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La Crosse to San Francisco bus

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La Crosse - San Francisco Bus Schedule

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Journey Information

There are 2 intercity buses per day from La Crosse to San Francisco. Traveling by bus from La Crosse to San Francisco usually takes around 66 hours and 32 minutes, but the fastest FlixBus US bus can make the trip in 66 hours and 30 minutes.

Distance1673 mi (2692 km)
Shortest duration66h 30m
Cheapest price$271.68
Most frequent serviceFlixBus US
Bus lines1

What bus companies travel from La Crosse to San Francisco?

There is one intercity bus company available to search and book on Wanderu that operates from La Crosse to San Francisco. FlixBus US is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US22d 18h 33m$271.68
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from La Crosse to San Francisco, and the average ticket for this route costs only .

Frequently Asked Questions

The bus takes an average of 66 hours and 32 minutes to cover the 1673 miles from La Crosse to San Francisco. However, the fastest bus only takes 66 hours and 30 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Travel trends tend to vary greatly for bus trips from La Crosse to San Francisco.

The first bus leaves at 2:00pm and the last bus leaves at 2:00pm. To see the times for all buses from La Crosse to San Francisco, enter your specific travel dates in the search bar.

There are usually only 2 buses per day from La Crosse to San Francisco. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.

Need more travel options? Consider taking the train from La Crosse to San Francisco; ticket prices start at $298.00.

City Information

La Crosse

La Crosse, WI - LSE-0

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La Crosse, WI - LSE-1

Image credit: Carl Wycoff

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La Crosse, WI - LSE-2

Image credit: Unsplash

A busy college town blessed with lush and beautiful green zones, La Crosse is one of the best places to just chill out and unwind. The city's star attraction is the Grandad Bluff, which offers a panoramic view of the entire city and the Mississippi River. Hiking up the hill will certainly be a challenge, but the view from the top makes it all worthwhile. While staying in the city, don't miss out on the chance to go on a cruise aboard the La Crosse Queen, a replica paddle steamer, and unwind while enjoying the sunset. For some family fun, head over to the Children's Museum of La Crosse.

La Crosse does have a pretty reputable food scene, with a strong focus on beers and cheese curds. For an upscale dining experience with the best local dishes, The Waterfront Restaurant & Tavern is a local favorite that has a stellar reputation. Or head to the Dublin Square Irish Pub & Eatery for a combination of good foods and drinks.

La Crosse is easily accessible by bus or train, and regional flights operate out of the La Crosse Municipal Airport.

San Francisco

San Francisco, CA - SFO-0

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San Francisco, CA - SFO-1

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San Francisco, CA - SFO-2

Image credit: Unsplash

Located in the heart of Northern California's Bay Area, San Francisco is a geographically small but culturally huge city known for its historic cable cars, active waterfront, and the eclectic mix of hippies and techies who call it home. While it might be one of the most expensive U.S. cities to live in, San Fran can actually be very cheap to visit, and there is no shortage of unique sights to see.

If the city's omnipresent fog (nicknamed "Karl the Fog" by locals) takes a break, the best views and Instagram photo ops of the world-famous Golden Gate Bridge are found in Golden Gate Park. Stroll through the oldest Chinatown in North America to find the perfect dim sum, or if you and your boo prefer a little Full House moment, try a romantic picnic at Alamo Square Park in front of the Victorian "Painted Ladies." After all, San Francisco is one of the best vacation destinations for couples.

Since the city is condensed onto a small peninsula, exploring by bike is an efficient and scenic way to get around. When you’re ready to travel beyond city limits, San Francisco is a convenient hub for trips throughout Northern California. It's actually the first stop on Wanderu's West Coast Wine Tour, with the next stop, obviously, in Napa Valley. Whether traveling by bus, train, or through either of the two nearby airports, San Francisco is a can't-miss destination.

Station Information

Where does the bus leave from in La Crosse?

Main departure station: 314 Jay St

Buses to La Crosse stop at Jay Street in front of the Grand River Station. The aptly-named grand building features arching ceilings, marble decoration, and amenities like seating and vending machines inside. The station is conveniently located in downtown La Crosse with easy access to surrounding hotels, restaurants, and a rental car agency across the street. Bus lines, including Greyhound and Jefferson Lines, connect La Crosse to Minneapolis, Milwaukee, Chicago, and beyond.

All bus stations in La Crosse:

  • 314 Jay St

  • University of Wisconsin

Where does the bus arrive in San Francisco?

Main arrival station: Salesforce Transit Center

All buses from La Crosse arrive at one main station in San Francisco.

All bus stations in San Francisco:

  • Salesforce Transit Center

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