Cheap bus tickets from San Francisco to Wilkes-Barre
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San Francisco to Wilkes-Barre Bus Schedule
Bus from San Francisco to Wilkes-Barre: Journey Information
There is one daily bus from San Francisco to Wilkes-Barre. Traveling by bus from San Francisco to Wilkes-Barre usually takes around 88 hours and 20 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 2463 mi (3963 km) |
| Shortest duration | 88h 20m |
| Cheapest price | $298.00 |
| Most frequent service | Greyhound |
| Bus lines | 1 |

What bus companies travel from San Francisco to Wilkes-Barre?
There is one intercity bus company available to search and book on Wanderu that operates from San Francisco to Wilkes-Barre. Greyhound is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 1 | 3d 16h 20m | $298.00 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from San Francisco to Wilkes-Barre every day, with the average journey taking around 88 hours and 20 minutes to complete. Bus tickets for Greyhound trips to Wilkes-Barre usually start from $298.
Frequently asked questions about traveling by bus from San Francisco to Wilkes-Barre
The bus takes an average of 88 hours and 20 minutes to cover the 2463 miles from San Francisco to Wilkes-Barre. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from San Francisco to Wilkes-Barre. It leaves the station in San Francisco at 9:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
There is usually only one bus per day from San Francisco to Wilkes-Barre. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.
Need more travel options? Consider taking the train from San Francisco to Wilkes-Barre; ticket prices start at $707.00.
City Information
San Francisco

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Located in the heart of Northern California's Bay Area, San Francisco is a geographically small but culturally huge city known for its historic cable cars, active waterfront, and the eclectic mix of hippies and techies who call it home. While it might be one of the most expensive U.S. cities to live in, San Fran can actually be very cheap to visit, and there is no shortage of unique sights to see.
If the city's omnipresent fog (nicknamed "Karl the Fog" by locals) takes a break, the best views and Instagram photo ops of the world-famous Golden Gate Bridge are found in Golden Gate Park. Stroll through the oldest Chinatown in North America to find the perfect dim sum, or if you and your boo prefer a little Full House moment, try a romantic picnic at Alamo Square Park in front of the Victorian "Painted Ladies." After all, San Francisco is one of the best vacation destinations for couples.
Since the city is condensed onto a small peninsula, exploring by bike is an efficient and scenic way to get around. When you’re ready to travel beyond city limits, San Francisco is a convenient hub for trips throughout Northern California. It's actually the first stop on Wanderu's West Coast Wine Tour, with the next stop, obviously, in Napa Valley. Whether traveling by bus, train, or through either of the two nearby airports, San Francisco is a can't-miss destination.
Wilkes-Barre

Image credit: Unsplash
Wilkes-Barre is a Pennsylvania city surrounded by the Pocono Mountains. Like much of the Poconos, Wilkes-Barre has its fair share of resorts, outdoor adventure, and entertainment options. Slip down rocky slides and soak in glacial meltwater "tubs" at Kirby Park and Seven Tubs Nature Area, or enjoy the urban greenery at the River Common. Coal mining put Wilkes-Barre on the map, and you can imagine what life was like in the 19th-century boom by visiting Eckley Miners' Village in Luzerne County.
Nightlife in Wilkes-Barre is exciting, and it all starts at the Mohegan Sun Pocono, a casino resort and racetrack. Test your luck on the slots, cards, or horse races, or simply enjoy the luxurious dining options and spa on-site. Downtown Wilkes-Barre also has solid restaurants and bars to choose from.
Although Amtrak trains do not stop in Wilkes-Barre, Amtrak Thruway buses connect the city to Philadelphia, where you can transfer to several of Philly's rail lines. Plus, Fullington Trailways and Martz operate intercity bus service to Wilkes-Barre from Scranton, Delaware Water Gap, New York, and more. The Wilkes-Barre/Scranton International Airport is convenient to reach from town and offers flights on several major airlines.
Station Information
Where does the bus leave from in San Francisco?

Image credit: 146109843@N05
Link to image attributionMain departure station: Salesforce Plaza
Behind a modern curved façade lies San Francisco’s commuter hub, the Salesforce Transit Center. This gateway to downtown San Francisco and the entire Bay Area welcomes tens of thousands of passengers every day. Finding your way around is easy thanks to more than 270 digital displays with transit information. The Salesforce Transit Center serves as a bus station for Greyhound and Amtrak Thruway buses, as well as several public transit options for convenient connections. A standout feature of the Salesforce Transit Center is a public five-acre rooftop park which gives travelers an open space to relax. Rotating food trucks, cafés, carts, and pop-up retail make this a dynamic and vibrant destination in itself.
All bus stations in San Francisco:
Salesforce Plaza
Where does the bus arrive in Wilkes-Barre?
Main arrival station: Intermodal Transp Ctr
All buses from San Francisco arrive at one main station in Wilkes-Barre.
All bus stations in Wilkes-Barre:
Intermodal Transp Ctr
Get around town with Moovit
Need a return trip from Wilkes-Barre to San Francisco?
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