Trailways from St Louis to Chicago takes 13 hours and 11 minutes, while the fastest available Burlington Trailways trip will get you to Chicago in 6 hours and 15 minutes, On weekends, Burlington Trailways offers 1 trip per day and you could expect to pay $102 for a weekend getaway trip to Chicago.

Book Greyhound from St Louis to Chicago from $34. There are 12 Greyhound schedules from St Louis to Chicago and you can expect on average to pay $47 for a Greyhound ticket to Chicago. In St Louis, Greyhound departs to Chicago from Gateway Station - 430 S 15th St and 1 other station. In Chicago, Greyhound arrives at Dan Ryan Bus Station and 3 other stations. An average trip on Greyhound from St Louis to Chicago takes 9 hours and 33 minutes, while the fastest available Greyhound trip will get you to Chicago in 6 hours and 15 minutes, On weekends, Greyhound offers 12 trips per day and you could expect to pay $48 for a weekend getaway trip to Chicago.

Where does the bus leave from in St Louis?

St Louis, Missouri has two bus stations with service to Chicago, Illinois:

  • Gateway Station - 430 S 15th St
  • Lambert Intl Apt Busport

Where does the bus arrive in Chicago?

Buses arrive in Chicago at 4 stations, depending on which bus line you are traveling with. These are the main bus stations in Chicago, Illinois:

  • Bus Station - 630 W Harrison St
  • Dan Ryan Bus Station
  • Union Station - 225 S Canal St
  • 5800 N Cumberland Ave

Price trends for buses from St Louis to Chicago

Average prices by travel date

$76$51$25MarMar

Monthly average prices

$32$25$19$13$6AMJJASONDJFM

Prices as travel date approaches

$95$76$57$38$193020100

Bus Trip Reviews from Wanderu Customers

Overall score for buses from St Louis, MO to Chicago, IL

(Based on 11 ratings and reviews)

4.5

5.0

Ajdin

November 16, 2019 - Vacation

Megabus

Lower back hurts on the chairsLower back hurts on the chairs

5.0

Rimas

October 1, 2019 - Solo travel

Megabus

Pros: Other. Cons: Other. Tips: Good. Pros: Other. Cons: Other. Tips: Good.

4.0

Michelle

August 19, 2019 - Visiting family

Greyhound

Pros: Did what it said it would do. Glad for the stop break which was sufficient for a healthy break. Cons: Chair was in recline mode which is fine, but not able to adjust which made it a little uncomfortable. That is my only winge. Tips: Sit back and enjoy. Pros: Did what it said it would do. Glad for the stop break which was sufficient for a healthy break. Cons: Chair was in recline mode which is fine, but not able to adjust which made it a little uncomfortable. That is my only winge. Tips: Sit back and enjoy.

1.0

Carla

July 7, 2019 - Visiting friends

Megabus

Pros: No comment. Cons: Running on time,. Tips: It’s was the worse trip on the mega I used to enjoy riding the bus but that was my last kids was crying the hold way back to Chicago people rude talking very loud using bad language it was just to much Done ✅. Pros: No comment. Cons: Running on time,. Tips: It’s was the worse trip on the mega I used to enjoy riding the bus but that was my last kids was crying the hold way back to Chicago people rude talking very loud using bad language it was just to much Done ✅.

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