Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
Journey Information
There are 2 intercity buses per day from Santa Ana to Greenville. Traveling by bus from Santa Ana to Greenville usually takes around 61 hours and 23 minutes, but the fastest Greyhound bus can make the trip in 58 hours and 45 minutes.
| Distance | 2016 mi (3244 km) |
| Shortest duration | 58h 45m |
| Cheapest price | $246.60 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
What bus companies travel from Santa Ana to Greenville?
There is one intercity bus company available to search and book on Wanderu that operates from Santa Ana to Greenville. Greyhound is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 2 | 2d 13h 23m | $294.40 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Santa Ana to Greenville every day, with the average journey taking around 61 hours and 23 minutes to complete. Bus tickets for Greyhound trips to Greenville usually start from $247.
Frequently Asked Questions
The bus takes an average of 61 hours and 23 minutes to cover the 2016 miles from Santa Ana to Greenville. However, the fastest bus only takes 58 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 4:00pm and the last bus leaves at 9:00pm. To see the times for all buses from Santa Ana to Greenville, enter your specific travel dates in the search bar.
There are usually only 2 buses per day from Santa Ana to Greenville. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.
Need more travel options? Consider taking the train from Santa Ana, CA to Greenville, SC; ticket prices start at $476.00.
City Information
Santa Ana
Image credit: Unsplash
Santa Ana is a sunny city in Orange County located between Anaheim and Irvine in the greater Los Angeles area. Downtown Santa Ana bustles with independent breweries, diverse restaurants, unique retail shops, weekly pop-up markets, and art centers. This lively downtown area, in addition to Santa Ana's live-work housing and creative working spaces, make it attractive to young professionals.
One of the most popular spots for visitors is the Santa Ana Zoo, where little ones can enjoy a carousel and mini-train ride along with the animal exhibits. Architecture enthusiasts will love seeing the Bowers Museum, built in a Mission Revival style, and the Heritage Museum, which has restored homes from the 1890s.
The Orange County Transportation Authority and several shuttle services provide transit within Santa Ana. Santa Ana is easily accessible from over 20 other cities by Amtrak Thruway bus or on the Amtrak Pacific Surfliner train. The primary airport for Orange County, John Wayne Airport, is located in Santa Ana and also makes it easy to travel to this vibrant SoCal spot.
Greenville
Image credit: Unsplash
Image credit: Unsplash
Image credit: Unsplash
As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
Station Information
Where does the bus leave from in Santa Ana?
Main departure station: Reg Transp Ctr - 1000 E Santa Ana Blvd
Most buses depart from the main station in Santa Ana.
All bus stations in Santa Ana:
Reg Transp Ctr - 1000 E Santa Ana Blvd
Where does the bus arrive in Greenville?
Main arrival station: Bus Terminal - 9 Hendrix Dr
All buses from Santa Ana arrive at one main station in Greenville.
All bus stations in Greenville:
Bus Terminal - 9 Hendrix Dr
Get around town with Moovit
Need a return trip from Greenville to Santa Ana?
Search Bus Tickets
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
Book buses and trains on the go with the Wanderu app.
Download our app and snag the best travel deals across North America & Europe.Learn more