Cheap bus tickets from Port Saint Lucie to Gainesville
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Port Saint Lucie to Gainesville Bus Schedule
Bus from Port Saint Lucie to Gainesville: Journey Information
There are 6 intercity buses per day from Port Saint Lucie to Gainesville. Traveling by bus from Port Saint Lucie to Gainesville usually takes around 4 hours and 39 minutes, but the fastest RedCoach Economy bus can make the trip in 4 hours,
| Distance | 203 mi (327 km) |
| Shortest duration | 4h 0m |
| Cheapest price | $38.99 |
| Trips per day | 4 |
| Most frequent service | FlixBus US |
| Bus lines | 5 |

How much is a bus ticket from Port Saint Lucie to Gainesville?
Bus tickets for a trip from Port Saint Lucie to Gainesville cost $59.66 on average. Tickets cheaper than $59.66 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Monthly avg. prices
What bus companies travel from Port Saint Lucie to Gainesville?
There are 5 bus lines from Port Saint Lucie to Gainesville available for you to search and compare on Wanderu. With 3 daily trips, FlixBus US usually has the most buses running on any given day. Here are some time and price comparisons for all the available options:
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 3 | 7h 37m | $92.72 |
| RedCoach Business | 1 | 4h 20m | $67.91 |
| RedCoach Economy | 2 | 4h 9m | $55.74 |
RedCoach First Class | 1 | 4h 25m | $85.02 |
| Tornado Bus | 1 | 9h 37m | $150.00 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from Port Saint Lucie to Gainesville, and the average ticket for this route costs only .
Book RedCoach Business from Port Saint Lucie to Gainesville from $45. Typically there is one RedCoach Business schedule per day from Port Saint Lucie to Gainesville and you can expect on average to pay for a RedCoach Business ticket to Gainesville. In Port Saint Lucie, RedCoach Business departs to Gainesville from Port Saint Lucie Service Plaza - Florida Turnpike Mile 144 . In Gainesville, RedCoach Business arrives at 1956 Gale Lemerand Drive .
An average trip on RedCoach Business from Port Saint Lucie to Gainesville takes 4 hours and 20 minutes , while the fastest available RedCoach Business trip will get you to Gainesville in 4 hours and 0 minutes .
On weekends, RedCoach Business offers 1 trip per day and you could expect to pay for a one way ticket for your weekend getaway trip to Gainesville.
Book RedCoach Economy from Port Saint Lucie to Gainesville from $39. There are 2 trips per day offered by RedCoach Economy from Port Saint Lucie to Gainesville and you can expect on average to pay for a RedCoach Economy ticket to Gainesville. In Port Saint Lucie, RedCoach Economy departs to Gainesville from Port Saint Lucie Service Plaza - Florida Turnpike Mile 144 . In Gainesville, RedCoach Economy arrives at 1956 Gale Lemerand Drive .
An average trip on RedCoach Economy from Port Saint Lucie to Gainesville takes 4 hours and 9 minutes , while the fastest available RedCoach Economy trip will get you to Gainesville in 4 hours and 0 minutes .
On weekends, RedCoach Economy offers 2 trips per day. A one way ticket costs for a weekend trip to Gainesville.
Book RedCoach First Class from Port Saint Lucie to Gainesville from $56. Typically there is one RedCoach First Class schedule per day from Port Saint Lucie to Gainesville and you can expect on average to pay for a RedCoach First Class ticket to Gainesville. In Port Saint Lucie, RedCoach First Class departs to Gainesville from Port Saint Lucie Service Plaza - Florida Turnpike Mile 144 . In Gainesville, RedCoach First Class arrives at 1956 Gale Lemerand Drive .
An average trip on RedCoach First Class from Port Saint Lucie to Gainesville takes 4 hours and 25 minutes , while the fastest available RedCoach First Class trip will get you to Gainesville in 4 hours and 0 minutes .
On weekends, RedCoach First Class offers 1 trip per day and you could expect to pay for a one way ticket for your weekend getaway trip to Gainesville.
Frequently asked questions about traveling by bus from Port Saint Lucie to Gainesville
The bus takes an average of 4 hours and 39 minutes to cover the 203 miles from Port Saint Lucie to Gainesville. However, the fastest bus only takes 4 hours. In other words, you'll have plenty of time to rest and relax on the road. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Travelers prefer riding the bus on Saturday to enjoy the weekend in Gainesville. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
The first bus leaves at 1:00am and the last bus leaves at 7:00pm. To see the times for all buses from Port Saint Lucie to Gainesville, enter your specific travel dates in the search bar.
City Information
Port Saint Lucie

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Map out a Florida vacation and it will most probably lead you to Port Saint Lucie. Situated on the Atlantic Ocean coastline of southern Florida, the city includes long ribbons of pristine sand beaches that are an ideal escape from it all.
Head inland, and you'll find a heart ringed by stunning waterways and roughly 20,000 acres of a nature reserve that are just waiting to be discovered. There are various opportunities to try your luck on a fishing adventure, strike out with a rucksack on a day's hike, or ride horses at full gallop in the shallows. Should you prefer, there's also ample opportunity to take to the saddle of a mountain bike to raise the heart rate or enjoy a sedate round of golf at PGA-level facilities.
Neatly positioned between Miami to the south and Orlando to the north, Port Saint Lucie makes for a great way to break up a journey. Buses make frequent arrivals at Port Saint Lucie Service Plaza at Florida Turnpike Mile 144, just two miles from the city center, as well as at 2031 SW Gatlin Blvd and La Bonita.
The ride to Orlando or Miami will take around 3.5 hours, while if you choose, it's possible to head as far afield as Philadelphia, too.
Gainesville



Blessed with amazing natural landmarks and a vibrant cultural life, Gainesville offers a whole new Florida experience that is far from the decadence often associated with the state. If you wish to explore creative works made by local artists, head over to the Cade Museum for Creativity & Invention, which features great exhibitions that dive into the life of many inventors and entrepreneurs. Another great museum to visit is the Samuel P. Harn Museum of Art. For those who want to marvel at the city’s natural landmarks, go for a hiking trip along the trails of Alfred A. Ring Park, or the Barr Hammock Preserve.
Gainesville’s local favorite is the 4 Rivers Smokehouse, which offers delicious briskets. For some of the freshest local dishes, head over to Alpin Bistro.
The main bus station in Gainesville is the Greyhound Bus Terminal located on NE 23rd Ave, which welcomes buses from Miami, Fort Lauderdale, Houston and beyond. There is no rail service to Gainesville. However, the city is part of Amtrak’s network via the carrier’s Thruway bus service, which operates out of the same station. The main airport is the Gainesville Regional Airport, which lies in the northeast part of the city.
Station Information
Where does the bus leave from in Port Saint Lucie?
Main departure station: Port Saint Lucie Service Plaza - Florida Turnpike Mile 144
Buses to Gainesville leave from 3 stations in Port Saint Lucie.
All bus stations in Port Saint Lucie:
Port Saint Lucie Service Plaza - Florida Turnpike Mile 144
Prt St Lucie (Park & Ride)
La Bonita
Where does the bus arrive in Gainesville?
Main arrival station: 1956 Gale Lemerand Drive
Buses arrive in Gainesville at 4 stations, depending on which bus line you are traveling with.
All bus stations in Gainesville:
1956 Gale Lemerand Drive
Rosa Parks Downtown Station
Gainesville Bus Stop
3509 SW Williston Rd
Get around town with Moovit
Need a return trip from Gainesville to Port Saint Lucie?
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- Bus Tickets
- United States
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- Port Saint Lucie, FL to Gainesville, FL






