Cheap bus tickets from Mount Pleasant to Gainesville
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Mount Pleasant to Gainesville Bus Schedule
Bus from Mount Pleasant to Gainesville: Journey Information
There are 3 intercity buses per day from Mount Pleasant to Gainesville. Traveling by bus from Mount Pleasant to Gainesville usually takes around 29 hours and 43 minutes, but the fastest Greyhound bus can make the trip in 24 hours and 55 minutes.
| Distance | 783 mi (1261 km) |
| Shortest duration | 24h 55m |
| Cheapest price | $215.47 |
| Most frequent service | Greyhound |
| Bus lines | 1 |

What bus companies travel from Mount Pleasant to Gainesville?
There is one intercity bus company available to search and book on Wanderu that operates from Mount Pleasant to Gainesville. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 3 | 1d 5h 44m | $235.70 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Mount Pleasant to Gainesville every day, with the average journey taking around 29 hours and 44 minutes to complete. Bus tickets for Greyhound trips to Gainesville usually start from $215.
Frequently asked questions about traveling by bus from Mount Pleasant to Gainesville
The bus takes an average of 29 hours and 43 minutes to cover the 783 miles from Mount Pleasant to Gainesville. However, the fastest bus only takes 24 hours and 55 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Friday is the busiest travel day for buses as people head from Mount Pleasant to Gainesville for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
The first bus leaves at 9:00am and the last bus leaves at 6:00pm. To see the times for all buses from Mount Pleasant to Gainesville, enter your specific travel dates in the search bar.
City Information
Gainesville



Blessed with amazing natural landmarks and a vibrant cultural life, Gainesville offers a whole new Florida experience that is far from the decadence often associated with the state. If you wish to explore creative works made by local artists, head over to the Cade Museum for Creativity & Invention, which features great exhibitions that dive into the life of many inventors and entrepreneurs. Another great museum to visit is the Samuel P. Harn Museum of Art. For those who want to marvel at the city’s natural landmarks, go for a hiking trip along the trails of Alfred A. Ring Park, or the Barr Hammock Preserve.
Gainesville’s local favorite is the 4 Rivers Smokehouse, which offers delicious briskets. For some of the freshest local dishes, head over to Alpin Bistro.
The main bus station in Gainesville is the Greyhound Bus Terminal located on NE 23rd Ave, which welcomes buses from Miami, Fort Lauderdale, Houston and beyond. There is no rail service to Gainesville. However, the city is part of Amtrak’s network via the carrier’s Thruway bus service, which operates out of the same station. The main airport is the Gainesville Regional Airport, which lies in the northeast part of the city.
Station Information
Where does the bus leave from in Mount Pleasant?
Main departure station: Total Stop Subway-sunoco
Most buses depart from the main station in Mount Pleasant.
All bus stations in Mount Pleasant:
Total Stop Subway-sunoco
Where does the bus arrive in Gainesville?
Main arrival station: Rosa Parks Downtown Station
These are the two stations where buses may stop when they arrive in Gainesville.
All bus stations in Gainesville:
Rosa Parks Downtown Station
Bus Terminal - 101 NE 23rd Ave
Get around town with Moovit
Need a return trip from Gainesville to Mount Pleasant?
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- United States
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- Gainesville
- Mount Pleasant, TX to Gainesville, FL






