Cheap bus tickets from Sioux Falls to La Crosse
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Sioux Falls to La Crosse Bus Schedule
Bus from Sioux Falls to La Crosse: Journey Information
There is one daily bus from Sioux Falls to La Crosse. Traveling by bus from Sioux Falls to La Crosse usually takes around 19 hours and 25 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 275 mi (443 km) |
| Shortest duration | 19h 25m |
| Cheapest price | $274.00 |
| Most frequent service | Jefferson Lines |
| Bus lines | 1 |
What bus companies travel from Sioux Falls to La Crosse?
There is one intercity bus company available to search and book on Wanderu that operates from Sioux Falls to La Crosse. Jefferson Lines is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Jefferson Lines | 1 | 19h 25m | $274.00 |
Book Jefferson Lines from Sioux Falls to La Crosse from $274. Typically there is one Jefferson Lines schedule per day from Sioux Falls to La Crosse and you can expect on average to pay for a Jefferson Lines ticket to La Crosse. In Sioux Falls, Jefferson Lines departs to La Crosse from 4110 W Maple St . In La Crosse, Jefferson Lines arrives at 314 Jay St .
An average trip on Jefferson Lines from Sioux Falls to La Crosse takes 19 hours and 25 minutes .
Frequently asked questions about traveling by bus from Sioux Falls to La Crosse
The bus takes an average of 19 hours and 25 minutes to cover the 275 miles from Sioux Falls to La Crosse. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from Sioux Falls to La Crosse. It leaves the station in Sioux Falls at 7:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
La Crosse
A busy college town blessed with lush and beautiful green zones, La Crosse is one of the best places to just chill out and unwind. The city's star attraction is the Grandad Bluff, which offers a panoramic view of the entire city and the Mississippi River. Hiking up the hill will certainly be a challenge, but the view from the top makes it all worthwhile. While staying in the city, don't miss out on the chance to go on a cruise aboard the La Crosse Queen, a replica paddle steamer, and unwind while enjoying the sunset. For some family fun, head over to the Children's Museum of La Crosse.
La Crosse does have a pretty reputable food scene, with a strong focus on beers and cheese curds. For an upscale dining experience with the best local dishes, The Waterfront Restaurant & Tavern is a local favorite that has a stellar reputation. Or head to the Dublin Square Irish Pub & Eatery for a combination of good foods and drinks.
La Crosse is easily accessible by bus or train, and regional flights operate out of the La Crosse Municipal Airport.
Station Information
Where does the bus leave from in Sioux Falls?
Main departure station: 4110 W Maple St
Most buses depart from the main station in Sioux Falls.
All bus stations in Sioux Falls:
4110 W Maple St
Where does the bus arrive in La Crosse?
Main arrival station: 314 Jay St
Buses to La Crosse stop at Jay Street in front of the Grand River Station. The aptly-named grand building features arching ceilings, marble decoration, and amenities like seating and vending machines inside. The station is conveniently located in downtown La Crosse with easy access to surrounding hotels, restaurants, and a rental car agency across the street. Bus lines, including Greyhound and Jefferson Lines, connect La Crosse to Minneapolis, Milwaukee, Chicago, and beyond.
All bus stations in La Crosse:
314 Jay St
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