|Shortest Duration||13h 15m|
|Trips per day||1|
Book Greyhound from Gainesville to Knoxville from $90.00. Typically there is one Greyhound schedule per day from Gainesville to Knoxville and you can expect on average to pay $127.00 for a Greyhound ticket to Knoxville. In Gainesville, Greyhound departs to Knoxville from Bus Terminal - 101 NE 23rd Ave, In Knoxville, Greyhound arrives at Bus Terminal - 100 E Magnolia Ave,
An average trip on Greyhound from Gainesville to Knoxville takes 16 hours and 18 minutes, while the fastest available Greyhound trip will get you to Knoxville in 13 hours and 15 minutes,
On weekends, Greyhound offers 2 trips per day. A one way ticket costs $158.50 for a weekend trip to Knoxville.