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Cheap bus tickets from Panama City to Orlando

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Panama City to Orlando Bus Schedule

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Bus from Panama City to Orlando: Journey Information

There is one daily bus from Panama City to Orlando. Traveling by bus from Panama City to Orlando usually takes around 10 hours and 18 minutes, but the fastest Greyhound bus can make the trip in 10 hours and 9 minutes.

Distance281 mi (452 km)
Shortest duration10h 9m
Cheapest price$49.97
Most frequent serviceGreyhound
Bus lines1

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How much is a bus ticket from Panama City to Orlando?

Bus tickets for a trip from Panama City to Orlando cost $69.44 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.

Average bus ticket prices from Panama City to Orlando by travel date

$120$80$40AprMay

If you're planning to travel by bus from Panama City to Orlando in the next month, the average ticket price is expected to range from $61 to $113. The cheapest bus tickets available in the next few weeks are for trips departing on April 29, 2025.

If you’re looking to travel to Orlando this week, bus tickets are available starting at $61.

Monthly avg. prices

$100$80$60$40$20MJJASONDJFMA
If you're on the hunt for the cheapest bus tickets from Panama City to Orlando, mark your calendar for October. During this period, you can expect to find the lowest average ticket price of the year, just $71. However, taking the bus from Panama City to Orlando during November is not so cheap. This time of year, ticket prices often reach an average of $98. The best way to find deals on a trip in November is to plan ahead and book your bus ticket as early as possible.

Prices as travel date approaches

$150$120$90$60$303020100

To save money on bus tickets, buy them as early as possible. Bus carriers usually charge higher ticket prices the closer you book to the date of travel. Book your ticket at least 21 days in advance to save up to $64.73.

What bus companies travel from Panama City to Orlando?

There is one intercity bus company available to search and book on Wanderu that operates from Panama City to Orlando. Greyhound is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.

BusDaily TripsAvg. TimeAvg. Price
Greyhound110h 18m$79.23
  • Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from Panama City to Orlando every day, with the average journey taking around 10 hours and 18 minutes to complete. Bus tickets for Greyhound trips to Orlando usually start from $50.

Frequently asked questions about traveling by bus from Panama City to Orlando

The bus takes an average of 10 hours and 18 minutes to cover the 281 miles from Panama City to Orlando. However, the fastest bus only takes 10 hours and 9 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Sunday tends to be the busiest day for buses, as many passengers take the bus to Orlando at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Friday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Friday ticket is the way to go.

There is usually only one bus per day from Panama City to Orlando. It leaves the station in Panama City at 12:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.

There is usually only one bus per day from Panama City to Orlando. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.

City Information

Orlando

Orlando is the Theme Park Capital of the World, thanks to the high density of thrilling parks like Walt Disney World, Universal Studios, SeaWorld, LEGOLAND, Gatorland and more. It's no wonder we rated Orlando the #1 travel destination for families. Family vacation or not, if the highlight of your trip is picking out a wand at Ollivanders in the Wizarding World of Harry Potter or finally meeting Elsa in the Magic Kingdom, you know we won't judge.

Winter Park and Thornton Park – not more theme parks, we promise – are trendy neighborhoods where you can experience some of Orlando's world-class shopping, dining, and craft beer. You can also immerse yourself in some of Florida's unique wildlife at Orlando Wetlands Park, or the more central Lake Eola Park downtown. Orlando enjoys an average of 233 days of sunshine a year, so even though it's one of the cheapest cities to visit over Spring Break, you'll soak up that sweet, sweet sun almost any time of year.

Craving the ocean? Head a few hours outside Orlando for some of Florida's gorgeous beaches like New Smyrna Beach, Cocoa Beach, and the Canaveral National Seashore. Two large airports, as well as many bus and train companies with service in the area, mean that traveling from Orlando to other sunny Florida destinations and beyond is a breeze.

Station Information

Where does the bus leave from in Panama City?

Main departure station: Panama City Bch Station

Most buses depart from the main station in Panama City.

All bus stations in Panama City:

  • Panama City Bch Station

Where does the bus arrive in Orlando?

Orlando, FL - Bus Terminal (555 N John Young Pkwy) - ORLGLI-0

Image credit: Mark Goebel

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Main arrival station: Bus Terminal - 555 N John Young Pkwy

The Bus Terminal at 555 N John Young Pkwy is the primary Greyhound bus station in Orlando, where travelers can catch a bus to other destinations throughout Florida and beyond. The station is located under 3 miles from downtown Orlando and the nearest SunRail station. There is also a Lynx public bus stop which conveniently drops people off right at the Greyhound Bus Terminal. Open 24 hours a day, the bus station provides vending machines if you need a quick bite, and there are also several fast food options within a short walk to fuel up before your trip.

All bus stations in Orlando:

  • Bus Terminal - 555 N John Young Pkwy

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