Cheap bus tickets from Orlando to Santa Ana
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Orlando to Santa Ana Bus Schedule
Bus from Orlando to Santa Ana: Journey Information
There are 3 intercity buses per day from Orlando to Santa Ana. Traveling by bus from Orlando to Santa Ana usually takes around 64 hours and 23 minutes, but the fastest FlixBus US bus can make the trip in 60 hours and 30 minutes.
| Distance | 2176 mi (3502 km) |
| Shortest duration | 60h 30m |
| Cheapest price | $172.95 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Orlando to Santa Ana?
There is one intercity bus company available to search and book on Wanderu that operates from Orlando to Santa Ana. FlixBus US connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 3 | 2d 16h 24m | $363.10 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from Orlando to Santa Ana, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Orlando to Santa Ana
The bus takes an average of 64 hours and 23 minutes to cover the 2176 miles from Orlando to Santa Ana. However, the fastest bus only takes 60 hours and 30 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to Santa Ana, book your ticket for the last day of the week.
The first bus leaves at 7:00am and the last bus leaves at 9:00pm. To see the times for all buses from Orlando to Santa Ana, enter your specific travel dates in the search bar.
There are 3 scheduled buses that travel from Orlando to Santa Ana every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.
Need more travel options? Consider taking the train from Orlando, FL to Santa Ana, CA; ticket prices start at $554.00.
City Information
Orlando



Orlando is the Theme Park Capital of the World, thanks to the high density of thrilling parks like Walt Disney World, Universal Studios, SeaWorld, LEGOLAND, Gatorland and more. It's no wonder we rated Orlando the #1 travel destination for families. Family vacation or not, if the highlight of your trip is picking out a wand at Ollivanders in the Wizarding World of Harry Potter or finally meeting Elsa in the Magic Kingdom, you know we won't judge.
Winter Park and Thornton Park – not more theme parks, we promise – are trendy neighborhoods where you can experience some of Orlando's world-class shopping, dining, and craft beer. You can also immerse yourself in some of Florida's unique wildlife at Orlando Wetlands Park, or the more central Lake Eola Park downtown. Orlando enjoys an average of 233 days of sunshine a year, so even though it's one of the cheapest cities to visit over Spring Break, you'll soak up that sweet, sweet sun almost any time of year.
Craving the ocean? Head a few hours outside Orlando for some of Florida's gorgeous beaches like New Smyrna Beach, Cocoa Beach, and the Canaveral National Seashore. Two large airports, as well as many bus and train companies with service in the area, mean that traveling from Orlando to other sunny Florida destinations and beyond is a breeze.
Santa Ana

Image credit: Unsplash
Santa Ana is a sunny city in Orange County located between Anaheim and Irvine in the greater Los Angeles area. Downtown Santa Ana bustles with independent breweries, diverse restaurants, unique retail shops, weekly pop-up markets, and art centers. This lively downtown area, in addition to Santa Ana's live-work housing and creative working spaces, make it attractive to young professionals.
One of the most popular spots for visitors is the Santa Ana Zoo, where little ones can enjoy a carousel and mini-train ride along with the animal exhibits. Architecture enthusiasts will love seeing the Bowers Museum, built in a Mission Revival style, and the Heritage Museum, which has restored homes from the 1890s.
The Orange County Transportation Authority and several shuttle services provide transit within Santa Ana. Santa Ana is easily accessible from over 20 other cities by Amtrak Thruway bus or on the Amtrak Pacific Surfliner train. The primary airport for Orange County, John Wayne Airport, is located in Santa Ana and also makes it easy to travel to this vibrant SoCal spot.
Station Information
Where does the bus leave from in Orlando?

Image credit: Mark Goebel
Link to image attributionMain departure station: Bus Terminal - 555 N John Young Pkwy
The Bus Terminal at 555 N John Young Pkwy is the primary Greyhound bus station in Orlando, where travelers can catch a bus to other destinations throughout Florida and beyond. The station is located under 3 miles from downtown Orlando and the nearest SunRail station. There is also a Lynx public bus stop which conveniently drops people off right at the Greyhound Bus Terminal. Open 24 hours a day, the bus station provides vending machines if you need a quick bite, and there are also several fast food options within a short walk to fuel up before your trip.
All bus stations in Orlando:
Bus Terminal - 555 N John Young Pkwy
The Florida Mall
Where does the bus arrive in Santa Ana?
Main arrival station: Reg Transp Ctr - 1000 E Santa Ana Blvd
All buses from Orlando arrive at one main station in Santa Ana.
All bus stations in Santa Ana:
Reg Transp Ctr - 1000 E Santa Ana Blvd
Get around town with Moovit
Need a return trip from Santa Ana to Orlando?
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