Cheap bus tickets from Des Moines to Amarillo
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Bus from Des Moines to Amarillo: Journey Information
There are 3 intercity buses per day from Des Moines to Amarillo. Traveling by bus from Des Moines to Amarillo usually takes around 21 hours and 57 minutes, but the fastest FlixBus US bus can make the trip in 20 hours and 15 minutes.
Distance | 626 mi (1007 km) |
Shortest duration | 20h 15m |
Cheapest price | $176.95 |
Most frequent service | FlixBus US |
Bus lines | 1 |

What bus companies travel from Des Moines to Amarillo?
There is one intercity bus company available to search and book on Wanderu that operates from Des Moines to Amarillo. FlixBus US connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
Bus | Daily Trips | Avg. Time | Avg. Price |
---|---|---|---|
FlixBus US | 3 | 21h 57m | $204.68 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from Des Moines to Amarillo, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Des Moines to Amarillo
The bus takes an average of 21 hours and 57 minutes to cover the 626 miles from Des Moines to Amarillo. However, the fastest bus only takes 20 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
The first bus leaves at 2:00am and the last bus leaves at 11:00pm. To see the times for all buses from Des Moines to Amarillo, enter your specific travel dates in the search bar.
City Information
Des Moines

Image credit: Unsplash
Des Moines is the capital city of Iowa and the most populous city in the state. It has been named the third-largest insurance capital in the world because of its relevance in the US insurance industry. Des Moines is home to historic landmarks, especially in the East Village area. These include the gold-domed Iowa State Capitol building. Art lovers can visit the Des Moines Art Center, which has notable contemporary collections, and the Pappajohn Sculpture Park, a pedestrian space with public attractions. Des Moines also has spots for outdoor adventures, like the Blank Park Zoo, Greater Des Moines Botanical Garden, and Living History Farms.
Des Moines offers diverse places for entertainment, like the Praire Meadows Casino, Racetrack & Hotel, and the Salisbury House & Gardens, a concert venue in a 1920s manor. In the heart of the city is Downtown Des Moines, which has different attractions and entertainment venues, festivals and concerts, shopping spots, sports teams, restaurants, bars, and breweries.
It's very easy to access Des Moines when you're traveling by bus. Over a hundred neighboring cities offer bus lines to the city, powered by companies like Jefferson Lines, Tornado Bus, Burlington Trailways, and El Expreso Bus. The Des Moines Area Regional Transit Authority also provides bus routes throughout the city.
Station Information
Where does the bus leave from in Des Moines?
Main departure station: Bus Station - 1501 2nd St
Most buses depart from the main station in Des Moines.
All bus stations in Des Moines:
Bus Station - 1501 2nd St
Where does the bus arrive in Amarillo?
Main arrival station: 700 S Tyler St
All buses from Des Moines arrive at one main station in Amarillo.
All bus stations in Amarillo:
700 S Tyler St
Get around town with Moovit
Need a return trip from Amarillo to Des Moines?
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