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Cheap bus tickets from St Louis to San Diego

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St Louis to San Diego Bus Schedule

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Bus from St Louis to San Diego: Journey Information

There are 2 intercity buses per day from St Louis to San Diego. Traveling by bus from St Louis to San Diego usually takes around 53 hours and 30 minutes, but the fastest FlixBus US bus can make the trip in 50 hours and 45 minutes.

Distance1561 mi (2512 km)
Shortest duration50h 45m
Cheapest price$166.94
Most frequent serviceFlixBus US
Bus lines1

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What bus companies travel from St Louis to San Diego?

There is one intercity bus company available to search and book on Wanderu that operates from St Louis to San Diego. FlixBus US is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US22d 5h 30m$305.67
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from St Louis to San Diego, and the average ticket for this route costs only .

Frequently asked questions about traveling by bus from St Louis to San Diego

The bus takes an average of 53 hours and 30 minutes to cover the 1561 miles from St Louis to San Diego. However, the fastest bus only takes 50 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Because many passengers travel from St Louis to San Diego at the beginning of the work week, Monday is usually the busiest day for buses. If you are planning to travel on a Monday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.

The first bus leaves at 4:00pm and the last bus leaves at 4:00pm. To see the times for all buses from St Louis to San Diego, enter your specific travel dates in the search bar.

There are usually only 2 buses per day from St Louis to San Diego. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.

Need more travel options? Consider taking the train from St Louis to San Diego; ticket prices start at $194.00.

City Information

St Louis

St. Louis, MO - STL-0

Image credit: Unsplash

St. Louis, MO - STL-1

Image credit: Unsplash

St. Louis, MO - STL-2

Image credit: Unsplash

St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.

Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.

Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.

The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.

San Diego

San Diego is known as "America's Finest City" for its sunny weather, white-sand beaches, and dazzling attractions from Belmont Park to SeaWorld. San Diego's 70 miles of pristine beaches include such gems as Mission Beach, Pacific Beach, La Jolla Cove, and Coronado Beach. The city's strong surfing culture may even inspire you to rent a surfboard and catch the epic waves, bro.

Visitors can spend days getting lost in Balboa Park, a 1,200-acre cultural hub which features 16 museums, immaculate gardens, and the world-famous San Diego Zoo. The historic heart of the city, Old Town, showcases San Diego's heritage and ties to Mexican culture, while other sights like the USS Midway pay tribute to the city's military and maritime history. Leave time for some evening exploring, too! San Diego is rated the #1 best city for craft beer in America, so don't miss out on the bars in the Gaslamp Quarter: 16 walkable blocks packed with nightlife and young crowds.

Two airports, as well as many bus and train options, mean it is easy to get to San Diego from afar or from nearby cities like Tijuana, Los Angeles, Phoenix, and Las Vegas.

Station Information

Where does the bus leave from in St Louis?

Main departure station: Gateway Station - 430 S 15th St

Most buses depart from the main station in St Louis.

All bus stations in St Louis:

  • Gateway Station - 430 S 15th St

Where does the bus arrive in San Diego?

Main arrival station: San Diego Greyhound Bus Stop

Buses arrive in San Diego at 4 stations, depending on which bus line you are traveling with.

All bus stations in San Diego:

  • San Diego Greyhound Bus Stop

  • 789 W Harbor Dr - Seaport Village

  • 2728 Congress St (Old Town SD)

  • La Jolla - UC San Diego

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Need a return trip from San Diego to St Louis?

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