Cheap bus tickets from Mexico City to Panama City
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Bus from Mexico City to Panama City: Journey Information
There are 2 intercity buses per day from Mexico City to Panama City. Traveling by bus from Mexico City to Panama City usually takes around 64 hours and 6 minutes, but the fastest FlixBus US bus can make the trip in 43 hours and 35 minutes.
| Distance | 1122 mi (1806 km) |
| Shortest duration | 43h 35m |
| Cheapest price | $286.35 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |
What bus companies travel from Mexico City to Panama City?
There is one intercity bus company available to search and book on Wanderu that operates from Mexico City to Panama City. FlixBus US is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 2 | 2d 16h 6m | $298.59 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Mexico City to Panama City, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Mexico City to Panama City
The bus takes an average of 64 hours and 6 minutes to cover the 1122 miles from Mexico City to Panama City. However, the fastest bus only takes 43 hours and 35 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 5:00pm and the last bus leaves at 11:00pm. To see the times for all buses from Mexico City to Panama City, enter your specific travel dates in the search bar.
City Information
Mexico City
Mexico City is one of the most vibrant and liveliest cities in the world, making it an exciting destination for all travelers. One of the must-see attractions in the city is the famous Museo Nacional de Antropología, which features an extensive collection from the city’s pre-Columbian era. Its star attraction is the famous Aztec Calendar Stone, also known as Piedra del Sol. For those who enjoy exploring the city’s amazing cultural life, the Palacio de Bellas Artes is a must-see destination. The art deco-style palace hosts some of the grandest cultural events around, including concerts, operas, etc. Another unique destination to check out is Teotihuacán, a world heritage site that contains some of the largest pre-Columbian pyramids in Mexico.
Mexico City’s food scene is so vast that it can be quite hard to fully explore in just a few days. Some notable foodie destinations include Pujol, Contramar, and Quintonil. If you want to grab one of those famous Mexican churros, head over to Churreria El Moro.
Mexico City’s four major bus stations are North, South, Observatorio, and TAPO. Some intercity buses leave directly from the Mexico City International Airport, which is located just about 7 miles east of the city center.
Station Information
Where does the bus leave from in Mexico City?
Image credit: Juan Carlos Fonseca Mata
Link to image attributionMain departure station: Eje Ctrl Lazaro Cardenas
Most buses depart from the main station in Mexico City.
All bus stations in Mexico City:
Eje Ctrl Lazaro Cardenas
Where does the bus arrive in Panama City?
Main arrival station: Panama City Bch Station
All buses from Mexico City arrive at one main station in Panama City.
All bus stations in Panama City:
Panama City Bch Station
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Need a return trip from Panama City to Mexico City?
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