Cheap bus tickets from Portsmouth to Winston-Salem
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Portsmouth to Winston-Salem Bus Schedule
Bus from Portsmouth to Winston-Salem: Journey Information
There is one daily bus from Portsmouth to Winston-Salem. Traveling by bus from Portsmouth to Winston-Salem usually takes around 29 hours and 50 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 697 mi (1122 km) |
| Shortest duration | 29h 50m |
| Cheapest price | $104.46 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Portsmouth to Winston-Salem?
There is one intercity bus company available to search and book on Wanderu that operates from Portsmouth to Winston-Salem. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 1d 5h 50m | $117.22 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Portsmouth to Winston-Salem, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Portsmouth to Winston-Salem
The bus takes an average of 29 hours and 50 minutes to cover the 697 miles from Portsmouth to Winston-Salem. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Sunday tends to be the busiest day for buses, as many passengers take the bus to Winston-Salem at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
There is usually only one bus per day from Portsmouth to Winston-Salem. It leaves the station in Portsmouth at 12:00am each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
There is usually only one bus per day from Portsmouth to Winston-Salem. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.
Need more travel options? Consider taking the train from Portsmouth, NH to Winston-Salem, NC; ticket prices start at $242.00.
City Information
Portsmouth

Image credit: Unsplash

Image credit: Unsplash

Image credit: Pixabay
Once a bustling seaport and now a popular summer holiday destination, Portsmouth, New Hampshire is well worth visiting. Just an hour and a half north of Boston, Portsmouth offers an exciting mix of unique history and contemporary experience.
Discover Portsmouth's history at the Strawbery Banke Museum and enjoy 10 acres worth of outdoor exhibits, consisting of tours of historic houses and buildings on their original foundations. Costumed actors will regale you with stories about each location.
For those interested in naval history, Portsmouth offers tours of the USS Albacore, a retired U.S. Navy submarine, as well as a gift shop for all your souvenir needs. Portsmouth is also home to hundreds of restaurants and cafes where you can taste local delicacies or world cuisine to refuel after a day of exploring.
Portsmouth is easily accessible by air, rail, road, and bus. Portsmouth International Airport offers several direct flights from various airports, while Boston's Logan Airport is only an hour south of the town. Amtrak's Downeaster travels to Portsmouth, with a gorgeous route during leaf-peeping season. C&J Bus Lines provide regular stops from Logan Airport and other cities.
Winston-Salem

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Ranked as one of the top places to live in the United States, Winston-Salem resulted from the merging of two separate towns in 1913.
The city's oldest and most visually arresting areas are found in what was once simply Salem, a town with a history going back to 1753. You can admire many of the original Moravian-style buildings at Old Salem Museums & Gardens and in the historic districts of West End and Ardmore.
Downtown also has some notable structures, including 100 North Main Street – the tallest office building in the region.
Meanwhile, the main strip when it comes to nightlife is Fourth Street, where bars and restaurants see a steady stream of patrons until long after dark. The presence of no less than six higher education institutions in the city ensures the scene remains fresh and vibrant.
Winston-Salem can be reached from over 175 other U.S. cities. Daily buses depart and arrive from the city's three bus terminals throughout the day, with destinations that include Raleigh, Richmond, and New York City. In addition, Amtrak operates passenger train services via the station at High Point. Its three lines span the region from New York to New Orleans.
Station Information
Where does the bus leave from in Portsmouth?
Main departure station: Portsmouth Bus Stop
The Greyhound bus stop on Hanover street is surrounded by a ton of restaurants and cafes, and, right across the street, is the Juicery and Soupery for all of your juice and soup needs. The stop itself has outdoor, covered seating, and there's a parking garage close by if you bring your car. There's a Hilton Garden Inn, Hampton Inn Suites, and The Inn Downtown just a block or two away if you want easy accommodations near the bus stop.
All bus stations in Portsmouth:
Portsmouth Bus Stop
Where does the bus arrive in Winston-Salem?

Image credit: Warren LeMay
Link to image attributionMain arrival station: Transp Ctr - 100 W 5th St
The Winston-Salem Transportation Center is on the corner of 5th Street & Trade Street, smack in the middle of the city. It's also commonly called the Greyhound bus station, since the carrier provides a lot of service across North Carolina and its neighboring states. There are plenty of great restaurants in the area, like Butcher & Bull Steakhouse, Downtown Thai & Pho, and Downtown Deli and Cafe, if you want to fill up before your trip. Or, if you want to stretch your legs, Bailey's Park is only a few blocks away and frequently has live music and events.
All bus stations in Winston-Salem:
Transp Ctr - 100 W 5th St
Get around town with Moovit
Need a return trip from Winston-Salem to Portsmouth?
Search Bus Tickets
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
- Bus Tickets
- United States
- North Carolina
- Winston-Salem
- Portsmouth, NH to Winston-Salem, NC






