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Cheap bus tickets from Prague to Brussels

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Prague to Brussels Bus Schedule

Bus from Prague to Brussels: Journey Information

There are 16 intercity buses per day from Prague to Brussels. Traveling by bus from Prague to Brussels usually takes around 18 hours and 10 minutes, but the fastest RegioJet bus can make the trip in 12 hours,

Distance446 mi (719 km)
Shortest duration12h 0m
Cheapest price$47.52
Trips per day2
Most frequent serviceFlixBus
Bus lines2

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What bus companies travel from Prague to Brussels?

There are two bus lines that have daily service from Prague to Brussels that you can compare and book on Wanderu. Of these two carriers, FlixBus usually offers more choice, with 16 scheduled trips per day.

BusDaily TripsAvg. TimeAvg. Price
FlixBus1618h 11m$101.63
RegioJet212h 45m$56.00
  • First launched in Germany in 2013, FlixBus has become one of the largest intercity bus companies in Europe. Its fleet travels through nearly every country in Europe, including the U.K. FlixBus operates an average of 16 trips from Prague to Brussels, and usually makes the trip in about 18 hours and 11 minutes. On your trip, you'll enjoy Wi-Fi and live GPS, as well as restrooms, air conditioning, and power outlets.

  • Book RegioJet from Prague to Brussels from $53. There are 2 trips per day offered by RegioJet from Prague to Brussels and you can expect on average to pay for a RegioJet ticket to Brussels. In Prague, RegioJet departs to Brussels from Aviatická 1017/2 and one other station. In Brussels, RegioJet arrives at Gare du Midi .

    An average trip on RegioJet from Prague to Brussels takes 12 hours and 45 minutes , while the fastest available RegioJet trip will get you to Brussels in 12 hours and 0 minutes .

Frequently asked questions about traveling by bus from Prague to Brussels

The bus takes an average of 18 hours and 10 minutes to cover the 446 miles from Prague to Brussels. However, the fastest bus only takes 12 hours. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Sunday tends to be the busiest day for buses, as many passengers take the bus to Brussels at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.

The first bus leaves at 12:00am and the last bus leaves at 11:00pm. To see the times for all buses from Prague to Brussels, enter your specific travel dates in the search bar.

There are 16 scheduled buses that travel from Prague to Brussels every day, so you have a decent number of options to choose from. This includes 2 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.

City Information

Prague

With storied churches and beautiful castles, Prague was once the hidden gem of Europe, and it has now revealed its beauty to the world. Prague’s prized landmark is the majestic Prague Castle, which is the largest castle complex in the world. The castle is an amalgamation of many different architectural styles, making it a very special destination to visit. You might even get to see the president of Czechia as well, since it is his office! If you simply want to stroll around and enjoy the vibe of the city, head for the Old Town Square, which has seen very few changes since its conception in the 12th century. If you are not afraid of a little hiking, head to Petrin Hill, which is one of the largest green areas in the city. The area also houses the Rose Garden and Seminary Garden, featuring more than 2,100 trees.

Prague’s food scene is not as well-known as other famous cities’, but the local dishes such as knedlíky or bramboráky will pleasantly surprise you. La Degustation Boheme Bourgeoise is a Michelin-starred restaurant that offers amazing Czech dishes. For local beers, don’t hesitate to check out U Medvídku.

Praha hlavní nádraží is the largest international train station in Prague and it’s located right in the heart of the city. Not too far from the train station is Prague’s central bus station. The principal airport in the city is the Václav Havel Airport Prague.

Brussels

The center of European activities, Brussels is a cosmopolitan hub that features many cultural elements, making it one of the top destinations for international travelers. Sitting at the heart of Brussels is the famous Grand-Place, a world heritage site that boasts many nearby Gothic and Baroque architectural marvels. During the holiday season, the square hosts the Winter Wonders light show, as well as a giant Christmas tree. If you enjoy museums, don’t miss out on the Musical Instruments Museum, which is housed in an Art Nouveau building. Featuring as many as 1,200 instruments from around the world, the museum is every music fan’s dream. If you want to go on a shopping spree while in Brussels, head for the Les Galeries Royales Saint-Hubert, which is housed in a stunning Renaissance-style arcade.

Brussels is the home to many Michelin-starred restaurants, and its food scene is among the top-rated in the country. For those wishing to enjoy a contemporary twist on Belgian classics, head towards La Quincaillerie. If seafood is your go-to, Noordzee Mer du Nord will definitely satisfy your palate.

Brussels’ three main rail stations are Brussels-South, Brussels-Central, and Brussels-North, all of which are the busiest in the country. Gare du Midi, located in the Brussels-South station, is the main hub for bus travel in and out of Brussels. The city is served by several airports, the most prominent of which is the Brussels-National Airport, located 10 miles east of the city.

Station Information

Where does the bus leave from in Prague?

Prague Florenc Central Bus Station  - CZPRGDEFLX-0

Image credit: Elekes Andor

Link to image attribution

Main departure station: Prague Florenc Bus Station

Prague Florenc Central Bus Station is the city's largest and busiest bus station. The station complex is fully equipped with all the modern amenities you could ask for, including information services, luggage storage, public toilets, restaurants, and shops. Bus lines including FlixBus and RegioJet stop at the station, and Prague's central train station is less than 2km away for connections to rail travel. Right outside the bus station, you'll find the Florenc Metro stop, a hotel, several restaurants, and excellent shopping.

All bus stations in Prague:

  • Prague Florenc Bus Station

  • Aviatická 1017/2

  • Prague Anděl Ostrovského 34/1

  • Zličín

  • Main Railway Station

  • Hradčanská

  • Central Bus Station

  • Tomíčkova

  • kancelář u nástupiště č. 6

Where does the bus arrive in Brussels?

Main arrival station: Gare du Midi

Also known as Brussels-South railway station, the Gare du Midi is the primary train station serving Brussels. The station is technically located in Saint-Gilles, a city south of Brussels, but the Gare du Midi metro stop connects travelers to all of Brussels' sights and attractions. Many high-speed train services, including international train lines, run through the Gare du Midi. Brussels is connected to the famous Eurostar line through this station, along with Thalys and Deutsche Bahn lines. The large indoor station includes many retail shops, restaurants, and services like information desks and restrooms.

All bus stations in Brussels:

  • Gare du Midi

  • Magnolialaan 1

  • Avenue Fonsny

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