Cheap bus tickets from Ames to Milwaukee
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Ames to Milwaukee Bus Schedule
Bus from Ames to Milwaukee: Journey Information
There are 2 intercity buses per day from Ames to Milwaukee. Traveling by bus from Ames to Milwaukee usually takes around 15 hours and 58 minutes, but the fastest Jefferson Lines bus can make the trip in 13 hours and 30 minutes.
| Distance | 300 mi (482 km) |
| Shortest duration | 13h 30m |
| Cheapest price | $168.00 |
| Most frequent service | Jefferson Lines |
| Bus lines | 1 |

What bus companies travel from Ames to Milwaukee?
There is one intercity bus company available to search and book on Wanderu that operates from Ames to Milwaukee. Jefferson Lines is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Jefferson Lines | 2 | 15h 58m | $172.02 |
Book Jefferson Lines from Ames to Milwaukee from $168. There are 2 trips per day offered by Jefferson Lines from Ames to Milwaukee and you can expect on average to pay for a Jefferson Lines ticket to Milwaukee. In Ames, Jefferson Lines departs to Milwaukee from Intermodal Station - 129 Hayward Ave . In Milwaukee, Jefferson Lines arrives at Intermodal Station - 433 W ST Paul Ave .
An average trip on Jefferson Lines from Ames to Milwaukee takes 15 hours and 58 minutes , while the fastest available Jefferson Lines trip will get you to Milwaukee in 13 hours and 30 minutes .
On weekends, Jefferson Lines offers 1 trip per day and you could expect to pay for a one way ticket for your weekend getaway trip to Milwaukee.
Frequently asked questions about traveling by bus from Ames to Milwaukee
The bus takes an average of 15 hours and 58 minutes to cover the 300 miles from Ames to Milwaukee. However, the fastest bus only takes 13 hours and 30 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
The first bus leaves at 12:00am and the last bus leaves at 12:00am. To see the times for all buses from Ames to Milwaukee, enter your specific travel dates in the search bar.
City Information
Milwaukee



Nestling on the banks of the great Lake Michigan, Milwaukee has some of the most scenic views around, making it every photographer’s perfect destination. Boasting 85 miles of scenic waterfront bike lanes, Milwaukee is the perfect spot to ride a bike and enjoy the sunset together with your friends. It is also the home of the Harley Davidson Museum, a vast waterfront gallery that offers 11 permanent exhibitions. The museum features not only bikes but also special items such as a whole engine room, making it a must-visit spot for bike enthusiasts. If you are not interested in bikes, the Basilica of St. Josaphat, which is modeled after St. Peter’s Basilica in the Vatican, offers many wondrous shots.
Milwaukee’s famous German bratwursts are a must-try for all visitors, and the best place to enjoy this dish is Usinger’s. Other similar establishments include Mader’s and Milwaukee Public Market. For authentic American eats, Leon's Frozen Custard Drive-In offers amazing sloppy-joe burgers.
The Milwaukee Intermodal Station is the city’s main transportation hub. Visitors can catch both buses and trains at this location. The city is served by two airports. The Milwaukee Mitchell International Airport on the southern edge of the city handles commercial flights, while the Lawrence J. Timmerman Airport in the northwest handles private flights.
Station Information
Where does the bus leave from in Ames?
Main departure station: Intermodal Station - 129 Hayward Ave
Most buses depart from the main station in Ames.
All bus stations in Ames:
Intermodal Station - 129 Hayward Ave
Where does the bus arrive in Milwaukee?

Image credit: Jeramey Jannene
Link to image attribution
Image credit: Payton Chung
Link to image attributionMain arrival station: Intermodal Station - 433 W ST Paul Ave
The Milwaukee Intermodal Station is the major transportation hub for rail and bus travel in Wisconsin. The station is Amtrak’s second busiest in the Midwest. It acts as a gateway for long-distance travel into the American West and also connects Milwaukee to the surrounding Midwest states via the Hiawatha service. Renovated in 2007, the Intermodal Station now also offers a range of intercity bus services from carriers, including Greyhound and Jefferson Lines. Local bus routes and The Hop streetcar service provide convenient local travel around Milwaukee. Located in the city’s downtown, The Intermodal Station has vast retail spaces, several museums, and pleasant waterways all on its doorstep.
All bus stations in Milwaukee:
Intermodal Station - 433 W ST Paul Ave
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