Cheap bus tickets from Mexicali to San Diego
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Bus from Mexicali to San Diego: Journey Information
There are 10 intercity buses per day from Mexicali to San Diego. Traveling by bus from Mexicali to San Diego usually takes around 7 hours and 43 minutes, but the fastest Greyhound bus can make the trip in 6 hours and 30 minutes.
Distance | 100 mi (160 km) |
Shortest duration | 6h 30m |
Cheapest price | $27.46 |
Most frequent service | Greyhound |
Bus lines | 2 |

What bus companies travel from Mexicali to San Diego?
There are two bus lines that have daily service from Mexicali to San Diego that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 5 scheduled trips per day.
Bus | Daily Trips | Avg. Time | Avg. Price |
---|---|---|---|
FlixBus US | 5 | 7h 43m | $30.36 |
Greyhound | 5 | 7h 43m | $30.36 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 5 trips per day from Mexicali to San Diego, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 5 bus trips from Mexicali to San Diego every day, with the average journey taking around 7 hours and 43 minutes to complete. Bus tickets for Greyhound trips to San Diego usually start from $27.
Frequently asked questions about traveling by bus from Mexicali to San Diego
The bus takes an average of 7 hours and 43 minutes to cover the 100 miles from Mexicali to San Diego. However, the fastest bus only takes 6 hours and 30 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 9:00am and the last bus leaves at 11:00am. To see the times for all buses from Mexicali to San Diego, enter your specific travel dates in the search bar.
City Information
San Diego



San Diego is known as "America's Finest City" for its sunny weather, white-sand beaches, and dazzling attractions from Belmont Park to SeaWorld. San Diego's 70 miles of pristine beaches include such gems as Mission Beach, Pacific Beach, La Jolla Cove, and Coronado Beach. The city's strong surfing culture may even inspire you to rent a surfboard and catch the epic waves, bro.
Visitors can spend days getting lost in Balboa Park, a 1,200-acre cultural hub which features 16 museums, immaculate gardens, and the world-famous San Diego Zoo. The historic heart of the city, Old Town, showcases San Diego's heritage and ties to Mexican culture, while other sights like the USS Midway pay tribute to the city's military and maritime history. Leave time for some evening exploring, too! San Diego is rated the #1 best city for craft beer in America, so don't miss out on the bars in the Gaslamp Quarter: 16 walkable blocks packed with nightlife and young crowds.
Two airports, as well as many bus and train options, mean it is easy to get to San Diego from afar or from nearby cities like Tijuana, Los Angeles, Phoenix, and Las Vegas.
Station Information
Where does the bus leave from in Mexicali?
Main departure station: Calzada Independecia
Most buses depart from the main station in Mexicali.
All bus stations in Mexicali:
Calzada Independecia
Where does the bus arrive in San Diego?
Main arrival station: San Ysidro Transit Center
Buses arrive in San Diego at 4 stations, depending on which bus line you are traveling with.
All bus stations in San Diego:
San Ysidro Transit Center
La Jolla - UC San Diego
San Diego Greyhound Bus Stop
2728 Congress St (Old Town SD)
Get around town with Moovit
Need a return trip from San Diego to Mexicali?
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